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Journal Abstract Search

218 related items for PubMed ID: 11602820

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  • 2. Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: evidence for a provisional safety margin in drug development.
    Redfern WS, Carlsson L, Davis AS, Lynch WG, MacKenzie I, Palethorpe S, Siegl PK, Strang I, Sullivan AT, Wallis R, Camm AJ, Hammond TG.
    Cardiovasc Res; 2003 Apr 01; 58(1):32-45. PubMed ID: 12667944
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  • 4. Modulation of HERG potassium channels by extracellular magnesium and quinidine.
    Po SS, Wang DW, Yang IC, Johnson JP, Nie L, Bennett PB.
    J Cardiovasc Pharmacol; 1999 Feb 01; 33(2):181-5. PubMed ID: 10028924
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  • 5. Testosterone-mediated modulation of HERG blockade by proarrhythmic agents.
    Shuba YM, Degtiar VE, Osipenko VN, Naidenov VG, Woosley RL.
    Biochem Pharmacol; 2001 Jul 01; 62(1):41-9. PubMed ID: 11377395
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  • 7. [Electropharmacological assessment of the risk of drug-induced long-QT syndrome using native cardiac cells and cultured cells expressing HERG channels].
    Nakaya H.
    Nihon Yakurigaku Zasshi; 2003 Jun 01; 121(6):384-92. PubMed ID: 12835532
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  • 8. Comparative pharmacology of guinea pig cardiac myocyte and cloned hERG (I(Kr)) channel.
    Davie C, Pierre-Valentin J, Pollard C, Standen N, Mitcheson J, Alexander P, Thong B.
    J Cardiovasc Electrophysiol; 2004 Nov 01; 15(11):1302-9. PubMed ID: 15574182
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  • 12. High-affinity blockade of human ether-a-go-go-related gene human cardiac potassium channels by the novel antiarrhythmic drug BRL-32872.
    Thomas D, Wendt-Nordahl G, Röckl K, Ficker E, Brown AM, Kiehn J.
    J Pharmacol Exp Ther; 2001 May 01; 297(2):753-61. PubMed ID: 11303067
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  • 13. Physicochemical determinants for drug induced blockade of HERG potassium channels: effect of charge and charge shielding.
    Zolotoy AB, Plouvier BP, Beatch GB, Hayes ES, Wall RA, Walker MJ.
    Curr Med Chem Cardiovasc Hematol Agents; 2003 Oct 01; 1(3):225-41. PubMed ID: 15326914
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  • 15. A mechanism for the proarrhythmic effects of cisapride (Propulsid): high affinity blockade of the human cardiac potassium channel HERG.
    Rampe D, Roy ML, Dennis A, Brown AM.
    FEBS Lett; 1997 Nov 03; 417(1):28-32. PubMed ID: 9395068
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  • 16. Characterisation of recombinant HERG K+ channel blockade by the Class Ia antiarrhythmic drug procainamide.
    Ridley JM, Milnes JT, Benest AV, Masters JD, Witchel HJ, Hancox JC.
    Biochem Biophys Res Commun; 2003 Jun 27; 306(2):388-93. PubMed ID: 12804575
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