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2. The 5' boundary of somatic hypermutation in a V kappa gene is in the leader intron. Rada C, González-Fernández A, Jarvis JM, Milstein C. Eur J Immunol; 1994 Jun; 24(6):1453-7. PubMed ID: 8206104 [Abstract] [Full Text] [Related]
3. The 5' hypermutation boundary of kappa chains is independent of local and neighbouring sequences and related to the distance from the initiation of transcription. Rada C, Yélamos J, Dean W, Milstein C. Eur J Immunol; 1997 Dec; 27(12):3115-20. PubMed ID: 9464795 [Abstract] [Full Text] [Related]
4. Somatic hypermutation of an immunoglobulin transgene in kappa transgenic mice. O'Brien RL, Brinster RL, Storb U. Nature; 1997 Dec; 326(6111):405-9. PubMed ID: 3104790 [Abstract] [Full Text] [Related]
5. Somatic hypermutation of Ig genes is affected differently by failures in apoptosis caused by disruption of Fas (lpr mutation) or by overexpression of Bcl-2. Mastache EF, Lindroth K, Fernández C, González-Fernández A. Scand J Immunol; 2006 Jun; 63(6):420-9. PubMed ID: 16764695 [Abstract] [Full Text] [Related]
6. Cell-cycle-regulated DNA double-stranded breaks in somatic hypermutation of immunoglobulin genes. Papavasiliou FN, Schatz DG. Nature; 2000 Nov 09; 408(6809):216-21. PubMed ID: 11089977 [Abstract] [Full Text] [Related]
7. Rearrangement of the human heavy chain variable region gene V3-23 in transgenic mice generates antibodies reactive with a range of antigens on the basis of VHCDR3 and residues intrinsic to the heavy chain variable region. Mageed RA, Harmer IJ, Wynn SL, Moyes SP, Maziak BB, Brüggemann M, MacKworth-Young CG. Clin Exp Immunol; 2001 Jan 09; 123(1):1-8. PubMed ID: 11167990 [Abstract] [Full Text] [Related]
8. Somatic hypermutation of an artificial test substrate within an Ig kappa transgene. Klotz EL, Hackett J, Storb U. J Immunol; 1998 Jul 15; 161(2):782-90. PubMed ID: 9670955 [Abstract] [Full Text] [Related]
9. Mapping the upstream boundary of somatic mutations in rearranged immunoglobulin transgenes and endogenous genes. Rogerson BJ. Mol Immunol; 1994 Feb 15; 31(2):83-98. PubMed ID: 8309480 [Abstract] [Full Text] [Related]
10. Insertion of 2 kb of bacteriophage DNA between an immunoglobulin promoter and leader exon stops somatic hypermutation in a kappa transgene. Winter DB, Sattar N, Mai JJ, Gearhart PJ. Mol Immunol; 1997 Apr 15; 34(5):359-66. PubMed ID: 9293769 [Abstract] [Full Text] [Related]
11. The human immunoglobulin loci introduced into mice: V (D) and J gene segment usage similar to that of adult humans. Gallo ML, Ivanov VE, Jakobovits A, Davis CG. Eur J Immunol; 2000 Feb 15; 30(2):534-40. PubMed ID: 10671209 [Abstract] [Full Text] [Related]
12. Targeting of non-Ig sequences in place of the V segment by somatic hypermutation. Yélamos J, Klix N, Goyenechea B, Lozano F, Chui YL, González Fernández A, Pannell R, Neuberger MS, Milstein C. Nature; 1995 Jul 20; 376(6537):225-9. PubMed ID: 7617031 [Abstract] [Full Text] [Related]
13. The targeting of somatic hypermutation. Jolly CJ, Wagner SD, Rada C, Klix N, Milstein C, Neuberger MS. Semin Immunol; 1996 Jun 20; 8(3):159-68. PubMed ID: 8738915 [Abstract] [Full Text] [Related]
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15. Characteristics of sequences around individual nucleotide substitutions in IgVH genes suggest different GC and AT mutators. Spencer J, Dunn M, Dunn-Walters DK. J Immunol; 1999 Jun 01; 162(11):6596-601. PubMed ID: 10352276 [Abstract] [Full Text] [Related]
16. Characterization of the cis-acting elements required for somatic hypermutation of murine antibody V genes using conventional transgenic and transgene homologous recombination approaches. Tumas-Brundage K, Vora KA, Giusti AM, Manser T. Semin Immunol; 1996 Jun 01; 8(3):141-50. PubMed ID: 8738913 [Abstract] [Full Text] [Related]