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208 related items for PubMed ID: 11498510

  • 1. Mutational analysis of the human vasoactive intestinal peptide receptor subtype VPAC(2): role of basic residues in the second transmembrane helix.
    Vertongen P, Solano RM, Perret J, Langer I, Robberecht P, Waelbroeck M.
    Br J Pharmacol; 2001 Aug; 133(8):1249-54. PubMed ID: 11498510
    [Abstract] [Full Text] [Related]

  • 2. Two tyrosine residues in the first transmembrane helix of the human vasoactive intestinal peptide receptors play a role in supporting the active conformation.
    Perret J, Vertongen P, Solano RM, Langer I, Cnudde J, Robberecht P, Waelbroeck M.
    Br J Pharmacol; 2002 Aug; 136(7):1042-8. PubMed ID: 12145104
    [Abstract] [Full Text] [Related]

  • 3. Two basic residues of the h-VPAC1 receptor second transmembrane helix are essential for ligand binding and signal transduction.
    Solano RM, Langer I, Perret J, Vertongen P, Juarranz MG, Robberecht P, Waelbroeck M.
    J Biol Chem; 2001 Jan 12; 276(2):1084-8. PubMed ID: 11013258
    [Abstract] [Full Text] [Related]

  • 4. Characterization of a novel VPAC(1) selective agonist and identification of the receptor domains implicated in the carboxyl-terminal peptide recognition.
    Van Rampelbergh J, Juarranz MG, Perret J, Bondue A, Solano RM, Delporte C, De Neef P, Robberecht P, Waelbroeck M.
    Br J Pharmacol; 2000 Jun 12; 130(4):819-26. PubMed ID: 10864888
    [Abstract] [Full Text] [Related]

  • 5. Ac His1 [D-Phe2, K15, R16, L27] VIP (3-7)/GRF (8-27)--a VPAC1 receptor antagonist--is an inverse agonist on two constitutively active truncated VPAC1 receptors.
    Vertongen P, Langlet C, Langer I, Gaspard N, Robberecht P.
    Peptides; 2004 Nov 12; 25(11):1943-9. PubMed ID: 15501526
    [Abstract] [Full Text] [Related]

  • 6. Elucidation of the vasoactive intestinal peptide pharmacophore for VPAC(2) receptors in human and rat and comparison to the pharmacophore for VPAC(1) receptors.
    Igarashi H, Ito T, Pradhan TK, Mantey SA, Hou W, Coy DH, Jensen RT.
    J Pharmacol Exp Ther; 2002 Nov 12; 303(2):445-60. PubMed ID: 12388623
    [Abstract] [Full Text] [Related]

  • 7. Asn229 in the third helix of VPAC1 receptor is essential for receptor activation but not for receptor phosphorylation and internalization: comparison with Asn216 in VPAC2 receptor.
    Nachtergael I, Gaspard N, Langlet C, Robberecht P, Langer I.
    Cell Signal; 2006 Dec 12; 18(12):2121-30. PubMed ID: 16650965
    [Abstract] [Full Text] [Related]

  • 8. Evidence for a direct interaction between the Thr11 residue of vasoactive intestinal polypeptide and Tyr184 located in the first extracellular loop of the VPAC2 receptor.
    Nachtergael I, Vertongen P, Langer I, Perret J, Robberecht P, Waelbroeck M.
    Biochem J; 2003 Mar 15; 370(Pt 3):1003-9. PubMed ID: 12475394
    [Abstract] [Full Text] [Related]

  • 9. Different vasoactive intestinal polypeptide receptor domains are involved in the selective recognition of two VPAC(2)-selective ligands.
    Juarranz MG, Van Rampelbergh J, Gourlet P, De Neef P, Cnudde J, Robberecht P, Waelbroeck M.
    Mol Pharmacol; 1999 Dec 15; 56(6):1280-7. PubMed ID: 10570056
    [Abstract] [Full Text] [Related]

  • 10. Vasoactive intestinal polypeptide receptor VPAC(1) subtype is predominant in rat prostate membranes.
    Juarranz MG, De Neef P, Robberecht P.
    Prostate; 1999 Sep 15; 41(1):1-6. PubMed ID: 10440869
    [Abstract] [Full Text] [Related]

