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260 related items for PubMed ID: 11457886

  • 21. PI3-kinase/Akt is constitutively active in primary acute myeloid leukaemia cells and regulates survival and chemoresistance via NF-kappaB, Mapkinase and p53 pathways.
    Grandage VL, Gale RE, Linch DC, Khwaja A.
    Leukemia; 2005 Apr; 19(4):586-94. PubMed ID: 15703783
    [Abstract] [Full Text] [Related]

  • 22. Expression of the NF-kappa B target gene X-ray-inducible immediate early response factor-1 short enhances TNF-alpha-induced hepatocyte apoptosis by inhibiting Akt activation.
    Osawa Y, Nagaki M, Banno Y, Brenner DA, Nozawa Y, Moriwaki H, Nakashima S.
    J Immunol; 2003 Apr 15; 170(8):4053-60. PubMed ID: 12682234
    [Abstract] [Full Text] [Related]

  • 23. C5b-9 terminal complement complex protects oligodendrocytes from death by regulating Bad through phosphatidylinositol 3-kinase/Akt pathway.
    Soane L, Cho HJ, Niculescu F, Rus H, Shin ML.
    J Immunol; 2001 Aug 15; 167(4):2305-11. PubMed ID: 11490019
    [Abstract] [Full Text] [Related]

  • 24. Activated AKT regulates NF-kappaB activation, p53 inhibition and cell survival in HTLV-1-transformed cells.
    Jeong SJ, Pise-Masison CA, Radonovich MF, Park HU, Brady JN.
    Oncogene; 2005 Oct 06; 24(44):6719-28. PubMed ID: 16007163
    [Abstract] [Full Text] [Related]

  • 25. Inhibition of phosphatidylinositol 3-kinase dephosphorylates BAD and promotes apoptosis in myeloid leukemias.
    Zhao S, Konopleva M, Cabreira-Hansen M, Xie Z, Hu W, Milella M, Estrov Z, Mills GB, Andreeff M.
    Leukemia; 2004 Feb 06; 18(2):267-75. PubMed ID: 14628071
    [Abstract] [Full Text] [Related]

  • 26. Monocyte survival factors induce Akt activation and suppress caspase-3.
    Goyal A, Wang Y, Graham MM, Doseff AI, Bhatt NY, Marsh CB.
    Am J Respir Cell Mol Biol; 2002 Feb 06; 26(2):224-30. PubMed ID: 11804874
    [Abstract] [Full Text] [Related]

  • 27. ets-2 is a target for an akt (Protein kinase B)/jun N-terminal kinase signaling pathway in macrophages of motheaten-viable mutant mice.
    Smith JL, Schaffner AE, Hofmeister JK, Hartman M, Wei G, Forsthoefel D, Hume DA, Ostrowski MC.
    Mol Cell Biol; 2000 Nov 06; 20(21):8026-34. PubMed ID: 11027273
    [Abstract] [Full Text] [Related]

  • 28. Akt protects mouse hepatocytes from TNF-alpha- and Fas-mediated apoptosis through NK-kappa B activation.
    Hatano E, Brenner DA.
    Am J Physiol Gastrointest Liver Physiol; 2001 Dec 06; 281(6):G1357-68. PubMed ID: 11705740
    [Abstract] [Full Text] [Related]

  • 29. Shp2E76K mutant confers cytokine-independent survival of TF-1 myeloid cells by up-regulating Bcl-XL.
    Ren Y, Chen Z, Chen L, Woods NT, Reuther GW, Cheng JQ, Wang HG, Wu J.
    J Biol Chem; 2007 Dec 14; 282(50):36463-73. PubMed ID: 17942397
    [Abstract] [Full Text] [Related]

  • 30. Activation of PI3-kinase/PKB contributes to delay in neutrophil apoptosis after thermal injury.
    Hu Z, Sayeed MM.
    Am J Physiol Cell Physiol; 2005 May 14; 288(5):C1171-8. PubMed ID: 15625305
    [Abstract] [Full Text] [Related]

