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Journal Abstract Search

126 related items for PubMed ID: 11602611

  • 1. Structure-function investigation of the interaction of 1- and 2-substituted 3-hydroxypyridin-4-ones with 5-lipoxygenase and ribonucleotide reductase.
    Kayyali R, Porter JB, Liu ZD, Davies NA, Nugent JH, Cooper CE, Hider RC.
    J Biol Chem; 2001 Dec 28; 276(52):48814-22. PubMed ID: 11602611
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  • 2. Design, synthesis, and evaluation of novel 2-substituted 3-hydroxypyridin-4-ones: structure-activity investigation of metalloenzyme inhibition by iron chelators.
    Liu ZD, Kayyali R, Hider RC, Porter JB, Theobald AE.
    J Med Chem; 2002 Jan 31; 45(3):631-9. PubMed ID: 11806714
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  • 3. The relationship of intracellular iron chelation to the inhibition and regeneration of human ribonucleotide reductase.
    Cooper CE, Lynagh GR, Hoyes KP, Hider RC, Cammack R, Porter JB.
    J Biol Chem; 1996 Aug 23; 271(34):20291-9. PubMed ID: 8702762
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  • 4. Cell cycle synchronization and growth inhibition by 3-hydroxypyridin-4-one iron chelators in leukemia cell lines.
    Hoyes KP, Hider RC, Porter JB.
    Cancer Res; 1992 Sep 01; 52(17):4591-9. PubMed ID: 1511427
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  • 5. Subcellular distribution of desferrioxamine and hydroxypyridin-4-one chelators in K562 cells affects chelation of intracellular iron pools.
    Hoyes KP, Porter JB.
    Br J Haematol; 1993 Oct 01; 85(2):393-400. PubMed ID: 8280612
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  • 7. Effect on ribonucleotide reductase of novel lipophilic iron chelators: the desferri-exochelins.
    Hodges YK, Antholine WE, Horwitz LD.
    Biochem Biophys Res Commun; 2004 Mar 12; 315(3):595-8. PubMed ID: 14975742
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  • 8. In vivo and in vitro effects of 3-hydroxypyridin-4-one chelators on murine hemopoiesis.
    Hoyes KP, Jones HM, Abeysinghe RD, Hider RC, Porter JB.
    Exp Hematol; 1993 Jan 12; 21(1):86-92. PubMed ID: 8417963
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  • 9. Cellular zinc content is a major determinant of iron chelator-induced apoptosis of thymocytes.
    Maclean KH, Cleveland JL, Porter JB.
    Blood; 2001 Dec 15; 98(13):3831-9. PubMed ID: 11739193
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  • 12. Antioxidant and free radical scavenging activities of the iron chelators pyoverdin and hydroxypyrid-4-ones in iron-loaded hepatocyte cultures: comparison of their mechanism of protection with that of desferrioxamine.
    Morel I, Cillard J, Lescoat G, Sergent O, Pasdeloup N, Ocaktan AZ, Abdallah MA, Brissot P, Cillard P.
    Free Radic Biol Med; 1992 Nov 15; 13(5):499-508. PubMed ID: 1334028
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  • 14. Inhibition of iron toxicity in rat and human hepatocyte cultures by the hydroxypyridin-4-ones CP20 and CP94.
    Chenoufi N, Hubert N, Loréal O, Morel I, Pasdeloup N, Cillard J, Brissot P, Lescoat G.
    J Hepatol; 1995 Aug 15; 23(2):166-73. PubMed ID: 7499788
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  • 15. Multidentate pyridinones inhibit the metabolism of nontransferrin-bound iron by hepatocytes and hepatoma cells.
    Chua AC, Ingram HA, Raymond KN, Baker E.
    Eur J Biochem; 2003 Apr 15; 270(8):1689-98. PubMed ID: 12694182
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  • 17. Structure-activity investigation of the inhibition of 3-hydroxypyridin-4-ones on mammalian tyrosine hydroxylase.
    Liu ZD, Lockwood M, Rose S, Theobald AE, Hider RC.
    Biochem Pharmacol; 2001 Feb 01; 61(3):285-90. PubMed ID: 11172732
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  • 19. Iron mobilization from hepatocyte monolayer cultures by chelators: the importance of membrane permeability and the iron-binding constant.
    Porter JB, Gyparaki M, Burke LC, Huehns ER, Sarpong P, Saez V, Hider RC.
    Blood; 1988 Nov 01; 72(5):1497-503. PubMed ID: 3179437
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