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159 related items for PubMed ID: 11454687

  • 21. Cytotoxicity of bioreductive drug tirapazamine is increased by application of electric pulses in SA-1 tumours in mice.
    Cemazar M, Parkins CS, Holder AL, Kranjc S, Chaplin DJ, Sersa G.
    Anticancer Res; 2001; 21(2A):1151-6. PubMed ID: 11396155
    [Abstract] [Full Text] [Related]

  • 22. Photochemical and photobiological studies of tirapazamine (SR 4233) and related quinoxaline 1,4-Di-N-oxide analogues.
    Inbaraj JJ, Motten AG, Chignell CF.
    Chem Res Toxicol; 2003 Feb; 16(2):164-70. PubMed ID: 12588187
    [Abstract] [Full Text] [Related]

  • 23. The effect of functional groups on reduction and activation of quinone bioreductive agents by DT-diaphorase.
    Fourie J, Oleschuk CJ, Guziec F, Guziec L, Fiterman DJ, Monterrosa C, Begleiter A.
    Cancer Chemother Pharmacol; 2002 Feb; 49(2):101-10. PubMed ID: 11862423
    [Abstract] [Full Text] [Related]

  • 24. Cisplatin anti-tumour potentiation by tirapazamine results from a hypoxia-dependent cellular sensitization to cisplatin.
    Kovacs MS, Hocking DJ, Evans JW, Siim BG, Wouters BG, Brown JM.
    Br J Cancer; 1999 Jun; 80(8):1245-51. PubMed ID: 10376978
    [Abstract] [Full Text] [Related]

  • 25. DNA base damage by the antitumor agent 3-amino-1,2,4-benzotriazine 1,4-dioxide (tirapazamine).
    Birincioglu M, Jaruga P, Chowdhury G, Rodriguez H, Dizdaroglu M, Gates KS.
    J Am Chem Soc; 2003 Sep 24; 125(38):11607-15. PubMed ID: 13129365
    [Abstract] [Full Text] [Related]

  • 26. Subcellular Location of Tirapazamine Reduction Dramatically Affects Aerobic but Not Anoxic Cytotoxicity.
    Guise CP, Abbattista MR, Anderson RF, Li D, Taghipouran R, Tsai A, Lee SJ, Smaill JB, Denny WA, Hay MP, Wilson WR, Hicks KO, Patterson AV.
    Molecules; 2020 Oct 22; 25(21):. PubMed ID: 33105798
    [Abstract] [Full Text] [Related]

  • 27. DNA repair mechanisms are involved in the hypoxia-dependent toxicity of NLCQ-1 (NSC 709257) and its synergistic interaction with alkylating agents.
    Papadopoulou MV, Bloomer WD.
    In Vivo; 2007 Oct 22; 21(2):175-80. PubMed ID: 17436565
    [Abstract] [Full Text] [Related]

  • 28. Combination of the bioreductive drug tirapazamine with the chemotherapeutic prodrug cyclophosphamide for P450/P450-reductase-based cancer gene therapy.
    Jounaidi Y, Waxman DJ.
    Cancer Res; 2000 Jul 15; 60(14):3761-9. PubMed ID: 10919648
    [Abstract] [Full Text] [Related]

  • 29. [Inhibitory effect of tirapazamine combined with phosphatidylinositol 3-kinase inhibitor LY294002 to ovarian cancer cells].
    Ren Y, Zha X, Zhang GN.
    Zhonghua Yi Xue Za Zhi; 2007 May 08; 87(17):1204-6. PubMed ID: 17686243
    [Abstract] [Full Text] [Related]

  • 30. Modification of the antitumor activity of chemotherapeutic drugs by the hypoxic cytotoxic agent tirapazamine.
    Dorie MJ, Brown JM.
    Cancer Chemother Pharmacol; 1997 May 08; 39(4):361-6. PubMed ID: 9025778
    [Abstract] [Full Text] [Related]

