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395 related items for PubMed ID: 11535817

  • 1. The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species.
    Ruefli AA, Ausserlechner MJ, Bernhard D, Sutton VR, Tainton KM, Kofler R, Smyth MJ, Johnstone RW.
    Proc Natl Acad Sci U S A; 2001 Sep 11; 98(19):10833-8. PubMed ID: 11535817
    [Abstract] [Full Text] [Related]

  • 2. Role of caspases, Bid, and p53 in the apoptotic response triggered by histone deacetylase inhibitors trichostatin-A (TSA) and suberoylanilide hydroxamic acid (SAHA).
    Henderson C, Mizzau M, Paroni G, Maestro R, Schneider C, Brancolini C.
    J Biol Chem; 2003 Apr 04; 278(14):12579-89. PubMed ID: 12556448
    [Abstract] [Full Text] [Related]

  • 3. Suberoylanilide hydroxamic acid (SAHA) overcomes multidrug resistance and induces cell death in P-glycoprotein-expressing cells.
    Ruefli AA, Bernhard D, Tainton KM, Kofler R, Smyth MJ, Johnstone RW.
    Int J Cancer; 2002 May 10; 99(2):292-8. PubMed ID: 11979447
    [Abstract] [Full Text] [Related]

  • 4. Cadmium induces apoptotic cell death in WI 38 cells via caspase-dependent Bid cleavage and calpain-mediated mitochondrial Bax cleavage by Bcl-2-independent pathway.
    Oh SH, Lee BH, Lim SC.
    Biochem Pharmacol; 2004 Nov 01; 68(9):1845-55. PubMed ID: 15450950
    [Abstract] [Full Text] [Related]

  • 5. Synergistic induction of mitochondrial damage and apoptosis in human leukemia cells by flavopiridol and the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA).
    Almenara J, Rosato R, Grant S.
    Leukemia; 2002 Jul 01; 16(7):1331-43. PubMed ID: 12094258
    [Abstract] [Full Text] [Related]

  • 6. Cleavage of BID during cytotoxic drug and UV radiation-induced apoptosis occurs downstream of the point of Bcl-2 action and is catalysed by caspase-3: a potential feedback loop for amplification of apoptosis-associated mitochondrial cytochrome c release.
    Slee EA, Keogh SA, Martin SJ.
    Cell Death Differ; 2000 Jun 01; 7(6):556-65. PubMed ID: 10822279
    [Abstract] [Full Text] [Related]

  • 7. c-Myc overexpression sensitizes Bim-mediated Bax activation for apoptosis induced by histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) through regulating Bcl-2/Bcl-xL expression.
    Jiang X, Tsang YH, Yu Q.
    Int J Biochem Cell Biol; 2007 Jun 01; 39(5):1016-25. PubMed ID: 17331788
    [Abstract] [Full Text] [Related]

  • 8. Combined treatment with Ad-hTRAIL and DTIC or SAHA is associated with increased mitochondrial-mediated apoptosis in human melanoma cell lines.
    Lillehammer T, Engesaeter BO, Prasmickaite L, Maelandsmo GM, Fodstad O, Engebraaten O.
    J Gene Med; 2007 Jun 01; 9(6):440-51. PubMed ID: 17410615
    [Abstract] [Full Text] [Related]

  • 9. Curcumin (diferuloylmethane) induces apoptosis through activation of caspase-8, BID cleavage and cytochrome c release: its suppression by ectopic expression of Bcl-2 and Bcl-xl.
    Anto RJ, Mukhopadhyay A, Denning K, Aggarwal BB.
    Carcinogenesis; 2002 Jan 01; 23(1):143-50. PubMed ID: 11756235
    [Abstract] [Full Text] [Related]

  • 10. Coadministration of histone deacetylase inhibitors and perifosine synergistically induces apoptosis in human leukemia cells through Akt and ERK1/2 inactivation and the generation of ceramide and reactive oxygen species.
    Rahmani M, Reese E, Dai Y, Bauer C, Payne SG, Dent P, Spiegel S, Grant S.
    Cancer Res; 2005 Mar 15; 65(6):2422-32. PubMed ID: 15781658
    [Abstract] [Full Text] [Related]

