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355 related items for PubMed ID: 11600673

  • 1. cAMP-regulated guanine nucleotide exchange factor II (Epac2) mediates Ca2+-induced Ca2+ release in INS-1 pancreatic beta-cells.
    Kang G, Chepurny OG, Holz GG.
    J Physiol; 2001 Oct 15; 536(Pt 2):375-85. PubMed ID: 11600673
    [Abstract] [Full Text] [Related]

  • 2. A cAMP and Ca2+ coincidence detector in support of Ca2+-induced Ca2+ release in mouse pancreatic beta cells.
    Kang G, Chepurny OG, Rindler MJ, Collis L, Chepurny Z, Li WH, Harbeck M, Roe MW, Holz GG.
    J Physiol; 2005 Jul 01; 566(Pt 1):173-88. PubMed ID: 15860526
    [Abstract] [Full Text] [Related]

  • 3. cAMP-dependent mobilization of intracellular Ca2+ stores by activation of ryanodine receptors in pancreatic beta-cells. A Ca2+ signaling system stimulated by the insulinotropic hormone glucagon-like peptide-1-(7-37).
    Holz GG, Leech CA, Heller RS, Castonguay M, Habener JF.
    J Biol Chem; 1999 May 14; 274(20):14147-56. PubMed ID: 10318832
    [Abstract] [Full Text] [Related]

  • 4. Epac2-dependent mobilization of intracellular Ca²+ by glucagon-like peptide-1 receptor agonist exendin-4 is disrupted in β-cells of phospholipase C-ε knockout mice.
    Dzhura I, Chepurny OG, Kelley GG, Leech CA, Roe MW, Dzhura E, Afshari P, Malik S, Rindler MJ, Xu X, Lu Y, Smrcka AV, Holz GG.
    J Physiol; 2010 Dec 15; 588(Pt 24):4871-89. PubMed ID: 21041529
    [Abstract] [Full Text] [Related]

  • 5. Ca2+ influx through L-type Ca2+ channels and Ca2+-induced Ca2+ release regulate cAMP accumulation and Epac1-dependent ERK 1/2 activation in INS-1 cells.
    Pratt EP, Salyer AE, Guerra ML, Hockerman GH.
    Mol Cell Endocrinol; 2016 Jan 05; 419():60-71. PubMed ID: 26435461
    [Abstract] [Full Text] [Related]

  • 6. Calcium/calmodulin-dependent serine protein kinase is involved in exendin-4-induced insulin secretion in INS-1 cells.
    Zhu ZQ, Wang D, Xiang D, Yuan YX, Wang Y.
    Metabolism; 2014 Jan 05; 63(1):120-6. PubMed ID: 24140090
    [Abstract] [Full Text] [Related]

  • 7. Exendin-4 as a stimulator of rat insulin I gene promoter activity via bZIP/CRE interactions sensitive to serine/threonine protein kinase inhibitor Ro 31-8220.
    Chepurny OG, Hussain MA, Holz GG.
    Endocrinology; 2002 Jun 05; 143(6):2303-13. PubMed ID: 12021195
    [Abstract] [Full Text] [Related]

  • 8. cAMP Dose-dependently prevents palmitate-induced apoptosis by both protein kinase A- and cAMP-guanine nucleotide exchange factor-dependent pathways in beta-cells.
    Kwon G, Pappan KL, Marshall CA, Schaffer JE, McDaniel ML.
    J Biol Chem; 2004 Mar 05; 279(10):8938-45. PubMed ID: 14688288
    [Abstract] [Full Text] [Related]

  • 9. Receptor (MT(1)) mediated influence of melatonin on cAMP concentration and insulin secretion of rat insulinoma cells INS-1.
    Peschke E, Mühlbauer E, Musshoff U, Csernus VJ, Chankiewitz E, Peschke D.
    J Pineal Res; 2002 Sep 05; 33(2):63-71. PubMed ID: 12153439
    [Abstract] [Full Text] [Related]

  • 10. cAMP sensor Epac as a determinant of ATP-sensitive potassium channel activity in human pancreatic beta cells and rat INS-1 cells.
    Kang G, Chepurny OG, Malester B, Rindler MJ, Rehmann H, Bos JL, Schwede F, Coetzee WA, Holz GG.
    J Physiol; 2006 Jun 15; 573(Pt 3):595-609. PubMed ID: 16613879
    [Abstract] [Full Text] [Related]

