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297 related items for PubMed ID: 11443130

  • 1. Insulin rescues retinal neurons from apoptosis by a phosphatidylinositol 3-kinase/Akt-mediated mechanism that reduces the activation of caspase-3.
    Barber AJ, Nakamura M, Wolpert EB, Reiter CE, Seigel GM, Antonetti DA, Gardner TW.
    J Biol Chem; 2001 Aug 31; 276(35):32814-21. PubMed ID: 11443130
    [Abstract] [Full Text] [Related]

  • 2. Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor-dependent sympathetic neurons.
    Crowder RJ, Freeman RS.
    J Neurosci; 1998 Apr 15; 18(8):2933-43. PubMed ID: 9526010
    [Abstract] [Full Text] [Related]

  • 3. PDGF- and insulin/IGF-1-specific distinct modes of class IA PI 3-kinase activation in normal rat retinas and RGC-5 retinal ganglion cells.
    Biswas SK, Zhao Y, Nagalingam A, Gardner TW, Sandirasegarane L.
    Invest Ophthalmol Vis Sci; 2008 Aug 15; 49(8):3687-98. PubMed ID: 18421086
    [Abstract] [Full Text] [Related]

  • 4. A phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFkappaB in human endothelial cells.
    Madge LA, Pober JS.
    J Biol Chem; 2000 May 19; 275(20):15458-65. PubMed ID: 10748004
    [Abstract] [Full Text] [Related]

  • 5. Phosphatidylinositol 3-kinase (PI-3K)/Akt but not PI-3K/p70 S6 kinase signaling mediates IGF-1-promoted lens epithelial cell survival.
    Chandrasekher G, Sailaja D.
    Invest Ophthalmol Vis Sci; 2004 Oct 19; 45(10):3577-88. PubMed ID: 15452065
    [Abstract] [Full Text] [Related]

  • 6. Phosphatidylinositol 3-kinase-mediated regulation of neuronal apoptosis and necrosis by insulin and IGF-I.
    Ryu BR, Ko HW, Jou I, Noh JS, Gwag BJ.
    J Neurobiol; 1999 Jun 15; 39(4):536-46. PubMed ID: 10380075
    [Abstract] [Full Text] [Related]

  • 7. Nerve growth factor-induced PKB/Akt activity is sustained by phosphoinositide 3-kinase dependent and independent signals in sympathetic neurons.
    Virdee K, Xue L, Hemmings BA, Goemans C, Heumann R, Tolkovsky AM.
    Brain Res; 1999 Aug 07; 837(1-2):127-42. PubMed ID: 10433995
    [Abstract] [Full Text] [Related]

  • 8. Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.
    Kulik G, Klippel A, Weber MJ.
    Mol Cell Biol; 1997 Mar 07; 17(3):1595-606. PubMed ID: 9032287
    [Abstract] [Full Text] [Related]

  • 9. Insulin-like growth factor-I is a potential trophic factor for amacrine cells.
    Politi LE, Rotstein NP, Salvador G, Giusto NM, Insua MF.
    J Neurochem; 2001 Feb 07; 76(4):1199-211. PubMed ID: 11181839
    [Abstract] [Full Text] [Related]

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  • 11. Lithium activates the serine/threonine kinase Akt-1 and suppresses glutamate-induced inhibition of Akt-1 activity in neurons.
    Chalecka-Franaszek E, Chuang DM.
    Proc Natl Acad Sci U S A; 1999 Jul 20; 96(15):8745-50. PubMed ID: 10411946
    [Abstract] [Full Text] [Related]

  • 12. Role of PI 3-kinase, Akt and Bcl-2-related proteins in sustaining the survival of neurotrophic factor-independent adult sympathetic neurons.
    Orike N, Middleton G, Borthwick E, Buchman V, Cowen T, Davies AM.
    J Cell Biol; 2001 Sep 03; 154(5):995-1005. PubMed ID: 11524433
    [Abstract] [Full Text] [Related]

  • 13. Roles of phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways in stimulation of vascular smooth muscle cell migration and deoxyriboncleic acid synthesis by insulin-like growth factor-I.
    Imai Y, Clemmons DR.
    Endocrinology; 1999 Sep 03; 140(9):4228-35. PubMed ID: 10465296
    [Abstract] [Full Text] [Related]

  • 14. Putative role of the phosphatidylinositol 3-kinase-Akt signaling pathway in the survival of granulosa cells.
    Westfall SD, Hendry IR, Obholz KL, Rueda BR, Davis JS.
    Endocrine; 2000 Jun 03; 12(3):315-21. PubMed ID: 10963053
    [Abstract] [Full Text] [Related]

  • 15. Insulin-like growth factor-I protects axotomized rat retinal ganglion cells from secondary death via PI3-K-dependent Akt phosphorylation and inhibition of caspase-3 In vivo.
    Kermer P, Klöcker N, Labes M, Bähr M.
    J Neurosci; 2000 Jan 15; 20(2):2-8. PubMed ID: 10632601
    [Abstract] [Full Text] [Related]

  • 16. Insulin-like growth factor I-mediated protection from rapamycin-induced apoptosis is independent of Ras-Erk1-Erk2 and phosphatidylinositol 3'-kinase-Akt signaling pathways.
    Thimmaiah KN, Easton J, Huang S, Veverka KA, Germain GS, Harwood FC, Houghton PJ.
    Cancer Res; 2003 Jan 15; 63(2):364-74. PubMed ID: 12543789
    [Abstract] [Full Text] [Related]

  • 17. Hydrogen peroxide generated during cellular insulin stimulation is integral to activation of the distal insulin signaling cascade in 3T3-L1 adipocytes.
    Mahadev K, Wu X, Zilbering A, Zhu L, Lawrence JT, Goldstein BJ.
    J Biol Chem; 2001 Dec 28; 276(52):48662-9. PubMed ID: 11598110
    [Abstract] [Full Text] [Related]

  • 18. Midkine inhibits caspase-dependent apoptosis via the activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase in cultured neurons.
    Owada K, Sanjo N, Kobayashi T, Mizusawa H, Muramatsu H, Muramatsu T, Michikawa M.
    J Neurochem; 1999 Nov 28; 73(5):2084-92. PubMed ID: 10537068
    [Abstract] [Full Text] [Related]

  • 19. Growth factor-stimulated phosphorylation of Akt and p70(S6K) is differentially inhibited by LY294002 and Wortmannin.
    Adi S, Wu NY, Rosenthal SM.
    Endocrinology; 2001 Jan 28; 142(1):498-501. PubMed ID: 11145615
    [Abstract] [Full Text] [Related]

  • 20. Growth differentiation factor-15 prevents low potassium-induced cell death of cerebellar granule neurons by differential regulation of Akt and ERK pathways.
    Subramaniam S, Strelau J, Unsicker K.
    J Biol Chem; 2003 Mar 14; 278(11):8904-12. PubMed ID: 12514175
    [Abstract] [Full Text] [Related]

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