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Journal Abstract Search

142 related items for PubMed ID: 11495580

  • 1. Rationally based efficacy tuning of selective dopamine d4 receptor ligands leading to the complete antagonist 2-[4-(4-chlorophenyl)piperazin-1-ylmethyl]pyrazolo[1,5-a]pyridine (FAUC 213).
    Löber S, Hübner H, Utz W, Gmeiner P.
    J Med Chem; 2001 Aug 16; 44(17):2691-4. PubMed ID: 11495580
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  • 4. 2-[(4-phenylpiperazin-1-yl)methyl]imidazo(di)azines as selective D4-ligands. Induction of penile erection by 2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]imidazo[1,2-a]pyridine (PIP3EA), a potent and selective D4 partial agonist.
    Enguehard-Gueiffier C, Hübner H, El Hakmaoui A, Allouchi H, Gmeiner P, Argiolas A, Melis MR, Gueiffier A.
    J Med Chem; 2006 Jun 29; 49(13):3938-47. PubMed ID: 16789750
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  • 6. Di- and trisubstituted pyrazolo[1,5-a]pyridine derivatives: synthesis, dopamine receptor binding and ligand efficacy.
    Löber S, Aboul-Fadl T, Hübner H, Gmeiner P.
    Bioorg Med Chem Lett; 2002 Feb 25; 12(4):633-6. PubMed ID: 11844688
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  • 7. 6-(4-Benzylpiperazin-1-yl)benzodioxanes as selective ligands at cloned primate dopamine D(4) receptors.
    Hodgetts KJ, Kieltyka A, Brodbeck R, Tran JN, Wasley JW, Thurkauf A.
    Bioorg Med Chem; 2001 Dec 25; 9(12):3207-13. PubMed ID: 11711296
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  • 16. Certain 1,4-disubstituted aromatic piperidines and piperazines with extreme selectivity for the dopamine D4 receptor interact with a common receptor microdomain.
    Kortagere S, Gmeiner P, Weinstein H, Schetz JA.
    Mol Pharmacol; 2004 Dec 25; 66(6):1491-9. PubMed ID: 15448188
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  • 17. Pharmacophore-guided drug discovery investigations leading to bioactive 5-aminotetrahydropyrazolopyridines. Implications for the binding mode of heterocyclic dopamine D3 receptor agonists.
    Elsner J, Boeckler F, Heinemann FW, Hübner H, Gmeiner P.
    J Med Chem; 2005 Sep 08; 48(18):5771-9. PubMed ID: 16134944
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  • 20. Benzamide bioisosteres incorporating dihydroheteroazole substructures: EPC synthesis and SAR leading to a selective dopamine D4 receptor partial agonist (FAUC 179).
    Einsiedel J, Hübner H, Gmeiner P.
    Bioorg Med Chem Lett; 2001 Sep 17; 11(18):2533-6. PubMed ID: 11549463
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