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396 related items for PubMed ID: 11485552

  • 1. Multiple adaptive mechanisms affect asparagine synthetase substrate availability in asparaginase-resistant MOLT-4 human leukaemia cells.
    Aslanian AM, Kilberg MS.
    Biochem J; 2001 Aug 15; 358(Pt 1):59-67. PubMed ID: 11485552
    [Abstract] [Full Text] [Related]

  • 2. Asparagine synthetase expression alone is sufficient to induce l-asparaginase resistance in MOLT-4 human leukaemia cells.
    Aslanian AM, Fletcher BS, Kilberg MS.
    Biochem J; 2001 Jul 01; 357(Pt 1):321-8. PubMed ID: 11415466
    [Abstract] [Full Text] [Related]

  • 3. Inhibition of glutamine synthetase triggers apoptosis in asparaginase-resistant cells.
    Rotoli BM, Uggeri J, Dall'Asta V, Visigalli R, Barilli A, Gatti R, Orlandini G, Gazzola GC, Bussolati O.
    Cell Physiol Biochem; 2005 Jul 01; 15(6):281-92. PubMed ID: 16037693
    [Abstract] [Full Text] [Related]

  • 4. Correlation between asparaginase sensitivity and asparagine synthetase protein content, but not mRNA, in acute lymphoblastic leukemia cell lines.
    Su N, Pan YX, Zhou M, Harvey RC, Hunger SP, Kilberg MS.
    Pediatr Blood Cancer; 2008 Feb 01; 50(2):274-9. PubMed ID: 17514734
    [Abstract] [Full Text] [Related]

  • 5. Glutaminase Activity of L-Asparaginase Contributes to Durable Preclinical Activity against Acute Lymphoblastic Leukemia.
    Chan WK, Horvath TD, Tan L, Link T, Harutyunyan KG, Pontikos MA, Anishkin A, Du D, Martin LA, Yin E, Rempe SB, Sukharev S, Konopleva M, Weinstein JN, Lorenzi PL.
    Mol Cancer Ther; 2019 Sep 01; 18(9):1587-1592. PubMed ID: 31209181
    [Abstract] [Full Text] [Related]

  • 6. Asparagine depletion potentiates the cytotoxic effect of chemotherapy against brain tumors.
    Panosyan EH, Wang Y, Xia P, Lee WN, Pak Y, Laks DR, Lin HJ, Moore TB, Cloughesy TF, Kornblum HI, Lasky JL.
    Mol Cancer Res; 2014 May 01; 12(5):694-702. PubMed ID: 24505127
    [Abstract] [Full Text] [Related]

  • 7. Amino acid control of asparagine synthetase: relation to asparaginase resistance in human leukemia cells.
    Hutson RG, Kitoh T, Moraga Amador DA, Cosic S, Schuster SM, Kilberg MS.
    Am J Physiol; 1997 May 01; 272(5 Pt 1):C1691-9. PubMed ID: 9176161
    [Abstract] [Full Text] [Related]

  • 8. Differential mechanisms of asparaginase resistance in B-type acute lymphoblastic leukemia and malignant natural killer cell lines.
    Chien WW, Le Beux C, Rachinel N, Julien M, Lacroix CE, Allas S, Sahakian P, Cornut-Thibaut A, Lionnard L, Kucharczak J, Aouacheria A, Abribat T, Salles G.
    Sci Rep; 2015 Jan 28; 5():8068. PubMed ID: 25626693
    [Abstract] [Full Text] [Related]

  • 9. A sulfoximine-based inhibitor of human asparagine synthetase kills L-asparaginase-resistant leukemia cells.
    Ikeuchi H, Ahn YM, Otokawa T, Watanabe B, Hegazy L, Hiratake J, Richards NG.
    Bioorg Med Chem; 2012 Oct 01; 20(19):5915-27. PubMed ID: 22951255
    [Abstract] [Full Text] [Related]

  • 10. Deamination of glutamine is a prerequisite for optimal asparagine deamination by asparaginases in vivo (CCG-1961).
    Panosyan EH, Grigoryan RS, Avramis IA, Seibel NL, Gaynon PS, Siegel SE, Fingert HJ, Avramis VI.
    Anticancer Res; 2004 Oct 01; 24(2C):1121-5. PubMed ID: 15154634
    [Abstract] [Full Text] [Related]

