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PUBMED FOR HANDHELDS

Journal Abstract Search


299 related items for PubMed ID: 11667041

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  • 3. Evaluation of functional analogs of CC-1065 and the duocarmycins incorporating the cross-linking 9a-chloromethyl-1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-on e (C2BI) alkylation subunit.
    Boger DL, Johnson DS, Palanki MS, Kitos PA, Chang J, Dowell P.
    Bioorg Med Chem; 1993 Jul; 1(1):27-38. PubMed ID: 8081835
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  • 4. Selective metal cation activation of a DNA alkylating agent: synthesis and evaluation of methyl 1,2,9, 9a-Tetrahydrocyclopropa[c]pyrido[3,2-e]indol-4-one-7-carboxylate (CPyI).
    Boger DL, Boyce CW.
    J Org Chem; 2000 Jun 30; 65(13):4088-100. PubMed ID: 10866626
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  • 5. 1,2,9,9a-Tetrahydrocyclopropa[c]benz[e]indol-4-one (CBI) analogs of CC-1065 and the duocarmycins: synthesis and evaluation.
    Boger DL, Yun W, Han N.
    Bioorg Med Chem; 1995 Nov 30; 3(11):1429-53. PubMed ID: 8634824
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  • 6. Synthesis and evaluation of 1,2,8, 8a-Tetrahydrocyclopropa[c]pyrrolo[3,2-e]indol-4(5H)-one, the parent alkylation subunit of CC-1065 and the duocarmycins: impact of the alkylation subunit substituents and its implications for DNA alkylation catalysis.
    Boger DL, Santillán A, Searcey M, Brunette SR, Wolkenberg SE, Hedrick MP, Jin Q.
    J Org Chem; 2000 Jun 30; 65(13):4101-11. PubMed ID: 10866627
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  • 7. CBI-CDPBO1 and CBI-CDPBI1: CC-1065 analogs containing deep-seated modifications in the DNA binding subunit.
    Boger DL, Yun W, Cai H, Han N.
    Bioorg Med Chem; 1995 Jun 30; 3(6):761-7. PubMed ID: 7582954
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  • 8. Synthesis and evaluation of a series of C3-substituted CBI analogues of CC-1065 and the duocarmycins.
    Boger DL, Brunette SR, Garbaccio RM.
    J Org Chem; 2001 Jul 27; 66(15):5163-73. PubMed ID: 11463270
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  • 9. Asymmetric synthesis of 1,2,9,9a-tetrahydrocyclopropa[c]benzo[e]indol-4-one (CBI).
    Lajiness JP, Boger DL.
    J Org Chem; 2011 Jan 21; 76(2):583-7. PubMed ID: 21192653
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  • 12. Synthesis and characterization of a cyclobutane duocarmycin derivative incorporating the 1,2,10,11-tetrahydro-9H-cyclobuta[c]benzo[e]indol-4-one (CbBI) alkylation subunit.
    Lajiness JP, Boger DL.
    J Am Chem Soc; 2010 Oct 06; 132(39):13936-40. PubMed ID: 20839806
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  • 13. Parallel synthesis and evaluation of 132 (+)-1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-one (CBI) analogues of CC-1065 and the duocarmycins defining the contribution of the DNA-binding domain.
    Boger DL, Schmitt HW, Fink BE, Hedrick MP.
    J Org Chem; 2001 Oct 05; 66(20):6654-61. PubMed ID: 11578217
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  • 14. Molecular basis for sequence selective DNA alkylation by (+)- and ent-(-)-CC-1065 and related agents: alkylation site models that accommodate the offset AT-rich adenine N3 alkylation selectivity.
    Boger DL, Johnson DS, Yun W, Tarby CM.
    Bioorg Med Chem; 1994 Feb 05; 2(2):115-35. PubMed ID: 7922122
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  • 15. Synthesis of pyrrole-imidazole polyamide seco-1-chloromethyl-5-hydroxy-1,2-dihydro-3h-benz[e]indole conjugates with a vinyl linker recognizing a 7 bp DNA sequence.
    Takagaki T, Bando T, Sugiyama H.
    J Am Chem Soc; 2012 Aug 08; 134(31):13074-81. PubMed ID: 22799887
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  • 16. Are the Duocarmycin and CC-1065 DNA Alkylation Reactions Acid-Catalyzed? Solvolysis pH-Rate Profiles Suggest They Are Not.
    Boger DL, Garbaccio RM.
    J Org Chem; 1999 Jul 23; 64(15):5666-5669. PubMed ID: 11674637
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  • 17. CC-1065 and the duocarmycins: unraveling the keys to a new class of naturally derived DNA alkylating agents.
    Boger DL, Johnson DS.
    Proc Natl Acad Sci U S A; 1995 Apr 25; 92(9):3642-9. PubMed ID: 7731958
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  • 18. Rational design, synthesis, and evaluation of key analogues of CC-1065 and the duocarmycins.
    Tichenor MS, MacMillan KS, Stover JS, Wolkenberg SE, Pavani MG, Zanella L, Zaid AN, Spalluto G, Rayl TJ, Hwang I, Baraldi PG, Boger DL.
    J Am Chem Soc; 2007 Nov 14; 129(45):14092-9. PubMed ID: 17948994
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