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604 related items for PubMed ID: 11553618

  • 1. Metal-triggered structural transformations, aggregation, and fibrillation of human alpha-synuclein. A possible molecular NK between Parkinson's disease and heavy metal exposure.
    Uversky VN, Li J, Fink AL.
    J Biol Chem; 2001 Nov 23; 276(47):44284-96. PubMed ID: 11553618
    [Abstract] [Full Text] [Related]

  • 2. Synergistic effects of pesticides and metals on the fibrillation of alpha-synuclein: implications for Parkinson's disease.
    Uversky VN, Li J, Bower K, Fink AL.
    Neurotoxicology; 2002 Oct 23; 23(4-5):527-36. PubMed ID: 12428725
    [Abstract] [Full Text] [Related]

  • 3. Biophysical properties of the synucleins and their propensities to fibrillate: inhibition of alpha-synuclein assembly by beta- and gamma-synucleins.
    Uversky VN, Li J, Souillac P, Millett IS, Doniach S, Jakes R, Goedert M, Fink AL.
    J Biol Chem; 2002 Apr 05; 277(14):11970-8. PubMed ID: 11812782
    [Abstract] [Full Text] [Related]

  • 4. Effect of familial Parkinson's disease point mutations A30P and A53T on the structural properties, aggregation, and fibrillation of human alpha-synuclein.
    Li J, Uversky VN, Fink AL.
    Biochemistry; 2001 Sep 25; 40(38):11604-13. PubMed ID: 11560511
    [Abstract] [Full Text] [Related]

  • 5. Pesticides directly accelerate the rate of alpha-synuclein fibril formation: a possible factor in Parkinson's disease.
    Uversky VN, Li J, Fink AL.
    FEBS Lett; 2001 Jul 06; 500(3):105-8. PubMed ID: 11445065
    [Abstract] [Full Text] [Related]

  • 6. Evidence for a partially folded intermediate in alpha-synuclein fibril formation.
    Uversky VN, Li J, Fink AL.
    J Biol Chem; 2001 Apr 06; 276(14):10737-44. PubMed ID: 11152691
    [Abstract] [Full Text] [Related]

  • 7. Forcing nonamyloidogenic beta-synuclein to fibrillate.
    Yamin G, Munishkina LA, Karymov MA, Lyubchenko YL, Uversky VN, Fink AL.
    Biochemistry; 2005 Jun 28; 44(25):9096-107. PubMed ID: 15966733
    [Abstract] [Full Text] [Related]

  • 8. Role of protein-water interactions and electrostatics in alpha-synuclein fibril formation.
    Munishkina LA, Henriques J, Uversky VN, Fink AL.
    Biochemistry; 2004 Mar 23; 43(11):3289-300. PubMed ID: 15023080
    [Abstract] [Full Text] [Related]

  • 9. Heparin and other glycosaminoglycans stimulate the formation of amyloid fibrils from alpha-synuclein in vitro.
    Cohlberg JA, Li J, Uversky VN, Fink AL.
    Biochemistry; 2002 Feb 05; 41(5):1502-11. PubMed ID: 11814343
    [Abstract] [Full Text] [Related]

  • 10. Stabilization of partially folded conformation during alpha-synuclein oligomerization in both purified and cytosolic preparations.
    Uversky VN, Lee HJ, Li J, Fink AL, Lee SJ.
    J Biol Chem; 2001 Nov 23; 276(47):43495-8. PubMed ID: 11590163
    [Abstract] [Full Text] [Related]

  • 11. Metal-catalyzed oxidation of alpha-synuclein: helping to define the relationship between oligomers, protofibrils, and filaments.
    Cole NB, Murphy DD, Lebowitz J, Di Noto L, Levine RL, Nussbaum RL.
    J Biol Chem; 2005 Mar 11; 280(10):9678-90. PubMed ID: 15615715
    [Abstract] [Full Text] [Related]

  • 12. Conformational behavior of human alpha-synuclein is modulated by familial Parkinson's disease point mutations A30P and A53T.
    Li J, Uversky VN, Fink AL.
    Neurotoxicology; 2002 Oct 11; 23(4-5):553-67. PubMed ID: 12428728
    [Abstract] [Full Text] [Related]

  • 13. Certain metals trigger fibrillation of methionine-oxidized alpha-synuclein.
    Yamin G, Glaser CB, Uversky VN, Fink AL.
    J Biol Chem; 2003 Jul 25; 278(30):27630-5. PubMed ID: 12754258
    [Abstract] [Full Text] [Related]

  • 14. Effect of metals on herbicides-alpha-synuclein association: a possible factor in neurodegenerative disease studied by capillary electrophoresis.
    André C, Truong TT, Robert JF, Guillaume YC.
    Electrophoresis; 2005 Sep 25; 26(17):3256-64. PubMed ID: 16143978
    [Abstract] [Full Text] [Related]

  • 15. Conformational behavior and aggregation of alpha-synuclein in organic solvents: modeling the effects of membranes.
    Munishkina LA, Phelan C, Uversky VN, Fink AL.
    Biochemistry; 2003 Mar 11; 42(9):2720-30. PubMed ID: 12614167
    [Abstract] [Full Text] [Related]

  • 16. The flavonoid baicalein inhibits fibrillation of alpha-synuclein and disaggregates existing fibrils.
    Zhu M, Rajamani S, Kaylor J, Han S, Zhou F, Fink AL.
    J Biol Chem; 2004 Jun 25; 279(26):26846-57. PubMed ID: 15096521
    [Abstract] [Full Text] [Related]

  • 17. Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease.
    Conway KA, Harper JD, Lansbury PT.
    Nat Med; 1998 Nov 25; 4(11):1318-20. PubMed ID: 9809558
    [Abstract] [Full Text] [Related]

  • 18. Magnesium inhibits spontaneous and iron-induced aggregation of alpha-synuclein.
    Golts N, Snyder H, Frasier M, Theisler C, Choi P, Wolozin B.
    J Biol Chem; 2002 May 03; 277(18):16116-23. PubMed ID: 11850416
    [Abstract] [Full Text] [Related]

  • 19. Methionine oxidation, alpha-synuclein and Parkinson's disease.
    Glaser CB, Yamin G, Uversky VN, Fink AL.
    Biochim Biophys Acta; 2005 Jan 17; 1703(2):157-69. PubMed ID: 15680224
    [Abstract] [Full Text] [Related]

  • 20. The association of alpha-synuclein with membranes affects bilayer structure, stability, and fibril formation.
    Zhu M, Li J, Fink AL.
    J Biol Chem; 2003 Oct 10; 278(41):40186-97. PubMed ID: 12885775
    [Abstract] [Full Text] [Related]


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