  • 11. The caspase-8/Bid/cytochrome c axis links signals from death receptors to mitochondrial reactive oxygen species production.
    Kim WS, Lee KS, Kim JH, Kim CK, Lee G, Choe J, Won MH, Kim TH, Jeoung D, Lee H, Kim JY, Ae Jeong M, Ha KS, Kwon YG, Kim YM.
    Free Radic Biol Med; 2017 Nov 15; 112():567-577. PubMed ID: 28888620
    [Abstract] [Full Text] [Related]

  • 12. Apoptotic and autophagic cell death induced by histone deacetylase inhibitors.
    Shao Y, Gao Z, Marks PA, Jiang X.
    Proc Natl Acad Sci U S A; 2004 Dec 28; 101(52):18030-5. PubMed ID: 15596714
    [Abstract] [Full Text] [Related]

  • 13. Induction of apoptosis in human hepatoblastoma cells by tetrandrine via caspase-dependent Bid cleavage and cytochrome c release.
    Oh SH, Lee BH.
    Biochem Pharmacol; 2003 Sep 01; 66(5):725-31. PubMed ID: 12948852
    [Abstract] [Full Text] [Related]

  • 14. Cell type specific involvement of death receptor and mitochondrial pathways in drug-induced apoptosis.
    Fulda S, Meyer E, Friesen C, Susin SA, Kroemer G, Debatin KM.
    Oncogene; 2001 Mar 01; 20(9):1063-75. PubMed ID: 11314043
    [Abstract] [Full Text] [Related]

  • 15. Novel mechanisms of apoptosis induced by histone deacetylase inhibitors.
    Peart MJ, Tainton KM, Ruefli AA, Dear AE, Sedelies KA, O'Reilly LA, Waterhouse NJ, Trapani JA, Johnstone RW.
    Cancer Res; 2003 Aug 01; 63(15):4460-71. PubMed ID: 12907619
    [Abstract] [Full Text] [Related]

  • 16. Reovirus-induced apoptosis requires both death receptor- and mitochondrial-mediated caspase-dependent pathways of cell death.
    Kominsky DJ, Bickel RJ, Tyler KL.
    Cell Death Differ; 2002 Sep 01; 9(9):926-33. PubMed ID: 12181743
    [Abstract] [Full Text] [Related]

  • 17. Induction of apoptosis in renal tubular cells by histone deacetylase inhibitors, a family of anticancer agents.
    Dong G, Wang L, Wang CY, Yang T, Kumar MV, Dong Z.
    J Pharmacol Exp Ther; 2008 Jun 01; 325(3):978-84. PubMed ID: 18310471
    [Abstract] [Full Text] [Related]

  • 18. SAHA induces apoptosis in hepatoma cells and synergistically interacts with the proteasome inhibitor Bortezomib.
    Emanuele S, Lauricella M, Carlisi D, Vassallo B, D'Anneo A, Di Fazio P, Vento R, Tesoriere G.
    Apoptosis; 2007 Jul 01; 12(7):1327-38. PubMed ID: 17351739
    [Abstract] [Full Text] [Related]

  • 19. The role of Apaf-1, caspase-9, and bid proteins in etoposide- or paclitaxel-induced mitochondrial events during apoptosis.
    Perkins CL, Fang G, Kim CN, Bhalla KN.
    Cancer Res; 2000 Mar 15; 60(6):1645-53. PubMed ID: 10749135
    [Abstract] [Full Text] [Related]

  • 20. Bim plays a crucial role in synergistic induction of apoptosis by the histone deacetylase inhibitor SBHA and TRAIL in melanoma cells.
    Gillespie S, Borrow J, Zhang XD, Hersey P.
    Apoptosis; 2006 Dec 15; 11(12):2251-65. PubMed ID: 17051334
    [Abstract] [Full Text] [Related]

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