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861 related items for PubMed ID: 11553704

  • 1. Deoxycholic acid (DCA) causes ligand-independent activation of epidermal growth factor receptor (EGFR) and FAS receptor in primary hepatocytes: inhibition of EGFR/mitogen-activated protein kinase-signaling module enhances DCA-induced apoptosis.
    Qiao L, Studer E, Leach K, McKinstry R, Gupta S, Decker R, Kukreja R, Valerie K, Nagarkatti P, El Deiry W, Molkentin J, Schmidt-Ullrich R, Fisher PB, Grant S, Hylemon PB, Dent P.
    Mol Biol Cell; 2001 Sep; 12(9):2629-45. PubMed ID: 11553704
    [Abstract] [Full Text] [Related]

  • 2. Inhibition of the MAPK and PI3K pathways enhances UDCA-induced apoptosis in primary rodent hepatocytes.
    Qiao L, Yacoub A, Studer E, Gupta S, Pei XY, Grant S, Hylemon PB, Dent P.
    Hepatology; 2002 Apr; 35(4):779-89. PubMed ID: 11915023
    [Abstract] [Full Text] [Related]

  • 3. Cyclin kinase inhibitor p21 potentiates bile acid-induced apoptosis in hepatocytes that is dependent on p53.
    Qiao L, McKinstry R, Gupta S, Gilfor D, Windle JJ, Hylemon PB, Grant S, Fisher PB, Dent P.
    Hepatology; 2002 Jul; 36(1):39-48. PubMed ID: 12085347
    [Abstract] [Full Text] [Related]

  • 4. Mitogen-activated protein kinase/extracellular signal-regulated kinase signaling in activated T cells abrogates TRAIL-induced apoptosis upstream of the mitochondrial amplification loop and caspase-8.
    Söderström TS, Poukkula M, Holmström TH, Heiskanen KM, Eriksson JE.
    J Immunol; 2002 Sep 15; 169(6):2851-60. PubMed ID: 12218097
    [Abstract] [Full Text] [Related]

  • 5. Bile acid regulation of C/EBPbeta, CREB, and c-Jun function, via the extracellular signal-regulated kinase and c-Jun NH2-terminal kinase pathways, modulates the apoptotic response of hepatocytes.
    Qiao L, Han SI, Fang Y, Park JS, Gupta S, Gilfor D, Amorino G, Valerie K, Sealy L, Engelhardt JF, Grant S, Hylemon PB, Dent P.
    Mol Cell Biol; 2003 May 15; 23(9):3052-66. PubMed ID: 12697808
    [Abstract] [Full Text] [Related]

  • 6. Deoxycholic acid activates the c-Jun N-terminal kinase pathway via FAS receptor activation in primary hepatocytes. Role of acidic sphingomyelinase-mediated ceramide generation in FAS receptor activation.
    Gupta S, Natarajan R, Payne SG, Studer EJ, Spiegel S, Dent P, Hylemon PB.
    J Biol Chem; 2004 Feb 13; 279(7):5821-8. PubMed ID: 14660582
    [Abstract] [Full Text] [Related]

  • 7. 17-Allylamino-17-demethoxygeldanamycin enhances the lethality of deoxycholic acid in primary rodent hepatocytes and established cell lines.
    Mitchell C, Park MA, Zhang G, Han SI, Harada H, Franklin RA, Yacoub A, Li PL, Hylemon PB, Grant S, Dent P.
    Mol Cancer Ther; 2007 Feb 13; 6(2):618-32. PubMed ID: 17308059
    [Abstract] [Full Text] [Related]

  • 8. Multiple cyclin kinase inhibitors promote bile acid-induced apoptosis and autophagy in primary hepatocytes via p53-CD95-dependent signaling.
    Zhang G, Park MA, Mitchell C, Walker T, Hamed H, Studer E, Graf M, Rahmani M, Gupta S, Hylemon PB, Fisher PB, Grant S, Dent P.
    J Biol Chem; 2008 Sep 05; 283(36):24343-58. PubMed ID: 18614532
    [Abstract] [Full Text] [Related]

  • 9. The bile acid-activated phosphatidylinositol 3-kinase pathway inhibits Fas apoptosis upstream of bid in rodent hepatocytes.
    Takikawa Y, Miyoshi H, Rust C, Roberts P, Siegel R, Mandal PK, Millikan RE, Gores GJ.
    Gastroenterology; 2001 Jun 05; 120(7):1810-7. PubMed ID: 11375961
    [Abstract] [Full Text] [Related]

