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888 related items for PubMed ID: 11566026

  • 21. Identification of a meander region proline residue critical for heme binding to cytochrome P450: implications for the catalytic function of human CYP4B1.
    Zheng YM, Fisher MB, Yokotani N, Fujii-Kuriyama Y, Rettie AE.
    Biochemistry; 1998 Sep 15; 37(37):12847-51. PubMed ID: 9737862
    [Abstract] [Full Text] [Related]

  • 22. Substrate-assisted movement of the catalytic Lys 215 during domain closure: site-directed mutagenesis studies of human 3-phosphoglycerate kinase.
    Flachner B, Varga A, Szabó J, Barna L, Hajdú I, Gyimesi G, Závodszky P, Vas M.
    Biochemistry; 2005 Dec 27; 44(51):16853-65. PubMed ID: 16363799
    [Abstract] [Full Text] [Related]

  • 23. The role of the conserved threonine in P450 BM3 oxygen activation: substrate-determined hydroxylation activity of the Thr268Ala mutant.
    Cryle MJ, De Voss JJ.
    Chembiochem; 2008 Jan 25; 9(2):261-6. PubMed ID: 18161730
    [Abstract] [Full Text] [Related]

  • 24. Site-directed mutagenesis of the conserved threonine (Thr243) of the distal helix of fungal cytochrome P450nor.
    Okamoto N, Imai Y, Shoun H, Shiro Y.
    Biochemistry; 1998 Jun 23; 37(25):8839-47. PubMed ID: 9636024
    [Abstract] [Full Text] [Related]

  • 25. Site-directed mutagenesis of active site residues of phosphite dehydrogenase.
    Woodyer R, Wheatley JL, Relyea HA, Rimkus S, van der Donk WA.
    Biochemistry; 2005 Mar 29; 44(12):4765-74. PubMed ID: 15779903
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  • 26. Dual roles of Lys(57) at the dimer interface of human mitochondrial NAD(P)+-dependent malic enzyme.
    Hsieh JY, Liu JH, Fang YW, Hung HC.
    Biochem J; 2009 May 13; 420(2):201-9. PubMed ID: 19236308
    [Abstract] [Full Text] [Related]

  • 27. A conserved proline-rich sequence between the N-terminal signal-anchor and catalytic domains is required for assembly of functional cytochrome P450 2C2.
    Chen CD, Doray B, Kemper B.
    Arch Biochem Biophys; 1998 Feb 15; 350(2):233-8. PubMed ID: 9473296
    [Abstract] [Full Text] [Related]

  • 28. Analysis of four residues within substrate recognition site 4 of human cytochrome P450 3A4: role in steroid hydroxylase activity and alpha-naphthoflavone stimulation.
    Domanski TL, Liu J, Harlow GR, Halpert JR.
    Arch Biochem Biophys; 1998 Feb 15; 350(2):223-32. PubMed ID: 9473295
    [Abstract] [Full Text] [Related]

  • 29. Kinetic and structural effects of mutations of the catalytic amino-terminal proline in 4-oxalocrotonate tautomerase.
    Czerwinski RM, Johnson WH, Whitman CP.
    Biochemistry; 1997 Nov 25; 36(47):14551-60. PubMed ID: 9398173
    [Abstract] [Full Text] [Related]

  • 30. Arginines 97 and 108 in CYP2C9 are important determinants of the catalytic function.
    Ridderström M, Masimirembwa C, Trump-Kallmeyer S, Ahlefelt M, Otter C, Andersson TB.
    Biochem Biophys Res Commun; 2000 Apr 21; 270(3):983-7. PubMed ID: 10772937
    [Abstract] [Full Text] [Related]

  • 31. Versatile peroxidase oxidation of high redox potential aromatic compounds: site-directed mutagenesis, spectroscopic and crystallographic investigation of three long-range electron transfer pathways.
    Pérez-Boada M, Ruiz-Dueñas FJ, Pogni R, Basosi R, Choinowski T, Martínez MJ, Piontek K, Martínez AT.
    J Mol Biol; 2005 Nov 25; 354(2):385-402. PubMed ID: 16246366
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  • 32. Crystal structure of a catalytic-site mutant alpha-amylase from Bacillus subtilis complexed with maltopentaose.
    Fujimoto Z, Takase K, Doui N, Momma M, Matsumoto T, Mizuno H.
    J Mol Biol; 1998 Mar 27; 277(2):393-407. PubMed ID: 9514750
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  • 33. Characterization of a mutant Bacillus subtilis adenylosuccinate lyase equivalent to a mutant enzyme found in human adenylosuccinate lyase deficiency: asparagine 276 plays an important structural role.
    Palenchar JB, Colman RF.
    Biochemistry; 2003 Feb 25; 42(7):1831-41. PubMed ID: 12590570
    [Abstract] [Full Text] [Related]

  • 34. Implication by site-directed mutagenesis of Arg314 and Tyr316 in the coenzyme site of pig mitochondrial NADP-dependent isocitrate dehydrogenase.
    Lee P, Colman RF.
    Arch Biochem Biophys; 2002 May 01; 401(1):81-90. PubMed ID: 12054490
    [Abstract] [Full Text] [Related]

  • 35. Application of 3-dimensional homology modeling of cytochrome P450 2B1 for interpretation of site-directed mutagenesis results.
    Szklarz GD, Ornstein RL, Halpert JR.
    J Biomol Struct Dyn; 1994 Aug 01; 12(1):061-78. PubMed ID: 7848559
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  • 36. An aspartate residue at the extracellular boundary of TMII and an arginine residue in TMVII of the gastrin-releasing peptide receptor interact to facilitate heterotrimeric G protein coupling.
    Donohue PJ, Sainz E, Akeson M, Kroog GS, Mantey SA, Battey JF, Jensen RT, Northup JK.
    Biochemistry; 1999 Jul 20; 38(29):9366-72. PubMed ID: 10413511
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  • 37. Modification of the heme active site to increase the peroxidase activity of thermophilic cytochrome P450: a rational approach.
    Behera RK, Goyal S, Mazumdar S.
    J Inorg Biochem; 2010 Nov 20; 104(11):1185-94. PubMed ID: 20709408
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  • 38. Characterization of point mutations in patients with pyruvate dehydrogenase deficiency: role of methionine-181, proline-188, and arginine-349 in the alpha subunit.
    Tripatara A, Korotchkina LG, Patel MS.
    Arch Biochem Biophys; 1999 Jul 01; 367(1):39-50. PubMed ID: 10375397
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  • 39. Distal site aspartate is essential in the catalase activity of catalase-peroxidases.
    Jakopitsch C, Auer M, Regelsberger G, Jantschko W, Furtmüller PG, Rüker F, Obinger C.
    Biochemistry; 2003 May 13; 42(18):5292-300. PubMed ID: 12731870
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  • 40. Role of arginine 439 in substrate binding of 5-aminolevulinate synthase.
    Tan D, Harrison T, Hunter GA, Ferreira GC.
    Biochemistry; 1998 Feb 10; 37(6):1478-84. PubMed ID: 9484217
    [Abstract] [Full Text] [Related]


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