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279 related items for PubMed ID: 11694532

  • 1. Differential association of CD45 isoforms with CD4 and CD8 regulates the actions of specific pools of p56lck tyrosine kinase in T cell antigen receptor signal transduction.
    Dornan S, Sebestyen Z, Gamble J, Nagy P, Bodnar A, Alldridge L, Doe S, Holmes N, Goff LK, Beverley P, Szollosi J, Alexander DR.
    J Biol Chem; 2002 Jan 18; 277(3):1912-8. PubMed ID: 11694532
    [Abstract] [Full Text] [Related]

  • 2. The CD45 tyrosine phosphatase regulates CD3-induced signal transduction and T cell development in recombinase-deficient mice: restoration of pre-TCR function by active p56(lck).
    Pingel S, Baker M, Turner M, Holmes N, Alexander DR.
    Eur J Immunol; 1999 Aug 18; 29(8):2376-84. PubMed ID: 10458749
    [Abstract] [Full Text] [Related]

  • 3. The CD45 tyrosine phosphatase regulates specific pools of antigen receptor-associated p59fyn and CD4-associated p56lck tyrosine in human T-cells.
    Biffen M, McMichael-Phillips D, Larson T, Venkitaraman A, Alexander D.
    EMBO J; 1994 Apr 15; 13(8):1920-9. PubMed ID: 8168490
    [Abstract] [Full Text] [Related]

  • 4. CD4, CD8 and the role of CD45 in T-cell activation.
    Ledbetter JA, Deans JP, Aruffo A, Grosmaire LS, Kanner SB, Bolen JB, Schieven GL.
    Curr Opin Immunol; 1993 Jun 15; 5(3):334-40. PubMed ID: 8347296
    [Abstract] [Full Text] [Related]

  • 5. Requirement for kinase activity of CD4-associated p56lck in antibody-triggered T cell signal transduction.
    Chu K, Littman DR.
    J Biol Chem; 1994 Sep 30; 269(39):24095-101. PubMed ID: 7929062
    [Abstract] [Full Text] [Related]

  • 6. CD3-zeta surface expression is required for CD4-p56lck-mediated upregulation of T cell antigen receptor-CD3 signaling in T cells.
    Sancho J, Ledbetter JA, Choi MS, Kanner SB, Deans JP, Terhorst C.
    J Biol Chem; 1992 Apr 15; 267(11):7871-9. PubMed ID: 1532798
    [Abstract] [Full Text] [Related]

  • 7. Tyrosine 192 within the SH2 domain of the Src-protein tyrosine kinase p56Lck regulates T-cell activation independently of Lck/CD45 interactions.
    Kästle M, Merten C, Hartig R, Kaehne T, Liaunardy-Jopeace A, Woessner NM, Schamel WW, James J, Minguet S, Simeoni L, Schraven B.
    Cell Commun Signal; 2020 Nov 23; 18(1):183. PubMed ID: 33225946
    [Abstract] [Full Text] [Related]

  • 8. CD4+ CD45RA+ and CD4+ CD45RO+ T cells differ in their TCR-associated signaling responses.
    Hall SR, Heffernan BM, Thompson NT, Rowan WC.
    Eur J Immunol; 1999 Jul 23; 29(7):2098-106. PubMed ID: 10427972
    [Abstract] [Full Text] [Related]

  • 9. ZAP-70 protein promotes tyrosine phosphorylation of T cell receptor signaling motifs (ITAMs) in immature CD4(+)8(+) thymocytes with limiting p56(lck).
    Ashe JM, Wiest DL, Abe R, Singer A.
    J Exp Med; 1999 Apr 05; 189(7):1163-8. PubMed ID: 10190908
    [Abstract] [Full Text] [Related]

  • 10. Rapid tyrosine phosphorylation of Lck following ligation of the tumor-associated cell surface molecule A6H.
    Labuda T, Gerwien J, Odum N, Dohlsten M.
    Int Immunol; 1999 Mar 05; 11(3):427-33. PubMed ID: 10221654
    [Abstract] [Full Text] [Related]

  • 11. Interaction of CD4:lck with the T cell receptor/CD3 complex induces early signaling events in the absence of CD45 tyrosine phosphatase.
    Deans JP, Kanner SB, Torres RM, Ledbetter JA.
    Eur J Immunol; 1992 Mar 05; 22(3):661-8. PubMed ID: 1532148
    [Abstract] [Full Text] [Related]

  • 12. Age-related impairments in TCR/CD3 activation of ZAP-70 are associated with reduced tyrosine phosphorylations of zeta-chains and p59fyn/p56lck in human T cells.
    Whisler RL, Chen M, Liu B, Newhouse YG.
    Mech Ageing Dev; 1999 Nov 02; 111(1):49-66. PubMed ID: 10576607
    [Abstract] [Full Text] [Related]

  • 13. Syk and ZAP-70 mediate recruitment of p56lck/CD4 to the activated T cell receptor/CD3/zeta complex.
    Thome M, Duplay P, Guttinger M, Acuto O.
    J Exp Med; 1995 Jun 01; 181(6):1997-2006. PubMed ID: 7539035
    [Abstract] [Full Text] [Related]

  • 14. CTLA-4 suppresses proximal TCR signaling in resting human CD4(+) T cells by inhibiting ZAP-70 Tyr(319) phosphorylation: a potential role for tyrosine phosphatases.
    Guntermann C, Alexander DR.
    J Immunol; 2002 May 01; 168(9):4420-9. PubMed ID: 11970985
    [Abstract] [Full Text] [Related]

  • 15. Expression of CD45 lacking the catalytic protein tyrosine phosphatase domain modulates Lck phosphorylation and T cell activation.
    Wang Y, Johnson P.
    J Biol Chem; 2005 Apr 08; 280(14):14318-24. PubMed ID: 15687496
    [Abstract] [Full Text] [Related]

  • 16. Interactions of CD45-associated protein with the antigen receptor signaling machinery in T-lymphocytes.
    Veillette A, Soussou D, Latour S, Davidson D, Gervais FG.
    J Biol Chem; 1999 May 14; 274(20):14392-9. PubMed ID: 10318863
    [Abstract] [Full Text] [Related]

  • 17. CD45 tyrosine phosphatase-activated p59fyn couples the T cell antigen receptor to pathways of diacylglycerol production, protein kinase C activation and calcium influx.
    Shiroo M, Goff L, Biffen M, Shivnan E, Alexander D.
    EMBO J; 1992 Dec 14; 11(13):4887-97. PubMed ID: 1464315
    [Abstract] [Full Text] [Related]

  • 18. Molecular interactions, T-cell subsets and a role of the CD4/CD8:p56lck complex in human T-cell activation.
    Rudd CE, Anderson P, Morimoto C, Streuli M, Schlossman SF.
    Immunol Rev; 1989 Oct 14; 111():225-66. PubMed ID: 2534114
    [Abstract] [Full Text] [Related]

  • 19. The p56lck SH2 domain mediates recruitment of CD8/p56lck to the activated T cell receptor/CD3/zeta complex.
    Thome M, Germain V, DiSanto JP, Acuto O.
    Eur J Immunol; 1996 Sep 14; 26(9):2093-2100. PubMed ID: 8814252
    [Abstract] [Full Text] [Related]

  • 20. Phosphatase CD45 both positively and negatively regulates T cell receptor phosphorylation in reconstituted membrane protein clusters.
    Furlan G, Minowa T, Hanagata N, Kataoka-Hamai C, Kaizuka Y.
    J Biol Chem; 2014 Oct 10; 289(41):28514-25. PubMed ID: 25128530
    [Abstract] [Full Text] [Related]

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