  • 31. Long-term androgen-ablation causes increased resistance to PI3K/Akt pathway inhibition in prostate cancer cells.
    Pfeil K, Eder IE, Putz T, Ramoner R, Culig Z, Ueberall F, Bartsch G, Klocker H.
    Prostate; 2004 Feb 15; 58(3):259-68. PubMed ID: 14743465
    [Abstract] [Full Text] [Related]

  • 32. Inhibition of the phosphatidylinositol 3-kinase/Akt pathway sensitizes MDA-MB468 human breast cancer cells to cerulenin-induced apoptosis.
    Liu X, Shi Y, Giranda VL, Luo Y.
    Mol Cancer Ther; 2006 Mar 15; 5(3):494-501. PubMed ID: 16546963
    [Abstract] [Full Text] [Related]

  • 33. Granulocyte macrophage colony-stimulating factor signaling and proteasome inhibition delay neutrophil apoptosis by increasing the stability of Mcl-1.
    Derouet M, Thomas L, Cross A, Moots RJ, Edwards SW.
    J Biol Chem; 2004 Jun 25; 279(26):26915-21. PubMed ID: 15078892
    [Abstract] [Full Text] [Related]

  • 34. Role of Akt signaling in mitochondrial survival pathway triggered by hypoxic preconditioning.
    Uchiyama T, Engelman RM, Maulik N, Das DK.
    Circulation; 2004 Jun 22; 109(24):3042-9. PubMed ID: 15184284
    [Abstract] [Full Text] [Related]

  • 35. Overexpression of interferon-gamma-inducible GTPase inhibits coxsackievirus B3-induced apoptosis through the activation of the phosphatidylinositol 3-kinase/Akt pathway and inhibition of viral replication.
    Zhang HM, Yuan J, Cheung P, Luo H, Yanagawa B, Chau D, Stephan-Tozy N, Wong BW, Zhang J, Wilson JE, McManus BM, Yang D.
    J Biol Chem; 2003 Aug 29; 278(35):33011-9. PubMed ID: 12819192
    [Abstract] [Full Text] [Related]

  • 36. Potentiation of paclitaxel cytotoxicity in lung and esophageal cancer cells by pharmacologic inhibition of the phosphoinositide 3-kinase/protein kinase B (Akt)-mediated signaling pathway.
    Nguyen DM, Chen GA, Reddy R, Tsai W, Schrump WD, Cole G, Schrump DS.
    J Thorac Cardiovasc Surg; 2004 Feb 29; 127(2):365-75. PubMed ID: 14762343
    [Abstract] [Full Text] [Related]

  • 37. Constitutively active Akt1 protects HL60 leukemia cells from TRAIL-induced apoptosis through a mechanism involving NF-kappaB activation and cFLIP(L) up-regulation.
    Bortul R, Tazzari PL, Cappellini A, Tabellini G, Billi AM, Bareggi R, Manzoli L, Cocco L, Martelli AM.
    Leukemia; 2003 Feb 29; 17(2):379-89. PubMed ID: 12592338
    [Abstract] [Full Text] [Related]

  • 38. Phosphatidylinositol 3-kinase/Akt activity regulates c-FLIP expression in tumor cells.
    Panka DJ, Mano T, Suhara T, Walsh K, Mier JW.
    J Biol Chem; 2001 Mar 09; 276(10):6893-6. PubMed ID: 11145953
    [Abstract] [Full Text] [Related]

  • 39. Inhibition of phosphatidylinositol 3'-kinase/AKT signaling promotes apoptosis of primary effusion lymphoma cells.
    Uddin S, Hussain AR, Al-Hussein KA, Manogaran PS, Wickrema A, Gutierrez MI, Bhatia KG.
    Clin Cancer Res; 2005 Apr 15; 11(8):3102-8. PubMed ID: 15837766
    [Abstract] [Full Text] [Related]

  • 40. Regulation of Mcl-1 expression in rheumatoid arthritis synovial macrophages.
    Liu H, Huang Q, Shi B, Eksarko P, Temkin V, Pope RM.
    Arthritis Rheum; 2006 Oct 15; 54(10):3174-81. PubMed ID: 17009247
    [Abstract] [Full Text] [Related]

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