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337 related items for PubMed ID: 11606388

  • 1. Inhibition of growth, invasion, and metastasis of human pancreatic carcinoma cells by NK4 in an orthotopic mouse model.
    Tomioka D, Maehara N, Kuba K, Mizumoto K, Tanaka M, Matsumoto K, Nakamura T.
    Cancer Res; 2001 Oct 15; 61(20):7518-24. PubMed ID: 11606388
    [Abstract] [Full Text] [Related]

  • 2. HGF/NK4, a four-kringle antagonist of hepatocyte growth factor, is an angiogenesis inhibitor that suppresses tumor growth and metastasis in mice.
    Kuba K, Matsumoto K, Date K, Shimura H, Tanaka M, Nakamura T.
    Cancer Res; 2000 Dec 01; 60(23):6737-43. PubMed ID: 11118060
    [Abstract] [Full Text] [Related]

  • 3. Intraperitoneal injection of adenovirus-mediated NK4 gene suppresses peritoneal dissemination of pancreatic cancer cell line AsPC-1 in nude mice.
    Saimura M, Nagai E, Mizumoto K, Maehara N, Okino H, Katano M, Matsumoto K, Nakamura T, Narumi K, Nukiwa T, Tanaka M.
    Cancer Gene Ther; 2002 Oct 01; 9(10):799-806. PubMed ID: 12224019
    [Abstract] [Full Text] [Related]

  • 4. NK4, a four-kringle antagonist of HGF, inhibits spreading and invasion of human pancreatic cancer cells.
    Maehara N, Matsumoto K, Kuba K, Mizumoto K, Tanaka M, Nakamura T.
    Br J Cancer; 2001 Mar 23; 84(6):864-73. PubMed ID: 11259105
    [Abstract] [Full Text] [Related]

  • 5. Hepatic gene expression of NK4, an HGF-antagonist/angiogenesis inhibitor, suppresses liver metastasis and invasive growth of colon cancer in mice.
    Wen J, Matsumoto K, Taniura N, Tomioka D, Nakamura T.
    Cancer Gene Ther; 2004 Jun 23; 11(6):419-30. PubMed ID: 15017381
    [Abstract] [Full Text] [Related]

  • 6. Suppression of tumor growth, invasion and angiogenesis of human gastric cancer by adenovirus-mediated expression of NK4.
    Heideman DA, van Beusechem VW, Bloemena E, Snijders PJ, Craanen ME, Offerhaus GJ, Derksen PW, de Bruin M, Witlox MA, Molenaar B, Meijer CJ, Gerritsen WR.
    J Gene Med; 2004 Mar 23; 6(3):317-27. PubMed ID: 15026993
    [Abstract] [Full Text] [Related]

  • 7. Tumor suppression through angiogenesis inhibition by SUIT-2 pancreatic cancer cells genetically engineered to secrete NK4.
    Saimura M, Nagai E, Mizumoto K, Maehara N, Minamishima YA, Katano M, Matsumoto K, Nakamura T, Tanaka M.
    Clin Cancer Res; 2002 Oct 23; 8(10):3243-9. PubMed ID: 12374695
    [Abstract] [Full Text] [Related]

  • 8. Inhibition of tumor growth and invasion by a four-kringle antagonist (HGF/NK4) for hepatocyte growth factor.
    Date K, Matsumoto K, Kuba K, Shimura H, Tanaka M, Nakamura T.
    Oncogene; 1998 Dec 10; 17(23):3045-54. PubMed ID: 9881707
    [Abstract] [Full Text] [Related]

  • 9. Targeting of urokinase plasminogen activator receptor in human pancreatic carcinoma cells inhibits c-Met- and insulin-like growth factor-I receptor-mediated migration and invasion and orthotopic tumor growth in mice.
    Bauer TW, Liu W, Fan F, Camp ER, Yang A, Somcio RJ, Bucana CD, Callahan J, Parry GC, Evans DB, Boyd DD, Mazar AP, Ellis LM.
    Cancer Res; 2005 Sep 01; 65(17):7775-81. PubMed ID: 16140945
    [Abstract] [Full Text] [Related]

