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PUBMED FOR HANDHELDS

Journal Abstract Search


219 related items for PubMed ID: 11522790

  • 1. A mutant form of JAB/SOCS1 augments the cytokine-induced JAK/STAT pathway by accelerating degradation of wild-type JAB/CIS family proteins through the SOCS-box.
    Hanada T, Yoshida T, Kinjyo I, Minoguchi S, Yasukawa H, Kato S, Mimata H, Nomura Y, Seki Y, Kubo M, Yoshimura A.
    J Biol Chem; 2001 Nov 02; 276(44):40746-54. PubMed ID: 11522790
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  • 2. CIS3/SOCS3/SSI3 plays a negative regulatory role in STAT3 activation and intestinal inflammation.
    Suzuki A, Hanada T, Mitsuyama K, Yoshida T, Kamizono S, Hoshino T, Kubo M, Yamashita A, Okabe M, Takeda K, Akira S, Matsumoto S, Toyonaga A, Sata M, Yoshimura A.
    J Exp Med; 2001 Feb 19; 193(4):471-81. PubMed ID: 11181699
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  • 3. Induction of JAB/SOCS-1/SSI-1 and CIS3/SOCS-3/SSI-3 is involved in gp130 resistance in cardiovascular system in rat treated with cardiotrophin-1 in vivo.
    Hamanaka I, Saito Y, Yasukawa H, Kishimoto I, Kuwahara K, Miyamoto Y, Harada M, Ogawa E, Kajiyama N, Takahashi N, Izumi T, Kawakami R, Masuda I, Yoshimura A, Nakao K.
    Circ Res; 2001 Apr 13; 88(7):727-32. PubMed ID: 11304496
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  • 4. The JAK-inhibitor, JAB/SOCS-1 selectively inhibits cytokine-induced, but not v-Src induced JAK-STAT activation.
    Iwamoto T, Senga T, Naito Y, Matsuda S, Miyake Y, Yoshimura A, Hamaguchi M.
    Oncogene; 2000 Sep 28; 19(41):4795-801. PubMed ID: 11032030
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  • 5. CIS3 and JAB have different regulatory roles in interleukin-6 mediated differentiation and STAT3 activation in M1 leukemia cells.
    Suzuki R, Sakamoto H, Yasukawa H, Masuhara M, Wakioka T, Sasaki A, Yuge K, Komiya S, Inoue A, Yoshimura A.
    Oncogene; 1998 Oct 29; 17(17):2271-8. PubMed ID: 9811457
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  • 9. A new protein containing an SH2 domain that inhibits JAK kinases.
    Endo TA, Masuhara M, Yokouchi M, Suzuki R, Sakamoto H, Mitsui K, Matsumoto A, Tanimura S, Ohtsubo M, Misawa H, Miyazaki T, Leonor N, Taniguchi T, Fujita T, Kanakura Y, Komiya S, Yoshimura A.
    Nature; 1997 Jun 26; 387(6636):921-4. PubMed ID: 9202126
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  • 10. Cytokine-inducible SH2 protein-3 (CIS3/SOCS3) inhibits Janus tyrosine kinase by binding through the N-terminal kinase inhibitory region as well as SH2 domain.
    Sasaki A, Yasukawa H, Suzuki A, Kamizono S, Syoda T, Kinjyo I, Sasaki M, Johnston JA, Yoshimura A.
    Genes Cells; 1999 Jun 26; 4(6):339-51. PubMed ID: 10421843
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  • 11. Negative regulation of cytokine signaling pathways.
    Yasukawa H, Sasaki A, Yoshimura A.
    Annu Rev Immunol; 2000 Jun 26; 18():143-64. PubMed ID: 10837055
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  • 12. SOCS proteins: negative regulators of cytokine signaling.
    Krebs DL, Hilton DJ.
    Stem Cells; 2001 Jun 26; 19(5):378-87. PubMed ID: 11553846
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  • 15. The janus kinase inhibitor, Jab/SOCS-1, is an interferon-gamma inducible gene and determines the sensitivity to interferons.
    Sakamoto H, Kinjyo I, Yoshimura A.
    Leuk Lymphoma; 2000 Jun 26; 38(1-2):49-58. PubMed ID: 10811447
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  • 18. Cloning and characterization of novel CIS family genes.
    Masuhara M, Sakamoto H, Matsumoto A, Suzuki R, Yasukawa H, Mitsui K, Wakioka T, Tanimura S, Sasaki A, Misawa H, Yokouchi M, Ohtsubo M, Yoshimura A.
    Biochem Biophys Res Commun; 1997 Oct 20; 239(2):439-46. PubMed ID: 9344848
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  • 19. SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity.
    Yoshikawa H, Matsubara K, Qian GS, Jackson P, Groopman JD, Manning JE, Harris CC, Herman JG.
    Nat Genet; 2001 May 20; 28(1):29-35. PubMed ID: 11326271
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  • 20. The SOCS box of SOCS-1 accelerates ubiquitin-dependent proteolysis of TEL-JAK2.
    Kamizono S, Hanada T, Yasukawa H, Minoguchi S, Kato R, Minoguchi M, Hattori K, Hatakeyama S, Yada M, Morita S, Kitamura T, Kato H, Nakayama Ki, Yoshimura A.
    J Biol Chem; 2001 Apr 20; 276(16):12530-8. PubMed ID: 11278610
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