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155 related items for PubMed ID: 11463854
21. Identification and functional characterization of two novel activating thyrotropin receptor mutants in toxic thyroid follicular adenomas. Castro I, Lima L, Seoane R, Lado-Abeal J. Thyroid; 2009 Jun; 19(6):645-9. PubMed ID: 19499991 [Abstract] [Full Text] [Related]
22. Somatic mutations in the VI transmembrane segment of the thyrotropin receptor constitutively activate cAMP signalling in thyroid hyperfunctioning adenomas. Porcellini A, Ciullo I, Pannain S, Fenzi G, Avvedimento E. Oncogene; 1995 Sep 21; 11(6):1089-93. PubMed ID: 7566968 [Abstract] [Full Text] [Related]
23. A dominant negative Galphas mutant that prevents thyroid-stimulating hormone receptor activation of cAMP production and inositol 1,4,5-trisphosphate turnover: competition by different G proteins for activation by a common receptor. Cleator JH, Ravenell R, Kurtz DT, Hildebrandt JD. J Biol Chem; 2004 Aug 27; 279(35):36601-7. PubMed ID: 15234971 [Abstract] [Full Text] [Related]
24. Role of cysteine residues in the extracellular domain and exoplasmic loops of the transmembrane domain of the TSH receptor: effect of mutation to serine on TSH receptor activity and response to thyroid stimulating autoantibodies. Kosugi S, Ban T, Akamizu T, Kohn LD. Biochem Biophys Res Commun; 1992 Dec 30; 189(3):1754-62. PubMed ID: 1336379 [Abstract] [Full Text] [Related]
25. An aromatic environment in the vicinity of serine 281 is a structural requirement for thyrotropin receptor function. Jaeschke H, Neumann S, Kleinau G, Mueller S, Claus M, Krause G, Paschke R. Endocrinology; 2006 Apr 30; 147(4):1753-60. PubMed ID: 16410307 [Abstract] [Full Text] [Related]
26. The nematode leucine-rich repeat-containing, G protein-coupled receptor (LGR) protein homologous to vertebrate gonadotropin and thyrotropin receptors is constitutively active in mammalian cells. Kudo M, Chen T, Nakabayashi K, Hsu SY, Hsueh AJ. Mol Endocrinol; 2000 Feb 30; 14(2):272-84. PubMed ID: 10674399 [Abstract] [Full Text] [Related]
27. Structural determinants for g protein activation and selectivity in the second intracellular loop of the thyrotropin receptor. Neumann S, Krause G, Claus M, Paschke R. Endocrinology; 2005 Jan 30; 146(1):477-85. PubMed ID: 15498884 [Abstract] [Full Text] [Related]
28. A hydrophobic cluster in the center of the third extracellular loop is important for thyrotropin receptor signaling. Claus M, Jaeschke H, Kleinau G, Neumann S, Krause G, Paschke R. Endocrinology; 2005 Dec 30; 146(12):5197-203. PubMed ID: 16150909 [Abstract] [Full Text] [Related]
29. Identification of separate determinants on the thyrotropin receptor reactive with Graves' thyroid-stimulating antibodies and with thyroid-stimulating blocking antibodies in idiopathic myxedema: these determinants have no homologous sequence on gonadotropin receptors. Kosugi S, Ban T, Akamizu T, Kohn LD. Mol Endocrinol; 1992 Feb 30; 6(2):168-80. PubMed ID: 1349156 [Abstract] [Full Text] [Related]
30. [TSH receptors and signal transduction]. Kawakami Y, Fujita R, Okuda Y, Yamashita K. Nihon Rinsho; 1993 Oct 30; 51(10):2649-54. PubMed ID: 8254934 [Abstract] [Full Text] [Related]
31. Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas. Parma J, Duprez L, Van Sande J, Cochaux P, Gervy C, Mockel J, Dumont J, Vassart G. Nature; 1993 Oct 14; 365(6447):649-51. PubMed ID: 8413627 [Abstract] [Full Text] [Related]
32. Constitutive activation of the thyrotropin receptor by deletion of a portion of the extracellular domain. Zhang ML, Sugawa H, Kosugi S, Mori T. Biochem Biophys Res Commun; 1995 Jun 06; 211(1):205-10. PubMed ID: 7779086 [Abstract] [Full Text] [Related]
35. Role of the carboxyl-terminal half of the extracellular domain of the human thyrotropin receptor in signal transduction. Nagayama Y, Rapoport B. Endocrinology; 1992 Aug 06; 131(2):548-52. PubMed ID: 1322272 [Abstract] [Full Text] [Related]
37. The amino-terminal half of the cytoplasmic tail of the thyrotropin receptor is essential for full activities of receptor function. Kosugi S, Mori T. Biochem Biophys Res Commun; 1994 Apr 15; 200(1):401-7. PubMed ID: 8166712 [Abstract] [Full Text] [Related]
38. Functional characteristics of three new germline mutations of the thyrotropin receptor gene causing autosomal dominant toxic thyroid hyperplasia. Tonacchera M, Van Sande J, Cetani F, Swillens S, Schvartz C, Winiszewski P, Portmann L, Dumont JE, Vassart G, Parma J. J Clin Endocrinol Metab; 1996 Feb 15; 81(2):547-54. PubMed ID: 8636266 [Abstract] [Full Text] [Related]
39. Effects of mutations involving the highly conserved S281HCC motif in the extracellular domain of the thyrotropin (TSH) receptor on TSH binding and constitutive activity. Ho SC, Van Sande J, Lefort A, Vassart G, Costagliola S. Endocrinology; 2001 Jul 15; 142(7):2760-7. PubMed ID: 11415994 [Abstract] [Full Text] [Related]
40. A conserved tyrosine residue (Y601) in transmembrane domain 5 of the human thyrotropin receptor serves as a molecular switch to determine G-protein coupling. Biebermann H, Schöneberg T, Schulz A, Krause G, Grüters A, Schultz G, Gudermann T. FASEB J; 1998 Nov 15; 12(14):1461-71. PubMed ID: 9806755 [Abstract] [Full Text] [Related] Page: [Previous] [Next] [New Search]