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420 related items for PubMed ID: 11464949

  • 1. Superoxide dismutase-1 mutation-related neurotoxicity in familial amyotrophic lateral sclerosis.
    Shibata N, Hirano A, Yamamoto T, Kato Y, Kobayashi M.
    Amyotroph Lateral Scler Other Motor Neuron Disord; 2000 Jun; 1(3):143-61. PubMed ID: 11464949
    [Abstract] [Full Text] [Related]

  • 2. Transgenic mouse model for familial amyotrophic lateral sclerosis with superoxide dismutase-1 mutation.
    Shibata N.
    Neuropathology; 2001 Mar; 21(1):82-92. PubMed ID: 11304046
    [Abstract] [Full Text] [Related]

  • 3. Superoxide dismutase 1 mutants related to amyotrophic lateral sclerosis induce endoplasmic stress in neuro2a cells.
    Oh YK, Shin KS, Yuan J, Kang SJ.
    J Neurochem; 2008 Feb; 104(4):993-1005. PubMed ID: 18233996
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  • 4. Amyotrophic lateral sclerosis-related mutant superoxide dismutase 1 aggregates inhibit 14-3-3-mediated cell survival by sequestration into the JUNQ compartment.
    Park JH, Jang HR, Lee IY, Oh HK, Choi EJ, Rhim H, Kang S.
    Hum Mol Genet; 2017 Sep 15; 26(18):3615-3629. PubMed ID: 28666328
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  • 5. Cu/Zn superoxide dismutase (SOD1) mutations associated with familial amyotrophic lateral sclerosis (ALS) affect cellular free radical release in the presence of oxidative stress.
    Cookson MR, Menzies FM, Manning P, Eggett CJ, Figlewicz DA, McNeil CJ, Shaw PJ.
    Amyotroph Lateral Scler Other Motor Neuron Disord; 2002 Jun 15; 3(2):75-85. PubMed ID: 12215229
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  • 6. Increased mitochondrial antioxidative activity or decreased oxygen free radical propagation prevent mutant SOD1-mediated motor neuron cell death and increase amyotrophic lateral sclerosis-like transgenic mouse survival.
    Liu R, Li B, Flanagan SW, Oberley LW, Gozal D, Qiu M.
    J Neurochem; 2002 Feb 15; 80(3):488-500. PubMed ID: 11905995
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  • 7. Elevated free nitrotyrosine levels, but not protein-bound nitrotyrosine or hydroxyl radicals, throughout amyotrophic lateral sclerosis (ALS)-like disease implicate tyrosine nitration as an aberrant in vivo property of one familial ALS-linked superoxide dismutase 1 mutant.
    Bruijn LI, Beal MF, Becher MW, Schulz JB, Wong PC, Price DL, Cleveland DW.
    Proc Natl Acad Sci U S A; 1997 Jul 08; 94(14):7606-11. PubMed ID: 9207139
    [Abstract] [Full Text] [Related]

  • 8. Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mutant SOD1.
    Jaarsma D, Haasdijk ED, Grashorn JA, Hawkins R, van Duijn W, Verspaget HW, London J, Holstege JC.
    Neurobiol Dis; 2000 Dec 08; 7(6 Pt B):623-43. PubMed ID: 11114261
    [Abstract] [Full Text] [Related]

  • 9. Disulfide bond mediates aggregation, toxicity, and ubiquitylation of familial amyotrophic lateral sclerosis-linked mutant SOD1.
    Niwa J, Yamada S, Ishigaki S, Sone J, Takahashi M, Katsuno M, Tanaka F, Doyu M, Sobue G.
    J Biol Chem; 2007 Sep 21; 282(38):28087-95. PubMed ID: 17666395
    [Abstract] [Full Text] [Related]

  • 10. SOD1 in neurotoxicity and its controversial roles in SOD1 mutation-negative ALS.
    Hayashi Y, Homma K, Ichijo H.
    Adv Biol Regul; 2016 Jan 21; 60():95-104. PubMed ID: 26563614
    [Abstract] [Full Text] [Related]

  • 11. Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations.
    Mackenzie IR, Bigio EH, Ince PG, Geser F, Neumann M, Cairns NJ, Kwong LK, Forman MS, Ravits J, Stewart H, Eisen A, McClusky L, Kretzschmar HA, Monoranu CM, Highley JR, Kirby J, Siddique T, Shaw PJ, Lee VM, Trojanowski JQ.
    Ann Neurol; 2007 May 21; 61(5):427-34. PubMed ID: 17469116
    [Abstract] [Full Text] [Related]

  • 12. Delayed disease onset and extended survival in the SOD1G93A rat model of amyotrophic lateral sclerosis after suppression of mutant SOD1 in the motor cortex.
    Thomsen GM, Gowing G, Latter J, Chen M, Vit JP, Staggenborg K, Avalos P, Alkaslasi M, Ferraiuolo L, Likhite S, Kaspar BK, Svendsen CN.
    J Neurosci; 2014 Nov 19; 34(47):15587-600. PubMed ID: 25411487
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  • 18. Progressive impairment of CaV1.1 function in the skeletal muscle of mice expressing a mutant type 1 Cu/Zn superoxide dismutase (G93A) linked to amyotrophic lateral sclerosis.
    Beqollari D, Romberg CF, Dobrowolny G, Martini M, Voss AA, Musarò A, Bannister RA.
    Skelet Muscle; 2016 Nov 19; 6():24. PubMed ID: 27340545
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  • 20. Lack of involvement of neuronal nitric oxide synthase in the pathogenesis of a transgenic mouse model of familial amyotrophic lateral sclerosis.
    Facchinetti F, Sasaki M, Cutting FB, Zhai P, MacDonald JE, Reif D, Beal MF, Huang PL, Dawson TM, Gurney ME, Dawson VL.
    Neuroscience; 1999 Nov 19; 90(4):1483-92. PubMed ID: 10338314
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