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739 related items for PubMed ID: 11471548

  • 1. Role of transcription factor Nrf2 in the induction of hepatic phase 2 and antioxidative enzymes in vivo by the cancer chemoprotective agent, 3H-1, 2-dimethiole-3-thione.
    Kwak MK, Itoh K, Yamamoto M, Sutter TR, Kensler TW.
    Mol Med; 2001 Feb; 7(2):135-45. PubMed ID: 11471548
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  • 2. Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice.
    Ramos-Gomez M, Kwak MK, Dolan PM, Itoh K, Yamamoto M, Talalay P, Kensler TW.
    Proc Natl Acad Sci U S A; 2001 Mar 13; 98(6):3410-5. PubMed ID: 11248092
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  • 3. Role of Nrf2 signaling in regulation of antioxidants and phase 2 enzymes in cardiac fibroblasts: protection against reactive oxygen and nitrogen species-induced cell injury.
    Zhu H, Itoh K, Yamamoto M, Zweier JL, Li Y.
    FEBS Lett; 2005 Jun 06; 579(14):3029-36. PubMed ID: 15896789
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  • 4. Enhanced expression of the transcription factor Nrf2 by cancer chemopreventive agents: role of antioxidant response element-like sequences in the nrf2 promoter.
    Kwak MK, Itoh K, Yamamoto M, Kensler TW.
    Mol Cell Biol; 2002 May 06; 22(9):2883-92. PubMed ID: 11940647
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  • 5. The Cap'n'Collar basic leucine zipper transcription factor Nrf2 (NF-E2 p45-related factor 2) controls both constitutive and inducible expression of intestinal detoxification and glutathione biosynthetic enzymes.
    McMahon M, Itoh K, Yamamoto M, Chanas SA, Henderson CJ, McLellan LI, Wolf CR, Cavin C, Hayes JD.
    Cancer Res; 2001 Apr 15; 61(8):3299-307. PubMed ID: 11309284
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  • 6. Evaluation of the cancer chemopreventive potency of dithiolethione analogs of oltipraz.
    Roebuck BD, Curphey TJ, Li Y, Baumgartner KJ, Bodreddigari S, Yan J, Gange SJ, Kensler TW, Sutter TR.
    Carcinogenesis; 2003 Dec 15; 24(12):1919-28. PubMed ID: 14555609
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  • 8. Induction of Nrf2-regulated genes by 3H-1, 2-dithiole-3-thione through the ERK signaling pathway in murine keratinocytes.
    Manandhar S, Cho JM, Kim JA, Kensler TW, Kwak MK.
    Eur J Pharmacol; 2007 Dec 22; 577(1-3):17-27. PubMed ID: 17854798
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  • 10. Isolation of cDNAs representing dithiolethione-responsive genes.
    Primiano T, Gastel JA, Kensler TW, Sutter TR.
    Carcinogenesis; 1996 Nov 22; 17(11):2297-303. PubMed ID: 8968041
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  • 11. Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival.
    Kwak MK, Wakabayashi N, Itoh K, Motohashi H, Yamamoto M, Kensler TW.
    J Biol Chem; 2003 Mar 07; 278(10):8135-45. PubMed ID: 12506115
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  • 12. Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray.
    Thimmulappa RK, Mai KH, Srisuma S, Kensler TW, Yamamoto M, Biswal S.
    Cancer Res; 2002 Sep 15; 62(18):5196-203. PubMed ID: 12234984
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  • 13. Chemoprotective 3H-1,2-dithiole-3-thione induces antioxidant genes in vivo.
    Otieno MA, Kensler TW, Guyton KZ.
    Free Radic Biol Med; 2000 Mar 15; 28(6):944-52. PubMed ID: 10802226
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  • 14. Nrf2 mediates the induction of ferritin H in response to xenobiotics and cancer chemopreventive dithiolethiones.
    Pietsch EC, Chan JY, Torti FM, Torti SV.
    J Biol Chem; 2003 Jan 24; 278(4):2361-9. PubMed ID: 12435735
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  • 18. Potent inhibition of aflatoxin-induced hepatic tumorigenesis by the monofunctional enzyme inducer 1,2-dithiole-3-thione.
    Kensler TW, Groopman JD, Eaton DL, Curphey TJ, Roebuck BD.
    Carcinogenesis; 1992 Jan 24; 13(1):95-100. PubMed ID: 1346373
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  • 19. Cruciferous dithiolethione-mediated coordinated induction of total cellular and mitochondrial antioxidants and phase 2 enzymes in human primary cardiomyocytes: cytoprotection against oxidative/electrophilic stress and doxorubicin toxicity.
    Zhu H, Jia Z, Zhou K, Misra HP, Santo A, Gabrielson KL, Li Y.
    Exp Biol Med (Maywood); 2009 Apr 24; 234(4):418-29. PubMed ID: 19176875
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  • 20. Antioxidants and phase 2 enzymes in macrophages: regulation by Nrf2 signaling and protection against oxidative and electrophilic stress.
    Zhu H, Jia Z, Zhang L, Yamamoto M, Misra HP, Trush MA, Li Y.
    Exp Biol Med (Maywood); 2008 Apr 24; 233(4):463-74. PubMed ID: 18367636
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