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897 related items for PubMed ID: 11439344

  • 1. Low concentrations of paclitaxel induce cell type-dependent p53, p21 and G1/G2 arrest instead of mitotic arrest: molecular determinants of paclitaxel-induced cytotoxicity.
    Giannakakou P, Robey R, Fojo T, Blagosklonny MV.
    Oncogene; 2001 Jun 28; 20(29):3806-13. PubMed ID: 11439344
    [Abstract] [Full Text] [Related]

  • 2. Mechanism of G1-like arrest by low concentrations of paclitaxel: next cell cycle p53-dependent arrest with sub G1 DNA content mediated by prolonged mitosis.
    Demidenko ZN, Kalurupalle S, Hanko C, Lim CU, Broude E, Blagosklonny MV.
    Oncogene; 2008 Jul 24; 27(32):4402-10. PubMed ID: 18469851
    [Abstract] [Full Text] [Related]

  • 3. Mechanisms of Taxol-induced cell death are concentration dependent.
    Torres K, Horwitz SB.
    Cancer Res; 1998 Aug 15; 58(16):3620-6. PubMed ID: 9721870
    [Abstract] [Full Text] [Related]

  • 4. Low doses of paclitaxel potently induce apoptosis in human retinoblastoma Y79 cells by up-regulating E2F1.
    Drago-Ferrante R, Santulli A, Di Fiore R, Giuliano M, Calvaruso G, Tesoriere G, Vento R.
    Int J Oncol; 2008 Oct 15; 33(4):677-87. PubMed ID: 18813780
    [Abstract] [Full Text] [Related]

  • 5. Paclitaxel increases p21 synthesis and accumulation of its AKT-phosphorylated form in the cytoplasm of cancer cells.
    Héliez C, Baricault L, Barboule N, Valette A.
    Oncogene; 2003 May 22; 22(21):3260-8. PubMed ID: 12761496
    [Abstract] [Full Text] [Related]

  • 6. Bcl-2 and Bcl-xL are important for the induction of paclitaxel resistance in human hepatocellular carcinoma cells.
    Chun E, Lee KY.
    Biochem Biophys Res Commun; 2004 Mar 12; 315(3):771-9. PubMed ID: 14975768
    [Abstract] [Full Text] [Related]

  • 7. Inactivation of p53 in a human ovarian cancer cell line increases the sensitivity to paclitaxel by inducing G2/M arrest and apoptosis.
    Vikhanskaya F, Vignati S, Beccaglia P, Ottoboni C, Russo P, D'Incalci M, Broggini M.
    Exp Cell Res; 1998 May 25; 241(1):96-101. PubMed ID: 9633517
    [Abstract] [Full Text] [Related]

  • 8. Protein levels of p21, p27, cyclin E and Bax predict sensitivity to cisplatin and paclitaxel in head and neck squamous cell carcinomas.
    Taguchi T, Kato Y, Baba Y, Nishimura G, Tanigaki Y, Horiuchi C, Mochimatsu I, Tsukuda M.
    Oncol Rep; 2004 Feb 25; 11(2):421-6. PubMed ID: 14719078
    [Abstract] [Full Text] [Related]

  • 9. p53 status does not affect sensitivity of human ovarian cancer cell lines to paclitaxel.
    Debernardis D, Siré EG, De Feudis P, Vikhanskaya F, Valenti M, Russo P, Parodi S, D'Incalci M, Broggini M.
    Cancer Res; 1997 Mar 01; 57(5):870-4. PubMed ID: 9041188
    [Abstract] [Full Text] [Related]

  • 10. Sequential activation and inactivation of G2 checkpoints for selective killing of p53-deficient cells by microtubule-active drugs.
    Blagosklonny MV.
    Oncogene; 2002 Sep 12; 21(41):6249-54. PubMed ID: 12214265
    [Abstract] [Full Text] [Related]

