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191 related items for PubMed ID: 11691791

  • 1. Reversal of mitomycin C resistance by overexpression of bioreductive enzymes in Chinese hamster ovary cells.
    Baumann RP, Hodnick WF, Seow HA, Belcourt MF, Rockwell S, Sherman DH, Sartorelli AC.
    Cancer Res; 2001 Nov 01; 61(21):7770-6. PubMed ID: 11691791
    [Abstract] [Full Text] [Related]

  • 2. Role of NADPH:cytochrome c reductase and DT-diaphorase in the biotransformation of mitomycin C1.
    Keyes SR, Fracasso PM, Heimbrook DC, Rockwell S, Sligar SG, Sartorelli AC.
    Cancer Res; 1984 Dec 01; 44(12 Pt 1):5638-43. PubMed ID: 6437671
    [Abstract] [Full Text] [Related]

  • 3. The effect of functional groups on reduction and activation of quinone bioreductive agents by DT-diaphorase.
    Fourie J, Oleschuk CJ, Guziec F, Guziec L, Fiterman DJ, Monterrosa C, Begleiter A.
    Cancer Chemother Pharmacol; 2002 Feb 01; 49(2):101-10. PubMed ID: 11862423
    [Abstract] [Full Text] [Related]

  • 4. Role of NAD(P)H:(quinone acceptor) oxidoreductase (DT-diaphorase) in activation of mitomycin C under acidic conditions.
    Begleiter A, Leith MK.
    Mol Pharmacol; 1993 Jul 01; 44(1):210-5. PubMed ID: 8341273
    [Abstract] [Full Text] [Related]

  • 5. Metabolism of bioreductive antitumor compounds by purified rat and human DT-diaphorases.
    Beall HD, Mulcahy RT, Siegel D, Traver RD, Gibson NW, Ross D.
    Cancer Res; 1994 Jun 15; 54(12):3196-201. PubMed ID: 8205540
    [Abstract] [Full Text] [Related]

  • 6. Characterization of a set of Chinese hamster ovary variant cell lines demonstrating differing sensitivity to mitomycin C.
    Kuehl BL, Buchwald M, Rauth AM.
    Oncol Res; 1993 Jun 15; 5(6-7):213-21. PubMed ID: 8123941
    [Abstract] [Full Text] [Related]

  • 7. Expression of DT-diaphorase and cytochrome P450 reductase correlates with mitomycin C activity in human bladder tumors.
    Gan Y, Mo Y, Kalns JE, Lu J, Danenberg K, Danenberg P, Wientjes MG, Au JL.
    Clin Cancer Res; 2001 May 15; 7(5):1313-9. PubMed ID: 11350900
    [Abstract] [Full Text] [Related]

  • 8. Exploring the mechanistic aspects of mitomycin antibiotic bioactivation in Chinese hamster ovary cells overexpressing NADPH:cytochrome C (P-450) reductase and DT-diaphorase.
    Belcourt MF, Hodnick WF, Rockwell S, Sartorelli AC.
    Adv Enzyme Regul; 1998 May 15; 38():111-33. PubMed ID: 9762350
    [Abstract] [Full Text] [Related]

  • 9. Expression of human NAD(P)H: quinone oxidoreductase (DT-diaphorase) in Chinese hamster ovary cells: effect on the toxicity of antitumor quinones.
    Gustafson DL, Beall HD, Bolton EM, Ross D, Waldren CA.
    Mol Pharmacol; 1996 Oct 15; 50(4):728-35. PubMed ID: 8863816
    [Abstract] [Full Text] [Related]

  • 10. [DT-diaphorase].
    Mikami K, Shirakusa T, Tsuruo T.
    Gan To Kagaku Ryoho; 1997 Sep 15; 24(11):1606-10. PubMed ID: 9309161
    [Abstract] [Full Text] [Related]

  • 11. Chinese hamster ovary cell lines resistant to mitomycin C under aerobic but not hypoxic conditions are deficient in DT-diaphorase.
    Dulhanty AM, Whitmore GF.
    Cancer Res; 1991 Apr 01; 51(7):1860-5. PubMed ID: 1900739
    [Abstract] [Full Text] [Related]

  • 12. Activation of mitomycin C by NADPH:cytochrome P-450 reductase.
    Bligh HF, Bartoszek A, Robson CN, Hickson ID, Kasper CB, Beggs JD, Wolf CR.
    Cancer Res; 1990 Dec 15; 50(24):7789-92. PubMed ID: 2123741
    [Abstract] [Full Text] [Related]

  • 13. Role of NAD(P)H:(quinone acceptor) oxidoreductase (DT-diaphorase) in activation of mitomycin C under hypoxia.
    Begleiter A, Robotham E, Leith MK.
    Mol Pharmacol; 1992 Apr 15; 41(4):677-82. PubMed ID: 1373799
    [Abstract] [Full Text] [Related]

  • 14. Cytotoxic potential of monoalkylation products between mitomycins and DNA: studies of decarbamoyl mitomycin C in wild-type and repair-deficient cell lines.
    Rockwell S, Kim SY.
    Oncol Res; 1995 Apr 15; 7(1):39-47. PubMed ID: 7549043
    [Abstract] [Full Text] [Related]

  • 15. Cytotoxic potential of monoalkylation products between mitomycins and DNA: studies of decarbamoyl mitomycin C in wild-type and repair-deficient cell lines.
    Kim SY, Rockwell S.
    Oncol Res; 1995 Apr 15; 7(5):39-47. PubMed ID: 8534933
    [Abstract] [Full Text] [Related]

  • 16. Mitomycin resistance in mammalian cells expressing the bacterial mitomycin C resistance protein MCRA.
    Belcourt MF, Penketh PG, Hodnick WF, Johnson DA, Sherman DH, Rockwell S, Sartorelli AC.
    Proc Natl Acad Sci U S A; 1999 Aug 31; 96(18):10489-94. PubMed ID: 10468636
    [Abstract] [Full Text] [Related]

  • 17. DT-diaphorase as a critical determinant of sensitivity to mitomycin C in human colon and gastric carcinoma cell lines.
    Mikami K, Naito M, Tomida A, Yamada M, Sirakusa T, Tsuruo T.
    Cancer Res; 1996 Jun 15; 56(12):2823-6. PubMed ID: 8665520
    [Abstract] [Full Text] [Related]

  • 18. Reductase enzyme expression across the National Cancer Institute Tumor cell line panel: correlation with sensitivity to mitomycin C and EO9.
    Fitzsimmons SA, Workman P, Grever M, Paull K, Camalier R, Lewis AD.
    J Natl Cancer Inst; 1996 Mar 06; 88(5):259-69. PubMed ID: 8614004
    [Abstract] [Full Text] [Related]

  • 19. The importance of DT-diaphorase in mitomycin C resistance in human colon cancer cell lines.
    Lambert PA, Kang Y, Greaves B, Perry RR.
    J Surg Res; 1998 Dec 06; 80(2):177-81. PubMed ID: 9878310
    [Abstract] [Full Text] [Related]

  • 20. [Mechanism of resistance to mitomycin C in a human bladder cancer cell line].
    Xu B, Sun Y, Singh SV.
    Zhonghua Zhong Liu Za Zhi; 1995 Sep 06; 17(5):343-6. PubMed ID: 8697971
    [Abstract] [Full Text] [Related]

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