  • 31. UVC inhibits HIF-1alpha protein translation by a DNA damage- and topoisomerase I-independent pathway.
    Rapisarda A, Melillo G.
    Oncogene; 2007 Oct 18; 26(48):6875-84. PubMed ID: 17496931
    [Abstract] [Full Text] [Related]

  • 32. An investigation of the molecular basis for the synergistic interaction of tirapazamine and cisplatin.
    Goldberg Z, Evans J, Birrell G, Brown JM.
    Int J Radiat Oncol Biol Phys; 2001 Jan 01; 49(1):175-82. PubMed ID: 11163512
    [Abstract] [Full Text] [Related]

  • 33. Oxygen dependence of the metabolic activation and cytotoxicity of tirapazamine: implications for extravascular transport and activity in tumors.
    Hicks KO, Siim BG, Pruijn FB, Wilson WR.
    Radiat Res; 2004 Jun 01; 161(6):656-66. PubMed ID: 15161354
    [Abstract] [Full Text] [Related]

  • 34. Antiproliferation of HeLa cells by 3,4,5-trihydroxy-N-[2-p-tolylethyl]-benzamide is associated with induction of DNA damage and inhibition of DNA replication.
    Du J, Miao C, Zhang X, Jeong IH, Son EM, You S, Lee BJ, Kim DK.
    Toxicol In Vitro; 2011 Dec 01; 25(8):1535-41. PubMed ID: 21621599
    [Abstract] [Full Text] [Related]

  • 35. Combination of the antivascular agent ZD6126 with hypoxic cytotoxin treatment, with reference to the effect on quiescent tumor cells and the dependency on p53 status of tumor cells.
    Masunaga S, Nagasawa H, Uto Y, Hori H, Ohnishi K, Takahashi A, Ohnishi T, Suzuki M, Nagata K, Kinashi Y, Ono K.
    Oncol Rep; 2005 Aug 01; 14(2):393-400. PubMed ID: 16012721
    [Abstract] [Full Text] [Related]

  • 36. Replication protein A as a potential regulator of DNA replication in cells exposed to hyperthermia.
    Wang Y, Perrault AR, Iliakis G.
    Radiat Res; 1998 Mar 01; 149(3):284-93. PubMed ID: 9496892
    [Abstract] [Full Text] [Related]

  • 37. Selective potentiation of the hypoxic cytotoxicity of tirapazamine by its 1-N-oxide metabolite SR 4317.
    Siim BG, Pruijn FB, Sturman JR, Hogg A, Hay MP, Brown JM, Wilson WR.
    Cancer Res; 2004 Jan 15; 64(2):736-42. PubMed ID: 14744792
    [Abstract] [Full Text] [Related]

  • 38. Cytotoxicity of Tirapazamine (3-Amino-1,2,4-benzotriazine-1,4-dioxide)-Induced DNA Damage in Chicken DT40 Cells.
    Moriwaki T, Okamoto S, Sasanuma H, Nagasawa H, Takeda S, Masunaga SI, Tano K.
    Chem Res Toxicol; 2017 Feb 20; 30(2):699-704. PubMed ID: 27943678
    [Abstract] [Full Text] [Related]

  • 39. The usefulness of continuous administration of hypoxic cytotoxin combined with mild temperature hyperthermia, with reference to effects on quiescent tumour cell populations.
    Masunaga S, Nagasawa H, Uto Y, Hori H, Suzuki M, Nagata K, Kinashi Y, Ono K.
    Int J Hyperthermia; 2005 Jun 20; 21(4):305-18. PubMed ID: 16019857
    [Abstract] [Full Text] [Related]

  • 40. Regulation of DNA replication in irradiated cells by trans-acting factors.
    Wang Y, Huq MS, Cheng X, Iliakis G.
    Radiat Res; 1995 May 20; 142(2):169-75. PubMed ID: 7724731
    [Abstract] [Full Text] [Related]

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