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220 related items for PubMed ID: 11487572

  • 1. SCA7 mouse models show selective stabilization of mutant ataxin-7 and similar cellular responses in different neuronal cell types.
    Yvert G, Lindenberg KS, Devys D, Helmlinger D, Landwehrmeyer GB, Mandel JL.
    Hum Mol Genet; 2001 Aug 01; 10(16):1679-92. PubMed ID: 11487572
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  • 2. Similarities between spinocerebellar ataxia type 7 (SCA7) cell models and human brain: proteins recruited in inclusions and activation of caspase-3.
    Zander C, Takahashi J, El Hachimi KH, Fujigasaki H, Albanese V, Lebre AS, Stevanin G, Duyckaerts C, Brice A.
    Hum Mol Genet; 2001 Oct 15; 10(22):2569-79. PubMed ID: 11709544
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  • 4. Expanded polyglutamines induce neurodegeneration and trans-neuronal alterations in cerebellum and retina of SCA7 transgenic mice.
    Yvert G, Lindenberg KS, Picaud S, Landwehrmeyer GB, Sahel JA, Mandel JL.
    Hum Mol Genet; 2000 Oct 12; 9(17):2491-506. PubMed ID: 11030754
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  • 6. SCA7 knockin mice model human SCA7 and reveal gradual accumulation of mutant ataxin-7 in neurons and abnormalities in short-term plasticity.
    Yoo SY, Pennesi ME, Weeber EJ, Xu B, Atkinson R, Chen S, Armstrong DL, Wu SM, Sweatt JD, Zoghbi HY.
    Neuron; 2003 Feb 06; 37(3):383-401. PubMed ID: 12575948
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  • 8. A conditional pan-neuronal Drosophila model of spinocerebellar ataxia 7 with a reversible adult phenotype suitable for identifying modifier genes.
    Latouche M, Lasbleiz C, Martin E, Monnier V, Debeir T, Mouatt-Prigent A, Muriel MP, Morel L, Ruberg M, Brice A, Stevanin G, Tricoire H.
    J Neurosci; 2007 Mar 07; 27(10):2483-92. PubMed ID: 17344386
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  • 9. Polyglutamine-expanded ataxin-7 promotes non-cell-autonomous purkinje cell degeneration and displays proteolytic cleavage in ataxic transgenic mice.
    Garden GA, Libby RT, Fu YH, Kinoshita Y, Huang J, Possin DE, Smith AC, Martinez RA, Fine GC, Grote SK, Ware CB, Einum DD, Morrison RS, Ptacek LJ, Sopher BL, La Spada AR.
    J Neurosci; 2002 Jun 15; 22(12):4897-905. PubMed ID: 12077187
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  • 10. Autophagy: polyQ toxic fragment turnover.
    Duncan C, Papanikolaou T, Ellerby LM.
    Autophagy; 2010 Feb 15; 6(2):312-4. PubMed ID: 20104018
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  • 11. Polyglutamine-expanded ataxin-7 upregulates Bax expression by activating p53 in cerebellar and inferior olivary neurons.
    Wang HL, Chou AH, Lin AC, Chen SY, Weng YH, Yeh TH.
    Exp Neurol; 2010 Aug 15; 224(2):486-94. PubMed ID: 20546728
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  • 12. Posttranslational modification of ataxin-7 at lysine 257 prevents autophagy-mediated turnover of an N-terminal caspase-7 cleavage fragment.
    Mookerjee S, Papanikolaou T, Guyenet SJ, Sampath V, Lin A, Vitelli C, DeGiacomo F, Sopher BL, Chen SF, La Spada AR, Ellerby LM.
    J Neurosci; 2009 Dec 02; 29(48):15134-44. PubMed ID: 19955365
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  • 13. The autophagy/lysosome pathway is impaired in SCA7 patients and SCA7 knock-in mice.
    Alves S, Cormier-Dequaire F, Marinello M, Marais T, Muriel MP, Beaumatin F, Charbonnier-Beaupel F, Tahiri K, Seilhean D, El Hachimi K, Ruberg M, Stevanin G, Barkats M, den Dunnen W, Priault M, Brice A, Durr A, Corvol JC, Sittler A.
    Acta Neuropathol; 2014 Nov 02; 128(5):705-22. PubMed ID: 24859968
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  • 15. Molecular pathogenesis and cellular pathology of spinocerebellar ataxia type 7 neurodegeneration.
    Garden GA, La Spada AR.
    Cerebellum; 2008 Nov 02; 7(2):138-49. PubMed ID: 18418675
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  • 16. Association of ataxin-7 with the proteasome subunit S4 of the 19S regulatory complex.
    Matilla A, Gorbea C, Einum DD, Townsend J, Michalik A, van Broeckhoven C, Jensen CC, Murphy KJ, Ptácek LJ, Fu YH.
    Hum Mol Genet; 2001 Nov 15; 10(24):2821-31. PubMed ID: 11734547
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  • 17. Interferon β induces clearance of mutant ataxin 7 and improves locomotion in SCA7 knock-in mice.
    Chort A, Alves S, Marinello M, Dufresnois B, Dornbierer JG, Tesson C, Latouche M, Baker DP, Barkats M, El Hachimi KH, Ruberg M, Janer A, Stevanin G, Brice A, Sittler A.
    Brain; 2013 Jun 15; 136(Pt 6):1732-45. PubMed ID: 23518714
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  • 18. H1152 promotes the degradation of polyglutamine-expanded ataxin-3 or ataxin-7 independently of its ROCK-inhibiting effect and ameliorates mutant ataxin-3-induced neurodegeneration in the SCA3 transgenic mouse.
    Wang HL, Hu SH, Chou AH, Wang SS, Weng YH, Yeh TH.
    Neuropharmacology; 2013 Jul 15; 70():1-11. PubMed ID: 23347954
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  • 19. SUMOylation by SUMO2 is implicated in the degradation of misfolded ataxin-7 via RNF4 in SCA7 models.
    Marinello M, Werner A, Giannone M, Tahiri K, Alves S, Tesson C, den Dunnen W, Seeler JS, Brice A, Sittler A.
    Dis Model Mech; 2019 Jan 11; 12(1):. PubMed ID: 30559154
    [Abstract] [Full Text] [Related]

  • 20. Interference of Crx-dependent transcription by ataxin-7 involves interaction between the glutamine regions and requires the ataxin-7 carboxy-terminal region for nuclear localization.
    Chen S, Peng GH, Wang X, Smith AC, Grote SK, Sopher BL, La Spada AR.
    Hum Mol Genet; 2004 Jan 01; 13(1):53-67. PubMed ID: 14613968
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