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2. Impaired integrin-mediated signal transduction, altered cytoskeletal structure and reduced motility in Hck/Fgr deficient macrophages. Suen PW, Ilic D, Caveggion E, Berton G, Damsky CH, Lowell CA. J Cell Sci; 1999 Nov; 112 ( Pt 22)():4067-78. PubMed ID: 10547366 [Abstract] [Full Text] [Related]
3. The Src family kinases Hck and Fgr are dispensable for inside-out, chemoattractant-induced signaling regulating beta 2 integrin affinity and valency in neutrophils, but are required for beta 2 integrin-mediated outside-in signaling involved in sustained adhesion. Giagulli C, Ottoboni L, Caveggion E, Rossi B, Lowell C, Constantin G, Laudanna C, Berton G. J Immunol; 2006 Jul 01; 177(1):604-11. PubMed ID: 16785558 [Abstract] [Full Text] [Related]
5. Deficiency of Src family kinases p59/61hck and p58c-fgr results in defective adhesion-dependent neutrophil functions. Lowell CA, Fumagalli L, Berton G. J Cell Biol; 1996 May 01; 133(4):895-910. PubMed ID: 8666673 [Abstract] [Full Text] [Related]
6. Fgr but not Syk tyrosine kinase is a target for beta 2 integrin-induced c-Cbl-mediated ubiquitination in adherent human neutrophils. Melander F, Andersson T, Dib K. Biochem J; 2003 Mar 01; 370(Pt 2):687-94. PubMed ID: 12435267 [Abstract] [Full Text] [Related]
7. Adhesion-dependent degranulation of neutrophils requires the Src family kinases Fgr and Hck. Mócsai A, Ligeti E, Lowell CA, Berton G. J Immunol; 1999 Jan 15; 162(2):1120-6. PubMed ID: 9916742 [Abstract] [Full Text] [Related]
8. Signaling by adhesion in human neutrophils: activation of the p72syk tyrosine kinase and formation of protein complexes containing p72syk and Src family kinases in neutrophils spreading over fibrinogen. Yan SR, Huang M, Berton G. J Immunol; 1997 Feb 15; 158(4):1902-10. PubMed ID: 9029132 [Abstract] [Full Text] [Related]
9. Differential involvement of Src family kinases in Fc gamma receptor-mediated phagocytosis. Suzuki T, Kono H, Hirose N, Okada M, Yamamoto T, Yamamoto K, Honda Z. J Immunol; 2000 Jul 01; 165(1):473-82. PubMed ID: 10861086 [Abstract] [Full Text] [Related]
10. A beta 1 integrin signaling pathway involving Src-family kinases, Cbl and PI-3 kinase is required for macrophage spreading and migration. Meng F, Lowell CA. EMBO J; 1998 Aug 03; 17(15):4391-403. PubMed ID: 9687507 [Abstract] [Full Text] [Related]
11. Syk is required for integrin signaling in neutrophils. Mócsai A, Zhou M, Meng F, Tybulewicz VL, Lowell CA. Immunity; 2002 Apr 03; 16(4):547-58. PubMed ID: 11970878 [Abstract] [Full Text] [Related]
12. Coordinate interactions of Csk, Src, and Syk kinases with [alpha]IIb[beta]3 initiate integrin signaling to the cytoskeleton. Obergfell A, Eto K, Mocsai A, Buensuceso C, Moores SL, Brugge JS, Lowell CA, Shattil SJ. J Cell Biol; 2002 Apr 15; 157(2):265-75. PubMed ID: 11940607 [Abstract] [Full Text] [Related]
13. CD45 regulates Src family member kinase activity associated with macrophage integrin-mediated adhesion. Roach T, Slater S, Koval M, White L, Cahir McFarland ED, Okumura M, Thomas M, Brown E. Curr Biol; 1997 Jun 01; 7(6):408-17. PubMed ID: 9197241 [Abstract] [Full Text] [Related]
15. A role for Syk-kinase in the control of the binding cycle of the beta2 integrins (CD11/CD18) in human polymorphonuclear neutrophils. Willeke T, Schymeinsky J, Prange P, Zahler S, Walzog B. J Leukoc Biol; 2003 Aug 01; 74(2):260-9. PubMed ID: 12885943 [Abstract] [Full Text] [Related]
16. Fcgamma receptor-mediated phagocytosis in macrophages lacking the Src family tyrosine kinases Hck, Fgr, and Lyn. Fitzer-Attas CJ, Lowry M, Crowley MT, Finn AJ, Meng F, DeFranco AL, Lowell CA. J Exp Med; 2000 Feb 21; 191(4):669-82. PubMed ID: 10684859 [Abstract] [Full Text] [Related]
18. The Src family kinases Hck and Fgr negatively regulate neutrophil and dendritic cell chemokine signaling via PIR-B. Zhang H, Meng F, Chu CL, Takai T, Lowell CA. Immunity; 2005 Feb 21; 22(2):235-46. PubMed ID: 15723811 [Abstract] [Full Text] [Related]
19. Pre-T cell receptor signals are responsible for the down-regulation of Syk protein tyrosine kinase expression. Chu DH, van Oers NS, Malissen M, Harris J, Elder M, Weiss A. J Immunol; 1999 Sep 01; 163(5):2610-20. PubMed ID: 10453000 [Abstract] [Full Text] [Related]
20. Resistance to endotoxic shock and reduced neutrophil migration in mice deficient for the Src-family kinases Hck and Fgr. Lowell CA, Berton G. Proc Natl Acad Sci U S A; 1998 Jun 23; 95(13):7580-4. PubMed ID: 9636192 [Abstract] [Full Text] [Related] Page: [Next] [New Search]