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Journal Abstract Search

181 related items for PubMed ID: 11563930

  • 21. Indolequinone antitumor agents: reductive activation and elimination from (5-methoxy-1-methyl-4,7-dioxoindol-3-yl)methyl derivatives and hypoxia-selective cytotoxicity in vitro.
    Naylor MA, Swann E, Everett SA, Jaffar M, Nolan J, Robertson N, Lockyer SD, Patel KB, Dennis MF, Stratford MR, Wardman P, Adams GE, Moody CJ, Stratford IJ.
    J Med Chem; 1998 Jul 16; 41(15):2720-31. PubMed ID: 9667963
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  • 22. Aziridinyl quinone antitumor agents based on indoles and cyclopent[b]indoles: structure-activity relationships for cytotoxicity and antitumor activity.
    Skibo EB, Xing C, Dorr RT.
    J Med Chem; 2001 Oct 25; 44(22):3545-62. PubMed ID: 11606119
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  • 23. Design, synthesis, and biological evaluation of NAD(P)H: Quinone oxidoreductase (NQO1)-targeted oridonin prodrugs possessing indolequinone moiety for hypoxia-selective activation.
    Xu S, Yao H, Pei L, Hu M, Li D, Qiu Y, Wang G, Wu L, Yao H, Zhu Z, Xu J.
    Eur J Med Chem; 2017 May 26; 132():310-321. PubMed ID: 28395199
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  • 25. COMPARE analysis of the toxicity of an iminoquinone derivative of the imidazo[5,4-f]benzimidazoles with NAD(P)H:quinone oxidoreductase 1 (NQO1) activity and computational docking of quinones as NQO1 substrates.
    Fagan V, Bonham S, Carty MP, Saenz-Méndez P, Eriksson LA, Aldabbagh F.
    Bioorg Med Chem; 2012 May 15; 20(10):3223-32. PubMed ID: 22522008
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  • 26. Lavendamycin antitumor agents: structure-based design, synthesis, and NAD(P)H:quinone oxidoreductase 1 (NQO1) model validation with molecular docking and biological studies.
    Hassani M, Cai W, Koelsch KH, Holley DC, Rose AS, Olang F, Lineswala JP, Holloway WG, Gerdes JM, Behforouz M, Beall HD.
    J Med Chem; 2008 Jun 12; 51(11):3104-15. PubMed ID: 18457384
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  • 27. Synthesis and biological evaluation of novel isothiazoloquinoline quinone analogues.
    Chen L, Xie YZ, Luo ZY, Liu LJ, Zou ZZ, Liu HD, Kong FR, Hao Y, Gao JL, Wang LL, Ma DY, Liu SY.
    Bioorg Med Chem Lett; 2020 Aug 15; 30(16):127286. PubMed ID: 32631508
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  • 29. Novel β-carboline-based indole-4,7-quinone derivatives as NAD(P)H: Quinone-oxidoreductase-1 inhibitor with potent antitumor activities by inducing reactive oxygen species, apoptosis, and DNA damage.
    Guo Y, Xu L, Ling C, Yang T, Zheng W, Lv J, Guo Q, Chen B.
    Chem Biol Drug Des; 2020 Dec 15; 96(6):1433-1446. PubMed ID: 32592323
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  • 30. Expression of human NAD(P)H: quinone oxidoreductase (DT-diaphorase) in Chinese hamster ovary cells: effect on the toxicity of antitumor quinones.
    Gustafson DL, Beall HD, Bolton EM, Ross D, Waldren CA.
    Mol Pharmacol; 1996 Oct 15; 50(4):728-35. PubMed ID: 8863816
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  • 34. Synthesis, metabolism and in vitro cytotoxicity studies on novel lavendamycin antitumor agents.
    Cai W, Hassani M, Karki R, Walter ED, Koelsch KH, Seradj H, Lineswala JP, Mirzaei H, York JS, Olang F, Sedighi M, Lucas JS, Eads TJ, Rose AS, Charkhzarrin S, Hermann NG, Beall HD, Behforouz M.
    Bioorg Med Chem; 2010 Mar 01; 18(5):1899-909. PubMed ID: 20149966
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  • 35. NAD(P)H:quinone oxidoreductase-1-dependent and -independent cytotoxicity of potent quinone Cdc25 phosphatase inhibitors.
    Han Y, Shen H, Carr BI, Wipf P, Lazo JS, Pan SS.
    J Pharmacol Exp Ther; 2004 Apr 01; 309(1):64-70. PubMed ID: 14718602
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  • 39. Synthesis of pyridino[2,3-f]indole-4,9-dione and 6,7-disubstituted quinoline-5,8-dione derivatives and evaluation on their cytotoxic activity.
    Suh ME, Park SY, Lee CO.
    Bioorg Med Chem; 2001 Nov 01; 9(11):2979-86. PubMed ID: 11597479
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  • 40. Studies on quinones. Part 46. Synthesis and in vitro antitumor evaluation of aminopyrimidoisoquinolinequinones.
    Vásquez D, Rodríguez JA, Theoduloz C, Calderon PB, Valderrama JA.
    Eur J Med Chem; 2010 Nov 01; 45(11):5234-42. PubMed ID: 20828890
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