  • 10. Inhibition of intracerebral glioblastoma growth by local treatment with the scatter factor/hepatocyte growth factor-antagonist NK4.
    Brockmann MA, Papadimitriou A, Brandt M, Fillbrandt R, Westphal M, Lamszus K.
    Clin Cancer Res; 2003 Oct 01; 9(12):4578-85. PubMed ID: 14555533
    [Abstract] [Full Text] [Related]

  • 11. Inhibition of angiogenesis and HGF-cMET-elicited malignant processes in human hepatocellular carcinoma cells using adenoviral vector-mediated NK4 gene therapy.
    Heideman DA, Overmeer RM, van Beusechem VW, Lamers WH, Hakvoort TB, Snijders PJ, Craanen ME, Offerhaus GJ, Meijer CJ, Gerritsen WR.
    Cancer Gene Ther; 2005 Dec 01; 12(12):954-62. PubMed ID: 15905856
    [Abstract] [Full Text] [Related]

  • 12. Adenoviral-mediated gene transduction of the hepatocyte growth factor (HGF) antagonist, NK4, suppresses peritoneal metastases of gastric cancer in nude mice.
    Ueda K, Iwahashi M, Matsuura I, Nakamori M, Nakamura M, Ojima T, Naka T, Ishida K, Matsumoto K, Nakamura T, Yamaue H.
    Eur J Cancer; 2004 Sep 01; 40(14):2135-42. PubMed ID: 15341989
    [Abstract] [Full Text] [Related]

  • 13. [Effect of transferred NK4 gene on biological characteristics of human pancreatic cancer cell line SW1990].
    Lai RX, Yuan SZ, Nakamura T.
    Ai Zheng; 2004 Oct 01; 23(10):1134-8. PubMed ID: 15473922
    [Abstract] [Full Text] [Related]

  • 14. Mechanisms and significance of bifunctional NK4 in cancer treatment.
    Matsumoto K, Nakamura T.
    Biochem Biophys Res Commun; 2005 Jul 29; 333(2):316-27. PubMed ID: 15950947
    [Abstract] [Full Text] [Related]

  • 15. Hepatocyte growth factor and Met in tumor biology and therapeutic approach with NK4.
    Matsumoto K, Nakamura T, Sakai K, Nakamura T.
    Proteomics; 2008 Aug 29; 8(16):3360-70. PubMed ID: 18646008
    [Abstract] [Full Text] [Related]

  • 16. [Effect of NK4 gene transfection on tumor growth of human pancreatic cancer xenograft in nude mice].
    Lai RX, Zhang SN, Nakamura T, Yuan SZ.
    Ai Zheng; 2005 Oct 29; 24(10):1191-5. PubMed ID: 16219131
    [Abstract] [Full Text] [Related]

  • 17. Systemic NK4 gene therapy inhibits tumor growth and metastasis of melanoma and lung carcinoma in syngeneic mouse tumor models.
    Kishi Y, Kuba K, Nakamura T, Wen J, Suzuki Y, Mizuno S, Nukiwa T, Matsumoto K, Nakamura T.
    Cancer Sci; 2009 Jul 29; 100(7):1351-8. PubMed ID: 19438869
    [Abstract] [Full Text] [Related]

  • 18. Inhibition of colon cancer growth and metastasis by NK4 gene repetitive delivery in mice.
    Wen J, Matsumoto K, Taniura N, Tomioka D, Nakamura T.
    Biochem Biophys Res Commun; 2007 Jun 22; 358(1):117-23. PubMed ID: 17467663
    [Abstract] [Full Text] [Related]

  • 19. The HGF/SF-induced phosphorylation of paxillin, matrix adhesion, and invasion of prostate cancer cells were suppressed by NK4, an HGF/SF variant.
    Parr C, Davies G, Nakamura T, Matsumoto K, Mason MD, Jiang WG.
    Biochem Biophys Res Commun; 2001 Aug 03; 285(5):1330-7. PubMed ID: 11478803
    [Abstract] [Full Text] [Related]

  • 20. Gallbladder cancer treatment using adenovirus expressing the HGF/NK4 gene in a peritoneal implantation model.
    Tanaka T, Shimura H, Sasaki T, Narumi K, Maemondo M, Nukiwa T, Matsumoto K, Nakamura T, Ikeda S.
    Cancer Gene Ther; 2004 Jun 03; 11(6):431-40. PubMed ID: 15118756
    [Abstract] [Full Text] [Related]

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