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250 related items for PubMed ID: 11496955
1. Effect of mdr1a P-glycoprotein gene disruption, gender, and substrate concentration on brain uptake of selected compounds. Dagenais C, Zong J, Ducharme J, Pollack GM. Pharm Res; 2001 Jul; 18(7):957-63. PubMed ID: 11496955 [Abstract] [Full Text] [Related]
2. Variable modulation of opioid brain uptake by P-glycoprotein in mice. Dagenais C, Graff CL, Pollack GM. Biochem Pharmacol; 2004 Jan 15; 67(2):269-76. PubMed ID: 14698039 [Abstract] [Full Text] [Related]
3. Modulation of P-glycoprotein transport activity in the mouse blood-brain barrier by rifampin. Zong J, Pollack GM. J Pharmacol Exp Ther; 2003 Aug 15; 306(2):556-62. PubMed ID: 12721332 [Abstract] [Full Text] [Related]
4. Impact of P-glycoprotein on blood-retinal barrier permeability: comparison of blood-aqueous humor and blood-brain barrier using mdr1a knockout rats. Fujii S, Setoguchi C, Kawazu K, Hosoya K. Invest Ophthalmol Vis Sci; 2014 Jul 01; 55(7):4650-8. PubMed ID: 24985475 [Abstract] [Full Text] [Related]
5. In situ transport of vinblastine and selected P-glycoprotein substrates: implications for drug-drug interactions at the mouse blood-brain barrier. Cisternino S, Rousselle C, Debray M, Scherrmann JM. Pharm Res; 2004 Aug 01; 21(8):1382-9. PubMed ID: 15359572 [Abstract] [Full Text] [Related]
7. Quantitative evaluation of the impact of active efflux by p-glycoprotein and breast cancer resistance protein at the blood-brain barrier on the predictability of the unbound concentrations of drugs in the brain using cerebrospinal fluid concentration as a surrogate. Kodaira H, Kusuhara H, Fujita T, Ushiki J, Fuse E, Sugiyama Y. J Pharmacol Exp Ther; 2011 Dec 01; 339(3):935-44. PubMed ID: 21934030 [Abstract] [Full Text] [Related]
8. Interaction of nonpeptidic delta agonists with P-glycoprotein by in situ mouse brain perfusion: liquid chromatography-mass spectrometry analysis and internal standard strategy. Dagenais C, Ducharme J, Pollack GM. J Pharm Sci; 2002 Jan 01; 91(1):244-52. PubMed ID: 11782913 [Abstract] [Full Text] [Related]
9. Kinetic analysis of the cooperation of P-glycoprotein (P-gp/Abcb1) and breast cancer resistance protein (Bcrp/Abcg2) in limiting the brain and testis penetration of erlotinib, flavopiridol, and mitoxantrone. Kodaira H, Kusuhara H, Ushiki J, Fuse E, Sugiyama Y. J Pharmacol Exp Ther; 2010 Jun 01; 333(3):788-96. PubMed ID: 20304939 [Abstract] [Full Text] [Related]
10. Morphine antinociception is enhanced in mdr1a gene-deficient mice. Zong J, Pollack GM. Pharm Res; 2000 Jun 01; 17(6):749-53. PubMed ID: 10955852 [Abstract] [Full Text] [Related]
11. Regional differences in capillary density, perfusion rate, and P-glycoprotein activity: a quantitative analysis of regional drug exposure in the brain. Zhao R, Pollack GM. Biochem Pharmacol; 2009 Oct 15; 78(8):1052-9. PubMed ID: 19523457 [Abstract] [Full Text] [Related]
13. Evidence for an active transport of morphine-6-beta-d-glucuronide but not P-glycoprotein-mediated at the blood-brain barrier. Bourasset F, Cisternino S, Temsamani J, Scherrmann JM. J Neurochem; 2003 Sep 15; 86(6):1564-7. PubMed ID: 12950465 [Abstract] [Full Text] [Related]
15. Antinociceptive effects of morphine-6-glucuronide in homozygous MDR1a P-glycoprotein knockout and in wildtype mice in the hotplate test. Lötsch J, Tegeder I, Angst MS, Geisslinger G. Life Sci; 2000 May 05; 66(24):2393-403. PubMed ID: 10864101 [Abstract] [Full Text] [Related]