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Journal Abstract Search

264 related items for PubMed ID: 11562438

  • 1. Changes of cooperativity between N-methylscopolamine and allosteric modulators alcuronium and gallamine induced by mutations of external loops of muscarinic M(3) receptors.
    Krejcí A, Tucek S.
    Mol Pharmacol; 2001 Oct; 60(4):761-7. PubMed ID: 11562438
    [Abstract] [Full Text] [Related]

  • 2. Competition between positive and negative allosteric effectors on muscarinic receptors.
    Proska J, Tucek S.
    Mol Pharmacol; 1995 Oct; 48(4):696-702. PubMed ID: 7476896
    [Abstract] [Full Text] [Related]

  • 3. Subtype selectivity of the positive allosteric action of alcuronium at cloned M1-M5 muscarinic acetylcholine receptors.
    Jakubík J, Bacáková L, el-Fakahany EE, Tucek S.
    J Pharmacol Exp Ther; 1995 Sep; 274(3):1077-83. PubMed ID: 7562472
    [Abstract] [Full Text] [Related]

  • 4. Asparagine, valine, and threonine in the third extracellular loop of muscarinic receptor have essential roles in the positive cooperativity of strychnine-like allosteric modulators.
    Jakubík J, Krejcí A, Dolezal V.
    J Pharmacol Exp Ther; 2005 May; 313(2):688-96. PubMed ID: 15647330
    [Abstract] [Full Text] [Related]

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  • 6. Testing the specificity of allosteric modulators of muscarinic receptors in phylogenetically closely related histamine H1-receptors.
    Franken C, Tränkle C, Mohr K.
    Naunyn Schmiedebergs Arch Pharmacol; 2000 Feb; 361(2):107-12. PubMed ID: 10685864
    [Abstract] [Full Text] [Related]

  • 7. Regulation of M2 muscarinic acetylcholine receptor expression and signaling by prolonged exposure to allosteric modulators.
    May LT, Lin Y, Sexton PM, Christopoulos A.
    J Pharmacol Exp Ther; 2005 Jan; 312(1):382-90. PubMed ID: 15333678
    [Abstract] [Full Text] [Related]

  • 8. Probing of the location of the allosteric site on m1 muscarinic receptors by site-directed mutagenesis.
    Matsui H, Lazareno S, Birdsall NJ.
    Mol Pharmacol; 1995 Jan; 47(1):88-98. PubMed ID: 7838137
    [Abstract] [Full Text] [Related]

  • 9. Positive cooperativity in the binding of alcuronium and N-methylscopolamine to muscarinic acetylcholine receptors.
    Tucek S, Musílková J, Nedoma J, Proska J, Shelkovnikov S, Vorlícek J.
    Mol Pharmacol; 1990 Nov; 38(5):674-80. PubMed ID: 2233700
    [Abstract] [Full Text] [Related]

  • 10. Three allosteric modulators act at a common site, distinct from that of competitive antagonists, at muscarinic acetylcholine M2 receptors.
    Lanzafame A, Christopoulos A, Mitchelson F.
    J Pharmacol Exp Ther; 1997 Jul; 282(1):278-85. PubMed ID: 9223565
    [Abstract] [Full Text] [Related]

  • 11. Application of a kinetic model to the apparently complex behavior of negative and positive allosteric modulators of muscarinic acetylcholine receptors.
    Avlani V, May LT, Sexton PM, Christopoulos A.
    J Pharmacol Exp Ther; 2004 Mar; 308(3):1062-72. PubMed ID: 14711931
    [Abstract] [Full Text] [Related]

  • 12. An unusual form of the association binding kinetics of N-[3H]methylscopolamine to the split muscarinic M2trunk/M2tail receptor.
    Novi F, Scarselli M, Corsini GU, Maggio R.
    J Pharmacol Exp Ther; 2003 May; 305(2):786-95. PubMed ID: 12606698
    [Abstract] [Full Text] [Related]

  • 13. Interactions of alcuronium, TMB-8, and other allosteric ligands with muscarinic acetylcholine receptors: studies with chimeric receptors.
    Ellis J, Seidenberg M.
    Mol Pharmacol; 2000 Dec; 58(6):1451-60. PubMed ID: 11093785
    [Abstract] [Full Text] [Related]

  • 14. Modes of allosteric interactions with free and [3H]N-methylscopolamine-occupied muscarinic M2 receptors as deduced from buffer-dependent potency shifts.
    Schröter A, Tränkle C, Mohr K.
    Naunyn Schmiedebergs Arch Pharmacol; 2000 Dec; 362(6):512-9. PubMed ID: 11138843
    [Abstract] [Full Text] [Related]

  • 15. Using a radioalloster to test predictions of the cooperativity model for gallamine binding to the allosteric site of muscarinic acetylcholine M(2) receptors.
    Tränkle C, Weyand O, Schröter A, Mohr K.
    Mol Pharmacol; 1999 Nov; 56(5):962-5. PubMed ID: 10531401
    [Abstract] [Full Text] [Related]

  • 16. Muscarinic allosteric modulation: M2/M3 subtype selectivity of gallamine is independent of G-protein coupling specificity.
    Tränkle C, Kostenis E, Mohr K.
    Naunyn Schmiedebergs Arch Pharmacol; 2001 Aug; 364(2):172-8. PubMed ID: 11534857
    [Abstract] [Full Text] [Related]

  • 17. Mechanisms of steric and cooperative actions of alcuronium on cardiac muscarinic acetylcholine receptors.
    Proska J, Tucek S.
    Mol Pharmacol; 1994 Apr; 45(4):709-17. PubMed ID: 8183250
    [Abstract] [Full Text] [Related]

  • 18. Interactions of orthosteric and allosteric ligands with [3H]dimethyl-W84 at the common allosteric site of muscarinic M2 receptors.
    Tränkle C, Weyand O, Voigtländer U, Mynett A, Lazareno S, Birdsall NJ, Mohr K.
    Mol Pharmacol; 2003 Jul; 64(1):180-90. PubMed ID: 12815174
    [Abstract] [Full Text] [Related]

  • 19. The impact of orthosteric radioligand depletion on the quantification of allosteric modulator interactions.
    Avlani VA, McLoughlin DJ, Sexton PM, Christopoulos A.
    J Pharmacol Exp Ther; 2008 Jun; 325(3):927-34. PubMed ID: 18322151
    [Abstract] [Full Text] [Related]

  • 20. Search for lead structures to develop new allosteric modulators of muscarinic receptors.
    Tränkle C, Kostenis E, Burgmer U, Mohr K.
    J Pharmacol Exp Ther; 1996 Nov; 279(2):926-33. PubMed ID: 8930201
    [Abstract] [Full Text] [Related]

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