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281 related items for PubMed ID: 11454857
1. Side chain hydroxylations in bile acid biosynthesis catalyzed by CYP3A are markedly up-regulated in Cyp27-/- mice but not in cerebrotendinous xanthomatosis. Honda A, Salen G, Matsuzaki Y, Batta AK, Xu G, Leitersdorf E, Tint GS, Erickson SK, Tanaka N, Shefer S. J Biol Chem; 2001 Sep 14; 276(37):34579-85. PubMed ID: 11454857 [Abstract] [Full Text] [Related]
2. Differences in hepatic levels of intermediates in bile acid biosynthesis between Cyp27(-/-) mice and CTX. Honda A, Salen G, Matsuzaki Y, Batta AK, Xu G, Leitersdorf E, Tint GS, Erickson SK, Tanaka N, Shefer S. J Lipid Res; 2001 Feb 14; 42(2):291-300. PubMed ID: 11181760 [Abstract] [Full Text] [Related]
3. Identification of CYP3A4 as the major enzyme responsible for 25-hydroxylation of 5beta-cholestane-3alpha,7alpha,12alpha-triol in human liver microsomes. Furster C, Wikvall K. Biochim Biophys Acta; 1999 Jan 29; 1437(1):46-52. PubMed ID: 9931427 [Abstract] [Full Text] [Related]
4. Cholic acid biosynthesis: the enzymatic defect in cerebrotendinous xanthomatosis. Salen G, Shefer S, Cheng FW, Dayal B, Batta AK, Tint GS. J Clin Invest; 1979 Jan 29; 63(1):38-44. PubMed ID: 762246 [Abstract] [Full Text] [Related]
5. Anomalous enantioselectivity in the sharpless asymmetric dihydroxylation reaction of 24-nor-5beta-cholest-23-ene-3alpha,7alpha,12alpha-triol: synthesis of substrates for studies of cholesterol side-chain oxidation. Ertel NH, Dayal B, Rao K, Salen G. Lipids; 1999 Apr 29; 34(4):395-405. PubMed ID: 10443973 [Abstract] [Full Text] [Related]
6. Regulation of 25- and 27-hydroxylation side chain cleavage pathways for cholic acid biosynthesis in humans, rabbits, and mice. Assay of enzyme activities by high-resolution gas chromatography;-mass spectrometry. Honda A, Salen G, Shefer S, Matsuzaki Y, Xu G, Batta AK, Tint GS, Tanaka N. J Lipid Res; 2000 Mar 29; 41(3):442-51. PubMed ID: 10706592 [Abstract] [Full Text] [Related]
7. Metabolism of bile alcohols in the perfused rabbit liver. Cohen BI, Kuramoto T, Rothschild MA, Mosbach EH. J Biol Chem; 1976 May 10; 251(9):2709-15. PubMed ID: 1262339 [Abstract] [Full Text] [Related]
9. Biosynthesis of bile acids in cerebrotendinous xanthomatosis. Relationship of bile acid pool sizes and synthesis rates to hydroxylations at C-12, C-25, and C-26. Salen G, Shefer S, Tint GS, Nicolau G, Dayal B, Batta AK. J Clin Invest; 1985 Aug 10; 76(2):744-51. PubMed ID: 4031069 [Abstract] [Full Text] [Related]
10. Effect of biliary obstruction on 26-hydroxylation of C27-steroids in bile acid synthesis. Gustafsson J. J Lipid Res; 1978 Feb 10; 19(2):237-43. PubMed ID: 632686 [Abstract] [Full Text] [Related]
11. Biosynthesis of chenodeoxycholic acid in man: stereospecific side-chain hydroxylations of 5beta-cholestane-3alpha,7alpha-diol. Shefer S, Cheng FW, Batta AK, Dayal B, Tint GS, Salen G. J Clin Invest; 1978 Sep 10; 62(3):539-45. PubMed ID: 690184 [Abstract] [Full Text] [Related]
12. Structural and biosynthetic studies of a principal bile alcohol, 27-nor-5beta-cholestane-3alpha,7alpha,12alpha,24,25-pentol, in human urine. Une M, Takenaka S, Kuramoto T, Fujimura K, Hoshita T, Kihira K. J Lipid Res; 2000 Oct 10; 41(10):1562-7. PubMed ID: 11013297 [Abstract] [Full Text] [Related]
13. A 25-hydroxylation pathway of cholic acid biosynthesis in man and rat. Shefer S, Cheng FW, Dayal B, Hauser S, Tint GS, Salen G, Mosbach EH. J Clin Invest; 1976 Apr 10; 57(4):897-903. PubMed ID: 181403 [Abstract] [Full Text] [Related]
15. Bile alcohol metabolism in man. Conversion of 5beta-cholestane-3alpha, 7alpha,12alpha, 25-tetrol to cholic acid. Salen G, Shefer S, Setoguchi T, Mosbach EH. J Clin Invest; 1975 Jul 10; 56(1):226-31. PubMed ID: 1141434 [Abstract] [Full Text] [Related]
16. Markedly reduced bile acid synthesis but maintained levels of cholesterol and vitamin D metabolites in mice with disrupted sterol 27-hydroxylase gene. Rosen H, Reshef A, Maeda N, Lippoldt A, Shpizen S, Triger L, Eggertsen G, Björkhem I, Leitersdorf E. J Biol Chem; 1998 Jun 12; 273(24):14805-12. PubMed ID: 9614081 [Abstract] [Full Text] [Related]
17. Formation of bile acids in man: conversion of cholesterol into 5-beta-cholestane-3-alpha, 7-alpha, 12-alpha-triol in liver homogenates. Björkheim I, Danielsson H, Einarsson K, Johansson G. J Clin Invest; 1968 Jul 12; 47(7):1573-82. PubMed ID: 4385432 [Abstract] [Full Text] [Related]
18. Identification of bile acid precursors as endogenous ligands for the nuclear xenobiotic pregnane X receptor. Goodwin B, Gauthier KC, Umetani M, Watson MA, Lochansky MI, Collins JL, Leitersdorf E, Mangelsdorf DJ, Kliewer SA, Repa JJ. Proc Natl Acad Sci U S A; 2003 Jan 07; 100(1):223-8. PubMed ID: 12509506 [Abstract] [Full Text] [Related]
19. Identification of pentahydroxy bile alcohols in cerebrotendinous xanthomatosis: characterization of 5beta-cholestane-3alpha, 7alpha, 12alpha, 24xi, 25-pentol and 5beta-cholestane-3alpha, 7alpha, 12alpha, 23xi, 25-pentol. Shefer S, Dayal B, Tint GS, Salen G, Mosbach EH. J Lipid Res; 1975 Jul 07; 16(4):280-6. PubMed ID: 1141769 [Abstract] [Full Text] [Related]
20. Chemical synthesis of 5beta-cholestane-3alpha, 7alpha, 24, 25-tetrol and its metabolism in the perfused rabbit liver. Kuramoto T, Cohen BI, Rothschild MA, Donor DA, Mosbach EH. J Biol Chem; 1978 Jul 10; 253(13):4688-92. PubMed ID: 659442 [Abstract] [Full Text] [Related] Page: [Next] [New Search]