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Journal Abstract Search

195 related items for PubMed ID: 11543678

  • 1. Acyclic and cyclopropyl analogues of adenosine bisphosphate antagonists of the P2Y1 receptor: structure-activity relationships and receptor docking.
    Kim HS, Barak D, Harden TK, Boyer JL, Jacobson KA.
    J Med Chem; 2001 Sep 13; 44(19):3092-108. PubMed ID: 11543678
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  • 2. Acyclic analogues of adenosine bisphosphates as P2Y receptor antagonists: phosphate substitution leads to multiple pathways of inhibition of platelet aggregation.
    Xu B, Stephens A, Kirschenheuter G, Greslin AF, Cheng X, Sennelo J, Cattaneo M, Zighetti ML, Chen A, Kim SA, Kim HS, Bischofberger N, Cook G, Jacobson KA.
    J Med Chem; 2002 Dec 19; 45(26):5694-709. PubMed ID: 12477353
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  • 7. 2-Substitution of adenine nucleotide analogues containing a bicyclo[3.1.0]hexane ring system locked in a northern conformation: enhanced potency as P2Y1 receptor antagonists.
    Kim HS, Ohno M, Xu B, Kim HO, Choi Y, Ji XD, Maddileti S, Marquez VE, Harden TK, Jacobson KA.
    J Med Chem; 2003 Nov 06; 46(23):4974-87. PubMed ID: 14584948
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  • 10. Quantitation of the P2Y(1) receptor with a high affinity radiolabeled antagonist.
    Waldo GL, Corbitt J, Boyer JL, Ravi G, Kim HS, Ji XD, Lacy J, Jacobson KA, Harden TK.
    Mol Pharmacol; 2002 Nov 06; 62(5):1249-57. PubMed ID: 12391289
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  • 11. Adenine nucleotide analogues locked in a Northern methanocarba conformation: enhanced stability and potency as P2Y(1) receptor agonists.
    Ravi RG, Kim HS, Servos J, Zimmermann H, Lee K, Maddileti S, Boyer JL, Harden TK, Jacobson KA.
    J Med Chem; 2002 May 09; 45(10):2090-100. PubMed ID: 11985476
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  • 13. Competitive and selective antagonism of P2Y1 receptors by N6-methyl 2'-deoxyadenosine 3',5'-bisphosphate.
    Boyer JL, Mohanram A, Camaioni E, Jacobson KA, Harden TK.
    Br J Pharmacol; 1998 May 09; 124(1):1-3. PubMed ID: 9630335
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  • 16. Structure-activity relationships of pyridoxal phosphate derivatives as potent and selective antagonists of P2X1 receptors.
    Kim YC, Brown SG, Harden TK, Boyer JL, Dubyak G, King BF, Burnstock G, Jacobson KA.
    J Med Chem; 2001 Feb 01; 44(3):340-9. PubMed ID: 11462975
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  • 17. 2-Chloro N(6)-methyl-(N)-methanocarba-2'-deoxyadenosine-3',5'-bisphosphate is a selective high affinity P2Y(1) receptor antagonist.
    Boyer JL, Adams M, Ravi RG, Jacobson KA, Harden TK.
    Br J Pharmacol; 2002 Apr 01; 135(8):2004-10. PubMed ID: 11959804
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  • 18. Molecular basis for ADP-induced platelet activation. II. The P2Y1 receptor mediates ADP-induced intracellular calcium mobilization and shape change in platelets.
    Jin J, Daniel JL, Kunapuli SP.
    J Biol Chem; 1998 Jan 23; 273(4):2030-4. PubMed ID: 9442040
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  • 19. A pyridoxine cyclic phosphate and its 6-azoaryl derivative selectively potentiate and antagonize activation of P2X1 receptors.
    Jacobson KA, Kim YC, Wildman SS, Mohanram A, Harden TK, Boyer JL, King BF, Burnstock G.
    J Med Chem; 1998 Jun 18; 41(13):2201-6. PubMed ID: 9632352
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  • 20. Identification of competitive antagonists of the P2Y1 receptor.
    Boyer JL, Romero-Avila T, Schachter JB, Harden TK.
    Mol Pharmacol; 1996 Nov 18; 50(5):1323-9. PubMed ID: 8913364
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