  • 11. Role of p53 in G2/M cell cycle arrest and apoptosis in response to gamma-irradiation in ovarian carcinoma cell lines.
    Concin N, Stimpfl M, Zeillinger C, Wolff U, Hefler L, Sedlak J, Leodolter S, Zeillinger R.
    Int J Oncol; 2003 Jan 12; 22(1):51-7. PubMed ID: 12469184
    [Abstract] [Full Text] [Related]

  • 12. Investigation of the role of Bax, p21/Waf1 and p53 as determinants of cellular responses in HCT116 colorectal cancer cells exposed to the novel cytotoxic ruthenium(II) organometallic agent, RM175.
    Hayward RL, Schornagel QC, Tente R, Macpherson JS, Aird RE, Guichard S, Habtemariam A, Sadler P, Jodrell DI.
    Cancer Chemother Pharmacol; 2005 Jun 12; 55(6):577-83. PubMed ID: 15726367
    [Abstract] [Full Text] [Related]

  • 13. Dissociation between cell cycle arrest and apoptosis can occur in Li-Fraumeni cells heterozygous for p53 gene mutations.
    Delia D, Goi K, Mizutani S, Yamada T, Aiello A, Fontanella E, Lamorte G, Iwata S, Ishioka C, Krajewski S, Reed JC, Pierotti MA.
    Oncogene; 1997 May 08; 14(18):2137-47. PubMed ID: 9174049
    [Abstract] [Full Text] [Related]

  • 14. p21 promotes ceramide-induced apoptosis and antagonizes the antideath effect of Bcl-2 in human hepatocarcinoma cells.
    Kang KH, Kim WH, Choi KH.
    Exp Cell Res; 1999 Dec 15; 253(2):403-12. PubMed ID: 10585263
    [Abstract] [Full Text] [Related]

  • 15. Adenovirus-mediated expression of p53 or p21 in a papillary serous endometrial carcinoma cell line (SPEC-2) results in both growth inhibition and apoptotic cell death: potential application of gene therapy to endometrial cancer.
    Ramondetta L, Mills GB, Burke TW, Wolf JK.
    Clin Cancer Res; 2000 Jan 15; 6(1):278-84. PubMed ID: 10656459
    [Abstract] [Full Text] [Related]

  • 16. Involvement of p21 in mitotic exit after paclitaxel treatment in MCF-7 breast adenocarcinoma cell line.
    Barboule N, Chadebech P, Baldin V, Vidal S, Valette A.
    Oncogene; 1997 Dec 04; 15(23):2867-75. PubMed ID: 9419978
    [Abstract] [Full Text] [Related]

  • 17. A transcriptional activation function of p53 is dispensable for and inhibitory of its apoptotic function.
    Kokontis JM, Wagner AJ, O'Leary M, Liao S, Hay N.
    Oncogene; 2001 Feb 08; 20(6):659-68. PubMed ID: 11313999
    [Abstract] [Full Text] [Related]

  • 18. Implication of p53 in growth arrest and apoptosis induced by the synthetic retinoid CD437 in human lung cancer cells.
    Sun SY, Yue P, Wu GS, El-Deiry WS, Shroot B, Hong WK, Lotan R.
    Cancer Res; 1999 Jun 15; 59(12):2829-33. PubMed ID: 10383141
    [Abstract] [Full Text] [Related]

  • 19. Low-dose fractionated radiation potentiates the effects of Paclitaxel in wild-type and mutant p53 head and neck tumor cell lines.
    Dey S, Spring PM, Arnold S, Valentino J, Chendil D, Regine WF, Mohiuddin M, Ahmed MM.
    Clin Cancer Res; 2003 Apr 15; 9(4):1557-65. PubMed ID: 12684432
    [Abstract] [Full Text] [Related]

  • 20. The proliferative inhibition and apoptotic mechanism of Saikosaponin D in human non-small cell lung cancer A549 cells.
    Hsu YL, Kuo PL, Lin CC.
    Life Sci; 2004 Jul 23; 75(10):1231-42. PubMed ID: 15219811
    [Abstract] [Full Text] [Related]

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