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255 related items for PubMed ID: 11689692

  • 1. Construction and analysis of mouse strains lacking the ubiquitin ligase UBR1 (E3alpha) of the N-end rule pathway.
    Kwon YT, Xia Z, Davydov IV, Lecker SH, Varshavsky A.
    Mol Cell Biol; 2001 Dec; 21(23):8007-21. PubMed ID: 11689692
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  • 2. The mouse and human genes encoding the recognition component of the N-end rule pathway.
    Kwon YT, Reiss Y, Fried VA, Hershko A, Yoon JK, Gonda DK, Sangan P, Copeland NG, Jenkins NA, Varshavsky A.
    Proc Natl Acad Sci U S A; 1998 Jul 07; 95(14):7898-903. PubMed ID: 9653112
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  • 3. Pairs of dipeptides synergistically activate the binding of substrate by ubiquitin ligase through dissociation of its autoinhibitory domain.
    Du F, Navarro-Garcia F, Xia Z, Tasaki T, Varshavsky A.
    Proc Natl Acad Sci U S A; 2002 Oct 29; 99(22):14110-5. PubMed ID: 12391316
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  • 5. Behavioral characterization of mice lacking the ubiquitin ligase UBR1 of the N-end rule pathway.
    Balogh SA, McDowell CS, Denenberg VH.
    Genes Brain Behav; 2002 Nov 29; 1(4):223-9. PubMed ID: 12882367
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  • 6. Female lethality and apoptosis of spermatocytes in mice lacking the UBR2 ubiquitin ligase of the N-end rule pathway.
    Kwon YT, Xia Z, An JY, Tasaki T, Davydov IV, Seo JW, Sheng J, Xie Y, Varshavsky A.
    Mol Cell Biol; 2003 Nov 29; 23(22):8255-71. PubMed ID: 14585983
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  • 7. Impaired neurogenesis and cardiovascular development in mice lacking the E3 ubiquitin ligases UBR1 and UBR2 of the N-end rule pathway.
    An JY, Seo JW, Tasaki T, Lee MJ, Varshavsky A, Kwon YT.
    Proc Natl Acad Sci U S A; 2006 Apr 18; 103(16):6212-7. PubMed ID: 16606826
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  • 13. Role of N-end rule ubiquitin ligases UBR1 and UBR2 in regulating the leucine-mTOR signaling pathway.
    Kume K, Iizumi Y, Shimada M, Ito Y, Kishi T, Yamaguchi Y, Handa H.
    Genes Cells; 2010 Apr 01; 15(4):339-49. PubMed ID: 20298436
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  • 14. Altered activity, social behavior, and spatial memory in mice lacking the NTAN1p amidase and the asparagine branch of the N-end rule pathway.
    Kwon YT, Balogh SA, Davydov IV, Kashina AS, Yoon JK, Xie Y, Gaur A, Hyde L, Denenberg VH, Varshavsky A.
    Mol Cell Biol; 2000 Jun 01; 20(11):4135-48. PubMed ID: 10805755
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  • 15. The N-end rule pathway is required for import of histidine in yeast lacking the kinesin-like protein Cin8p.
    Xie Y, Varshavsky A.
    Curr Genet; 1999 Sep 01; 36(3):113-23. PubMed ID: 10501933
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  • 17. The N-end rule is mediated by the UBC2(RAD6) ubiquitin-conjugating enzyme.
    Dohmen RJ, Madura K, Bartel B, Varshavsky A.
    Proc Natl Acad Sci U S A; 1991 Aug 15; 88(16):7351-5. PubMed ID: 1651502
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  • 18. Five enzymes of the Arg/N-degron pathway form a targeting complex: The concept of superchanneling.
    Oh JH, Hyun JY, Chen SJ, Varshavsky A.
    Proc Natl Acad Sci U S A; 2020 May 19; 117(20):10778-10788. PubMed ID: 32366662
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  • 19. Peptides accelerate their uptake by activating a ubiquitin-dependent proteolytic pathway.
    Turner GC, Du F, Varshavsky A.
    Nature; 2000 Jun 01; 405(6786):579-83. PubMed ID: 10850718
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  • 20. Ser(120) of Ubc2/Rad6 regulates ubiquitin-dependent N-end rule targeting by E3{alpha}/Ubr1.
    Kumar B, Lecompte KG, Klein JM, Haas AL.
    J Biol Chem; 2010 Dec 31; 285(53):41300-9. PubMed ID: 21041297
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