  • 11. Glucagon-like peptide 1 potentiates glucotoxicity-diminished insulin secretion via stimulation of cAMP-PKA signaling in INS-1E cells and mouse islets.
    Luo G, Kong X, Lu L, Xu X, Wang H, Ma X.
    Int J Biochem Cell Biol; 2013 Feb 15; 45(2):483-90. PubMed ID: 23220045
    [Abstract] [Full Text] [Related]

  • 12. Glucagon-like peptide-1 mobilizes intracellular Ca2+ and stimulates mitochondrial ATP synthesis in pancreatic MIN6 beta-cells.
    Tsuboi T, da Silva Xavier G, Holz GG, Jouaville LS, Thomas AP, Rutter GA.
    Biochem J; 2003 Jan 15; 369(Pt 2):287-99. PubMed ID: 12410638
    [Abstract] [Full Text] [Related]

  • 13. cAMP-signaling pathway acts in selective synergism with glucose or tolbutamide to increase cytosolic Ca2+ in rat pancreatic beta-cells.
    Yaekura K, Kakei M, Yada T.
    Diabetes; 1996 Mar 15; 45(3):295-301. PubMed ID: 8593933
    [Abstract] [Full Text] [Related]

  • 14. Ca(2+)-induced Ca(2+) release via inositol 1,4,5-trisphosphate receptors is amplified by protein kinase A and triggers exocytosis in pancreatic beta-cells.
    Dyachok O, Gylfe E.
    J Biol Chem; 2004 Oct 29; 279(44):45455-61. PubMed ID: 15316011
    [Abstract] [Full Text] [Related]

  • 15. Glucagon-like peptide I increases cytoplasmic calcium in insulin-secreting beta TC3-cells by enhancement of intracellular calcium mobilization.
    Gromada J, Dissing S, Bokvist K, Renström E, Frøkjaer-Jensen J, Wulff BS, Rorsman P.
    Diabetes; 1995 Jul 29; 44(7):767-74. PubMed ID: 7789644
    [Abstract] [Full Text] [Related]

  • 16. Differential modulation of Cav1.2 and Cav1.3-mediated glucose-stimulated insulin secretion by cAMP in INS-1 cells: distinct roles for exchange protein directly activated by cAMP 2 (Epac2) and protein kinase A.
    Liu G, Jacobo SM, Hilliard N, Hockerman GH.
    J Pharmacol Exp Ther; 2006 Jul 29; 318(1):152-60. PubMed ID: 16565168
    [Abstract] [Full Text] [Related]

  • 17. In situ activation of the type 2 ryanodine receptor in pancreatic beta cells requires cAMP-dependent phosphorylation.
    Islam MS, Leibiger I, Leibiger B, Rossi D, Sorrentino V, Ekström TJ, Westerblad H, Andrade FH, Berggren PO.
    Proc Natl Acad Sci U S A; 1998 May 26; 95(11):6145-50. PubMed ID: 9600932
    [Abstract] [Full Text] [Related]

  • 18. Exendin-4 overcomes cytokine-induced decreases in gap junction coupling via protein kinase A and Epac2 in mouse and human islets.
    Farnsworth NL, Walter R, Piscopio RA, Schleicher WE, Benninger RKP.
    J Physiol; 2019 Jan 26; 597(2):431-447. PubMed ID: 30412665
    [Abstract] [Full Text] [Related]

  • 19. cAMP signaling through protein kinase A and Epac2 induces substance P release in the rat spinal cord.
    Chen W, McRoberts JA, Ennes HS, Marvizon JC.
    Neuropharmacology; 2021 May 15; 189():108533. PubMed ID: 33744339
    [Abstract] [Full Text] [Related]

  • 20. cAMP increases Ca2+-dependent exocytosis through both PKA and Epac2 in mouse melanotrophs from pituitary tissue slices.
    Sedej S, Rose T, Rupnik M.
    J Physiol; 2005 Sep 15; 567(Pt 3):799-813. PubMed ID: 15994184
    [Abstract] [Full Text] [Related]

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