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4. Epidermal growth factor receptor internalization through clathrin-coated pits requires Cbl RING finger and proline-rich domains but not receptor polyubiquitylation. Jiang X, Sorkin A. Traffic; 2003 Aug; 4(8):529-43. PubMed ID: 12839496 [Abstract] [Full Text] [Related]
5. Cbl-dependent ubiquitination is required for progression of EGF receptors into clathrin-coated pits. Stang E, Blystad FD, Kazazic M, Bertelsen V, Brodahl T, Raiborg C, Stenmark H, Madshus IH. Mol Biol Cell; 2004 Aug; 15(8):3591-604. PubMed ID: 15194809 [Abstract] [Full Text] [Related]
6. Cbl-mediated ubiquitinylation is required for lysosomal sorting of epidermal growth factor receptor but is dispensable for endocytosis. Duan L, Miura Y, Dimri M, Majumder B, Dodge IL, Reddi AL, Ghosh A, Fernandes N, Zhou P, Mullane-Robinson K, Rao N, Donoghue S, Rogers RA, Bowtell D, Naramura M, Gu H, Band V, Band H. J Biol Chem; 2003 Aug 01; 278(31):28950-60. PubMed ID: 12754251 [Abstract] [Full Text] [Related]
7. Both clathrin-positive and -negative coats are involved in endosomal sorting of the EGF receptor. Myromslien FD, Grøvdal LM, Raiborg C, Stenmark H, Madshus IH, Stang E. Exp Cell Res; 2006 Oct 01; 312(16):3036-48. PubMed ID: 16859684 [Abstract] [Full Text] [Related]
8. Ubc4/5 and c-Cbl continue to ubiquitinate EGF receptor after internalization to facilitate polyubiquitination and degradation. Umebayashi K, Stenmark H, Yoshimori T. Mol Biol Cell; 2008 Aug 01; 19(8):3454-62. PubMed ID: 18508924 [Abstract] [Full Text] [Related]
11. Sprouty fine-tunes EGF signaling through interlinked positive and negative feedback loops. Rubin C, Litvak V, Medvedovsky H, Zwang Y, Lev S, Yarden Y. Curr Biol; 2003 Feb 18; 13(4):297-307. PubMed ID: 12593795 [Abstract] [Full Text] [Related]
12. c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor. Levkowitz G, Waterman H, Zamir E, Kam Z, Oved S, Langdon WY, Beguinot L, Geiger B, Yarden Y. Genes Dev; 1998 Dec 01; 12(23):3663-74. PubMed ID: 9851973 [Abstract] [Full Text] [Related]
13. Growth factor receptor binding protein 2-mediated recruitment of the RING domain of Cbl to the epidermal growth factor receptor is essential and sufficient to support receptor endocytosis. Huang F, Sorkin A. Mol Biol Cell; 2005 Mar 01; 16(3):1268-81. PubMed ID: 15635092 [Abstract] [Full Text] [Related]
14. Sprouty2 attenuates epidermal growth factor receptor ubiquitylation and endocytosis, and consequently enhances Ras/ERK signalling. Wong ES, Fong CW, Lim J, Yusoff P, Low BC, Langdon WY, Guy GR. EMBO J; 2002 Sep 16; 21(18):4796-808. PubMed ID: 12234920 [Abstract] [Full Text] [Related]
15. Suppressors of T-cell receptor signaling Sts-1 and Sts-2 bind to Cbl and inhibit endocytosis of receptor tyrosine kinases. Kowanetz K, Crosetto N, Haglund K, Schmidt MHH, Heldin CH, Dikic I. J Biol Chem; 2004 Jul 30; 279(31):32786-95. PubMed ID: 15159412 [Abstract] [Full Text] [Related]
16. Re-localization of activated EGF receptor and its signal transducers to multivesicular compartments downstream of early endosomes in response to EGF. Oksvold MP, Skarpen E, Wierød L, Paulsen RE, Huitfeldt HS. Eur J Cell Biol; 2001 Apr 30; 80(4):285-94. PubMed ID: 11370743 [Abstract] [Full Text] [Related]
17. Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors. Soubeyran P, Kowanetz K, Szymkiewicz I, Langdon WY, Dikic I. Nature; 2002 Mar 14; 416(6877):183-7. PubMed ID: 11894095 [Abstract] [Full Text] [Related]
18. Inhibition of Src family kinases blocks epidermal growth factor (EGF)-induced activation of Akt, phosphorylation of c-Cbl, and ubiquitination of the EGF receptor. Kassenbrock CK, Hunter S, Garl P, Johnson GL, Anderson SM. J Biol Chem; 2002 Jul 12; 277(28):24967-75. PubMed ID: 11994282 [Abstract] [Full Text] [Related]
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