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734 related items for PubMed ID: 11586498

  • 1. Macrophage 3-hydroxy-3-methylglutaryl coenzyme a reductase activity in sitosterolemia: effects of increased cellular cholesterol and sitosterol concentrations.
    Nguyen LB, Salen G, Shefer S, Tint GS, Ruiz F.
    Metabolism; 2001 Oct; 50(10):1224-9. PubMed ID: 11586498
    [Abstract] [Full Text] [Related]

  • 2. 3-Hydroxy-3-methylglutaryl-coenzyme A reductase activity is inhibited by cholesterol and up-regulated by sitosterol in sitosterolemic fibroblasts.
    Honda A, Salen G, Honda M, Batta AK, Tint GS, Xu G, Chen TS, Tanaka N, Shefer S.
    J Lab Clin Med; 2000 Feb; 135(2):174-9. PubMed ID: 10695663
    [Abstract] [Full Text] [Related]

  • 3. Deficient ileal 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in sitosterolemia: sitosterol is not a feedback inhibitor of intestinal cholesterol biosynthesis.
    Nguyen LB, Salen G, Shefer S, Bullock J, Chen T, Tint GS, Chowdhary IR, Lerner S.
    Metabolism; 1994 Jul; 43(7):855-9. PubMed ID: 8028508
    [Abstract] [Full Text] [Related]

  • 4. Sitosterol reduces messenger RNA and protein expression levels of Niemann-Pick C1-like 1 in FHs 74 Int cells.
    Jesch ED, Seo JM, Carr TP, Lee JY.
    Nutr Res; 2009 Dec; 29(12):859-66. PubMed ID: 19963159
    [Abstract] [Full Text] [Related]

  • 5. The effect of increased hepatic sitosterol on the regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and cholesterol 7 alpha-hydroxylase in the rat and sitosterolemic homozygotes.
    Shefer S, Salen G, Bullock J, Nguyen LB, Ness GC, Vhao Z, Belamarich PF, Chowdhary I, Lerner S, Batta AK.
    Hepatology; 1994 Jul; 20(1 Pt 1):213-9. PubMed ID: 8020891
    [Abstract] [Full Text] [Related]

  • 6. Control of 3-hydroxy-3-methylglutaryl-CoA reductase activity in cultured human fibroblasts by very low density lipoproteins of subjects with hypertriglyceridemia.
    Gianturco SH, Gotto AM, Jackson RL, Patsch JR, Sybers HD, Taunton OD, Yeshurun DL, Smith LC.
    J Clin Invest; 1978 Feb; 61(2):320-8. PubMed ID: 202612
    [Abstract] [Full Text] [Related]

  • 7. Effects of 15-oxa-32-vinyl-lanost-8-ene-3 beta,32 diol on the expression of 3-hydroxy-3-methylglutaryl coenzyme A reductase and low density lipoprotein receptor in rat liver.
    Ness GC, Lopez D, Chambers CM, Zhao Z, Beach DL, Ko SS, Trzaskos JM.
    Arch Biochem Biophys; 1998 Sep 15; 357(2):259-64. PubMed ID: 9735166
    [Abstract] [Full Text] [Related]

  • 8. Decreased cholesterol biosynthesis in sitosterolemia with xanthomatosis: diminished mononuclear leukocyte 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and enzyme protein associated with increased low-density lipoprotein receptor function.
    Nguyen LB, Salen G, Shefer S, Tint GS, Shore V, Ness GC.
    Metabolism; 1990 Apr 15; 39(4):436-43. PubMed ID: 2325562
    [Abstract] [Full Text] [Related]

  • 9. Regulation of early cholesterol biosynthesis in rat liver: effects of sterols, bile acids, lovastatin, and BM 15.766 on 3-hydroxy-3-methylglutaryl coenzyme A synthase and acetoacetyl coenzyme A thiolase activities.
    Honda A, Salen G, Nguyen LB, Xu G, Tint GS, Batta AK, Shefer S.
    Hepatology; 1998 Jan 15; 27(1):154-9. PubMed ID: 9425931
    [Abstract] [Full Text] [Related]