  • 11. Immobilization of L-asparaginase into a biocompatible poly(ethylene glycol)-albumin hydrogel: evaluation of performance in vivo.
    Jean-François J, D'Urso EM, Fortier G.
    Biotechnol Appl Biochem; 1997 Dec 01; 26(3):203-12. PubMed ID: 9428158
    [Abstract] [Full Text] [Related]

  • 12. The inhibition of glutamine synthetase sensitizes human sarcoma cells to L-asparaginase.
    Tardito S, Uggeri J, Bozzetti C, Bianchi MG, Rotoli BM, Franchi-Gazzola R, Gazzola GC, Gatti R, Bussolati O.
    Cancer Chemother Pharmacol; 2007 Oct 01; 60(5):751-8. PubMed ID: 17256128
    [Abstract] [Full Text] [Related]

  • 13. L-Asparaginase and inhibitors of glutamine synthetase disclose glutamine addiction of β-catenin-mutated human hepatocellular carcinoma cells.
    Tardito S, Chiu M, Uggeri J, Zerbini A, Da Ros F, Dall'Asta V, Missale G, Bussolati O.
    Curr Cancer Drug Targets; 2011 Oct 01; 11(8):929-43. PubMed ID: 21834755
    [Abstract] [Full Text] [Related]

  • 14. A clinically attainable dose of L-asparaginase targets glutamine addiction in lymphoid cell lines.
    Sugimoto K, Suzuki HI, Fujimura T, Ono A, Kaga N, Isobe Y, Sasaki M, Taka H, Miyazono K, Komatsu N.
    Cancer Sci; 2015 Nov 01; 106(11):1534-43. PubMed ID: 26331698
    [Abstract] [Full Text] [Related]

  • 15. Biochemical characterization of U937 cells resistant to L-asparaginase: the role of asparagine synthetase.
    Kiriyama Y, Kubota M, Takimoto T, Kitoh T, Tanizawa A, Akiyama Y, Mikawa H.
    Leukemia; 1989 Apr 01; 3(4):294-7. PubMed ID: 2564453
    [Abstract] [Full Text] [Related]

  • 16. Evaluation of the asparagine synthetase level in leukemia cells by monoclonal antibodies.
    Kusano-Arai O, Iwanari H, Mochizuki Y, Nakata H, Kodama T, Kitoh T, Hamakubo T.
    Hybridoma (Larchmt); 2012 Oct 01; 31(5):325-32. PubMed ID: 23098298
    [Abstract] [Full Text] [Related]

  • 17. Insight into the mechanism of asparaginase-induced depletion of antithrombin III in treatment of childhood acute lymphoblastic leukemia.
    Bushman JE, Palmieri D, Whinna HC, Church FC.
    Leuk Res; 2000 Jul 01; 24(7):559-65. PubMed ID: 10867129
    [Abstract] [Full Text] [Related]

  • 18. The synergism of 6-mercaptopurine plus cytosine arabinoside followed by PEG-asparaginase in human leukemia cell lines (CCRF/CEM/0 and (CCRF/CEM/ara-C/7A) is due to increased cellular apoptosis.
    Nandy P, Periclou AP, Avramis VI.
    Anticancer Res; 1998 Jul 01; 18(2A):727-37. PubMed ID: 9615712
    [Abstract] [Full Text] [Related]

  • 19. Asparagine depletion after pegylated E. coli asparaginase treatment and induction outcome in children with acute lymphoblastic leukemia in first bone marrow relapse: a Children's Oncology Group study (CCG-1941).
    Jarrar M, Gaynon PS, Periclou AP, Fu C, Harris RE, Stram D, Altman A, Bostrom B, Breneman J, Steele D, Trigg M, Zipf T, Avramis VI.
    Pediatr Blood Cancer; 2006 Aug 01; 47(2):141-6. PubMed ID: 16425271
    [Abstract] [Full Text] [Related]

  • 20. Possible mechanism of metabolic and drug resistance with L-asparaginase therapy in childhood leukaemia.
    Zhou R, Liang T, Li T, Huang J, Chen C.
    Front Oncol; 2023 Aug 01; 13():1070069. PubMed ID: 36816964
    [Abstract] [Full Text] [Related]

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