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212 related items for PubMed ID: 11551917

  • 1. Rac affects invasion of human renal cell carcinomas by up-regulating tissue inhibitor of metalloproteinases (TIMP)-1 and TIMP-2 expression.
    Engers R, Springer E, Michiels F, Collard JG, Gabbert HE.
    J Biol Chem; 2001 Nov 09; 276(45):41889-97. PubMed ID: 11551917
    [Abstract] [Full Text] [Related]

  • 2. Rac upregulates tissue inhibitor of metalloproteinase-1 expression by redox-dependent activation of extracellular signal-regulated kinase signaling.
    Engers R, Springer E, Kehren V, Simic T, Young DA, Beier J, Klotz LO, Clark IM, Sies H, Gabbert HE.
    FEBS J; 2006 Oct 09; 273(20):4754-69. PubMed ID: 16984397
    [Abstract] [Full Text] [Related]

  • 3. The guanine nucleotide exchange factor Tiam1 affects neuronal morphology; opposing roles for the small GTPases Rac and Rho.
    Leeuwen FN, Kain HE, Kammen RA, Michiels F, Kranenburg OW, Collard JG.
    J Cell Biol; 1997 Nov 03; 139(3):797-807. PubMed ID: 9348295
    [Abstract] [Full Text] [Related]

  • 4. A role for Rac in Tiam1-induced membrane ruffling and invasion.
    Michiels F, Habets GG, Stam JC, van der Kammen RA, Collard JG.
    Nature; 1995 May 25; 375(6529):338-40. PubMed ID: 7753201
    [Abstract] [Full Text] [Related]

  • 5. The guanine nucleotide exchange factor Tiam1: a Janus-faced molecule in cellular signaling.
    Boissier P, Huynh-Do U.
    Cell Signal; 2014 Mar 25; 26(3):483-91. PubMed ID: 24308970
    [Abstract] [Full Text] [Related]

  • 6. Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior.
    Sander EE, ten Klooster JP, van Delft S, van der Kammen RA, Collard JG.
    J Cell Biol; 1999 Nov 29; 147(5):1009-22. PubMed ID: 10579721
    [Abstract] [Full Text] [Related]

  • 7. HUWE1 ubiquitylates and degrades the RAC activator TIAM1 promoting cell-cell adhesion disassembly, migration, and invasion.
    Vaughan L, Tan CT, Chapman A, Nonaka D, Mack NA, Smith D, Booton R, Hurlstone AF, Malliri A.
    Cell Rep; 2015 Jan 06; 10(1):88-102. PubMed ID: 25543140
    [Abstract] [Full Text] [Related]

  • 8. Rac is a dominant regulator of cadherin-directed actin assembly that is activated by adhesive ligation independently of Tiam1.
    Kraemer A, Goodwin M, Verma S, Yap AS, Ali RG.
    Am J Physiol Cell Physiol; 2007 Mar 06; 292(3):C1061-9. PubMed ID: 17020937
    [Abstract] [Full Text] [Related]

  • 9. The role of the guanine nucleotide exchange factor Tiam1 in cellular migration, invasion, adhesion and tumor progression.
    Minard ME, Kim LS, Price JE, Gallick GE.
    Breast Cancer Res Treat; 2004 Mar 06; 84(1):21-32. PubMed ID: 14999151
    [Abstract] [Full Text] [Related]

  • 10. Tiam1 mutations in human renal-cell carcinomas.
    Engers R, Zwaka TP, Gohr L, Weber A, Gerharz CD, Gabbert HE.
    Int J Cancer; 2000 Nov 01; 88(3):369-76. PubMed ID: 11054665
    [Abstract] [Full Text] [Related]

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  • 12. The Rac exchange factor Tiam1 is required for the establishment and maintenance of cadherin-based adhesions.
    Malliri A, van Es S, Huveneers S, Collard JG.
    J Biol Chem; 2004 Jul 16; 279(29):30092-8. PubMed ID: 15138270
    [Abstract] [Full Text] [Related]

  • 13. Invasion of T-lymphoma cells: cooperation between Rho family GTPases and lysophospholipid receptor signaling.
    Stam JC, Michiels F, van der Kammen RA, Moolenaar WH, Collard JG.
    EMBO J; 1998 Jul 15; 17(14):4066-74. PubMed ID: 9670021
    [Abstract] [Full Text] [Related]

  • 14. Regulation of breast cancer cell motility by T-cell lymphoma invasion and metastasis-inducing protein.
    Adams HC, Chen R, Liu Z, Whitehead IP.
    Breast Cancer Res; 2010 Jul 15; 12(5):R69. PubMed ID: 20819206
    [Abstract] [Full Text] [Related]

  • 15. Interaction between Tiam1 and the Arp2/3 complex links activation of Rac to actin polymerization.
    Ten Klooster JP, Evers EE, Janssen L, Machesky LM, Michiels F, Hordijk P, Collard JG.
    Biochem J; 2006 Jul 01; 397(1):39-45. PubMed ID: 16599904
    [Abstract] [Full Text] [Related]

  • 16. Regulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activation.
    Michiels F, Stam JC, Hordijk PL, van der Kammen RA, Ruuls-Van Stalle L, Feltkamp CA, Collard JG.
    J Cell Biol; 1997 Apr 21; 137(2):387-98. PubMed ID: 9128250
    [Abstract] [Full Text] [Related]

  • 17. PTEN gene transfer suppresses the invasive potential of human malignant gliomas by regulating cell invasion-related molecules.
    Furukawa K, Kumon Y, Harada H, Kohno S, Nagato S, Teraoka M, Fujiwara S, Nakagawa K, Hamada K, Ohnishi T.
    Int J Oncol; 2006 Jul 21; 29(1):73-81. PubMed ID: 16773187
    [Abstract] [Full Text] [Related]

  • 18. Rac activation by lysophosphatidic acid LPA1 receptors through the guanine nucleotide exchange factor Tiam1.
    Van Leeuwen FN, Olivo C, Grivell S, Giepmans BN, Collard JG, Moolenaar WH.
    J Biol Chem; 2003 Jan 03; 278(1):400-6. PubMed ID: 12393875
    [Abstract] [Full Text] [Related]

  • 19. Ankyrin-Tiam1 interaction promotes Rac1 signaling and metastatic breast tumor cell invasion and migration.
    Bourguignon LY, Zhu H, Shao L, Chen YW.
    J Cell Biol; 2000 Jul 10; 150(1):177-91. PubMed ID: 10893266
    [Abstract] [Full Text] [Related]

  • 20. Relative expression of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in mouse renal cell carcinoma cells regulates their metastatic potential.
    Miyake H, Hara I, Gohji K, Yamanaka K, Hara S, Arakawa S, Nakajima M, Kamidono S.
    Clin Cancer Res; 1999 Oct 10; 5(10):2824-9. PubMed ID: 10537348
    [Abstract] [Full Text] [Related]

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