  • 10. Post-transcriptional regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase by mevalonate.
    Straka MS, Panini SR.
    Arch Biochem Biophys; 1995 Feb 20; 317(1):235-43. PubMed ID: 7872789
    [Abstract] [Full Text] [Related]

  • 11. Competitive inhibition of hepatic sterol 27-hydroxylase by sitosterol: decreased activity in sitosterolemia.
    Nguyen LB, Shefer S, Salen G, Tint SG, Batta AK.
    Proc Assoc Am Physicians; 1998 Feb 20; 110(1):32-9. PubMed ID: 9460081
    [Abstract] [Full Text] [Related]

  • 12. Comparative effect of dietary sitosterol on plasma sterols and cholesterol and bile acid synthesis in a sitosterolemic homozygote and heterozygote subject.
    Cobb MM, Salen G, Tint GS.
    J Am Coll Nutr; 1997 Dec 20; 16(6):605-13. PubMed ID: 9430090
    [Abstract] [Full Text] [Related]

  • 13. A molecular defect in hepatic cholesterol biosynthesis in sitosterolemia with xanthomatosis.
    Nguyen LB, Shefer S, Salen G, Ness GC, Tint GS, Zaki FG, Rani I.
    J Clin Invest; 1990 Sep 20; 86(3):923-31. PubMed ID: 2394840
    [Abstract] [Full Text] [Related]

  • 14. Stimulation of the proliferation of the Madin-Darby canine kidney (MDCK) epithelial cell line by high-density lipoproteins and their induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity.
    Gospodarowicz D, Cohen DC, Massoglia SL.
    J Cell Physiol; 1983 Oct 20; 117(1):76-90. PubMed ID: 6352714
    [Abstract] [Full Text] [Related]

  • 15. Down-regulation of cholesterol biosynthesis in sitosterolemia: diminished activities of acetoacetyl-CoA thiolase, 3-hydroxy-3-methylglutaryl-CoA synthase, reductase, squalene synthase, and 7-dehydrocholesterol delta7-reductase in liver and mononuclear leukocytes.
    Honda A, Salen G, Nguyen LB, Tint GS, Batta AK, Shefer S.
    J Lipid Res; 1998 Jan 20; 39(1):44-50. PubMed ID: 9469584
    [Abstract] [Full Text] [Related]

  • 16. Regulation of cholesterol biosynthesis in sitosterolemia: effects of lovastatin, cholestyramine, and dietary sterol restriction.
    Nguyen LB, Cobb M, Shefer S, Salen G, Ness GC, Tint GS.
    J Lipid Res; 1991 Dec 20; 32(12):1941-8. PubMed ID: 1816322
    [Abstract] [Full Text] [Related]

  • 17. Regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity in mouse peritoneal macrophages.
    Angelin B.
    Biochem J; 1988 Oct 15; 255(2):529-34. PubMed ID: 3202831
    [Abstract] [Full Text] [Related]

  • 18. Regulation of sterol synthesis and of 3-hydroxy-3-methylglutaryl coenzyme A reductase by lipoproteins in glial cells in primary culture.
    Langan TJ, Iimori Y, White G, Volpe JJ.
    J Neurosci Res; 1987 Oct 15; 17(4):361-6. PubMed ID: 2887663
    [Abstract] [Full Text] [Related]

  • 19. [Activities of 3-hydroxy-3-methylglutaryl-CoA reductase and acetyl-CoA carboxylase and rate of biosynthesis of mevalonic acid, squalene, sterols and fatty acids from [1-14C]acetyl-CoA and [2-14C]malonyl-CoA in rat liver: changes induced by daily rhythm].
    Poliakova ED, Dizhe EB, Klimova TA, Denisenko TV, Vasil'eva LE.
    Biokhimiia; 1981 Jan 15; 46(1):126-39. PubMed ID: 6113851
    [Abstract] [Full Text] [Related]

  • 20. Unexpected failure of bile acid malabsorption to stimulate cholesterol synthesis in sitosterolemia with xanthomatosis. Comparison with lovastatin.
    Nguyen L, Salen G, Shefer S, Shore V, Tint GS, Ness G.
    Arteriosclerosis; 1990 Jan 15; 10(2):289-97. PubMed ID: 2317163
    [Abstract] [Full Text] [Related]

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