  • 11. Effect of inactivating mutations on phosphorylation and internalization of the human VPAC2 receptor.
    Langer I, Langlet C, Robberecht P.
    J Mol Endocrinol; 2005 Apr 15; 34(2):405-14. PubMed ID: 15821106
    [Abstract] [Full Text] [Related]

  • 12. Identification of key residues for interaction of vasoactive intestinal peptide with human VPAC1 and VPAC2 receptors and development of a highly selective VPAC1 receptor agonist. Alanine scanning and molecular modeling of the peptide.
    Nicole P, Lins L, Rouyer-Fessard C, Drouot C, Fulcrand P, Thomas A, Couvineau A, Martinez J, Brasseur R, Laburthe M.
    J Biol Chem; 2000 Aug 04; 275(31):24003-12. PubMed ID: 10801840
    [Abstract] [Full Text] [Related]

  • 13. A small sequence in the third intracellular loop of the VPAC(1) receptor is responsible for its efficient coupling to the calcium effector.
    Langer I, Vertongen P, Perret J, Waelbroeck M, Robberecht P.
    Mol Endocrinol; 2002 May 04; 16(5):1089-96. PubMed ID: 11981043
    [Abstract] [Full Text] [Related]

  • 14. Development of selective agonists and antagonists for the human vasoactive intestinal polypeptide VPAC(2) receptor.
    Moreno D, Gourlet P, De Neef P, Cnudde J, Waelbroeck M, Robberecht P.
    Peptides; 2000 Oct 04; 21(10):1543-9. PubMed ID: 11068102
    [Abstract] [Full Text] [Related]

  • 15. Tryptophan 67 in the human VPAC(1) receptor: crucial role for VIP binding.
    Nicole P, Maoret JJ, Couvineau A, Momany FA, Laburthe M.
    Biochem Biophys Res Commun; 2000 Sep 24; 276(2):654-9. PubMed ID: 11027527
    [Abstract] [Full Text] [Related]

  • 16. Mutational analysis of the glucagon receptor: similarities with the vasoactive intestinal peptide (VIP)/pituitary adenylate cyclase-activating peptide (PACAP)/secretin receptors for recognition of the ligand's third residue.
    Perret J, Van Craenenbroeck M, Langer I, Vertongen P, Gregoire F, Robberecht P, Waelbroeck M.
    Biochem J; 2002 Mar 01; 362(Pt 2):389-94. PubMed ID: 11853547
    [Abstract] [Full Text] [Related]

  • 17. Identification of a VIP-specific receptor in guinea pig tenia coli.
    Teng BQ, Grider JR, Murthy KS.
    Am J Physiol Gastrointest Liver Physiol; 2001 Sep 01; 281(3):G718-25. PubMed ID: 11518684
    [Abstract] [Full Text] [Related]

  • 18. VIP activates G(s) and G(i3) in rat alveolar macrophages and G(s) in HEK293 cells transfected with the human VPAC(1) receptor.
    Shreeve SM, Sreedharan SP, Hacker MP, Gannon DE, Morgan MJ.
    Biochem Biophys Res Commun; 2000 Jun 16; 272(3):922-8. PubMed ID: 10860852
    [Abstract] [Full Text] [Related]

  • 19. Lysine 195 and aspartate 196 in the first extracellular loop of the VPAC1 receptor are essential for high affinity binding of agonists but not of antagonists.
    Langer I, Vertongen P, Perret J, Waelbroeck M, Robberecht P.
    Neuropharmacology; 2003 Jan 16; 44(1):125-31. PubMed ID: 12559130
    [Abstract] [Full Text] [Related]

  • 20. VPAC2 receptors mediate vasoactive intestinal peptide-induced neuroprotection against neonatal excitotoxic brain lesions in mice.
    Rangon CM, Goursaud S, Medja F, Lelièvre V, Mounien L, Husson I, Brabet P, Jégou S, Janet T, Gressens P.
    J Pharmacol Exp Ther; 2005 Aug 16; 314(2):745-52. PubMed ID: 15872042
    [Abstract] [Full Text] [Related]

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