  • 10. Bile acids induce mitochondrial ROS, which promote activation of receptor tyrosine kinases and signaling pathways in rat hepatocytes.
    Fang Y, Han SI, Mitchell C, Gupta S, Studer E, Grant S, Hylemon PB, Dent P.
    Hepatology; 2004 Oct 05; 40(4):961-71. PubMed ID: 15382121
    [Abstract] [Full Text] [Related]

  • 11. Activation of the Raf-1/MEK/ERK cascade by bile acids occurs via the epidermal growth factor receptor in primary rat hepatocytes.
    Rao YP, Studer EJ, Stravitz RT, Gupta S, Qiao L, Dent P, Hylemon PB.
    Hepatology; 2002 Feb 05; 35(2):307-14. PubMed ID: 11826403
    [Abstract] [Full Text] [Related]

  • 12. A role for caspase-8 and c-FLIPL in proliferation and cell-cycle progression of primary hepatocytes.
    Gilot D, Serandour AL, Ilyin GP, Lagadic-Gossmann D, Loyer P, Corlu A, Coutant A, Baffet G, Peter ME, Fardel O, Guguen-Guillouzo C.
    Carcinogenesis; 2005 Dec 05; 26(12):2086-94. PubMed ID: 16033771
    [Abstract] [Full Text] [Related]

  • 13. Bile Acid Toxicity and Protein Kinases.
    Engin A.
    Adv Exp Med Biol; 2021 Dec 05; 1275():229-258. PubMed ID: 33539018
    [Abstract] [Full Text] [Related]

  • 14. Role of p38 mitogen-activated protein kinase phosphorylation and Fas-Fas ligand interaction in morphine-induced macrophage apoptosis.
    Singhal PC, Bhaskaran M, Patel J, Patel K, Kasinath BS, Duraisamy S, Franki N, Reddy K, Kapasi AA.
    J Immunol; 2002 Apr 15; 168(8):4025-33. PubMed ID: 11937560
    [Abstract] [Full Text] [Related]

  • 15. Protection against Fas receptor-mediated apoptosis in hepatocytes and nonparenchymal cells by a caspase-8 inhibitor in vivo: evidence for a postmitochondrial processing of caspase-8.
    Bajt ML, Lawson JA, Vonderfecht SL, Gujral JS, Jaeschke H.
    Toxicol Sci; 2000 Nov 15; 58(1):109-17. PubMed ID: 11053547
    [Abstract] [Full Text] [Related]

  • 16. Differential requirement for c-Jun NH2-terminal kinase in TNFalpha- and Fas-mediated apoptosis in hepatocytes.
    Schwabe RF, Uchinami H, Qian T, Bennett BL, Lemasters JJ, Brenner DA.
    FASEB J; 2004 Apr 15; 18(6):720-2. PubMed ID: 14766793
    [Abstract] [Full Text] [Related]

  • 17. Dominant negative EGFR-CD533 and inhibition of MAPK modify JNK1 activation and enhance radiation toxicity of human mammary carcinoma cells.
    Reardon DB, Contessa JN, Mikkelsen RB, Valerie K, Amir C, Dent P, Schmidt-Ullrich RK.
    Oncogene; 1999 Aug 19; 18(33):4756-66. PubMed ID: 10467423
    [Abstract] [Full Text] [Related]

  • 18. Activation and role of mitogen-activated protein kinases in deoxycholic acid-induced apoptosis.
    Qiao D, Stratagouleas ED, Martinez JD.
    Carcinogenesis; 2001 Jan 19; 22(1):35-41. PubMed ID: 11159738
    [Abstract] [Full Text] [Related]

  • 19. Apicidin, a histone deacetylase inhibitor, induces apoptosis and Fas/Fas ligand expression in human acute promyelocytic leukemia cells.
    Kwon SH, Ahn SH, Kim YK, Bae GU, Yoon JW, Hong S, Lee HY, Lee YW, Lee HW, Han JW.
    J Biol Chem; 2002 Jan 18; 277(3):2073-80. PubMed ID: 11698395
    [Abstract] [Full Text] [Related]

  • 20. Defining characteristics of Types I and II apoptotic cells in response to TRAIL.
    Ozören N, El-Deiry WS.
    Neoplasia; 2002 Jan 18; 4(6):551-7. PubMed ID: 12407450
    [Abstract] [Full Text] [Related]

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