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140 related items for PubMed ID: 11705379

  • 1. Identification of the phosphatidylserine binding site in the C2 domain that is important for PKC alpha activation and in vivo cell localization.
    Conesa-Zamora P, Lopez-Andreo MJ, Gómez-Fernández JC, Corbalán-García S.
    Biochemistry; 2001 Nov 20; 40(46):13898-905. PubMed ID: 11705379
    [Abstract] [Full Text] [Related]

  • 2. Role of the lysine-rich cluster of the C2 domain in the phosphatidylserine-dependent activation of PKCalpha.
    Rodríguez-Alfaro JA, Gomez-Fernandez JC, Corbalan-Garcia S.
    J Mol Biol; 2004 Jan 23; 335(4):1117-29. PubMed ID: 14698304
    [Abstract] [Full Text] [Related]

  • 3. Determination of the calcium-binding sites of the C2 domain of protein kinase Calpha that are critical for its translocation to the plasma membrane.
    Corbalán-García S, Rodríguez-Alfaro JA, Gómez-Fernández JC.
    Biochem J; 1999 Feb 01; 337 ( Pt 3)(Pt 3):513-21. PubMed ID: 9895296
    [Abstract] [Full Text] [Related]

  • 4. Structure of the C2 domain from novel protein kinase Cepsilon. A membrane binding model for Ca(2+)-independent C2 domains.
    Ochoa WF, Garcia-Garcia J, Fita I, Corbalan-Garcia S, Verdaguer N, Gomez-Fernandez JC.
    J Mol Biol; 2001 Aug 24; 311(4):837-49. PubMed ID: 11518534
    [Abstract] [Full Text] [Related]

  • 5. Ca(2+) bridges the C2 membrane-binding domain of protein kinase Calpha directly to phosphatidylserine.
    Verdaguer N, Corbalan-Garcia S, Ochoa WF, Fita I, Gómez-Fernández JC.
    EMBO J; 1999 Nov 15; 18(22):6329-38. PubMed ID: 10562545
    [Abstract] [Full Text] [Related]

  • 6. Mutagenesis of the C2 domain of protein kinase C-alpha. Differential roles of Ca2+ ligands and membrane binding residues.
    Medkova M, Cho W.
    J Biol Chem; 1998 Jul 10; 273(28):17544-52. PubMed ID: 9651347
    [Abstract] [Full Text] [Related]

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  • 8. Roles of ionic residues of the C1 domain in protein kinase C-alpha activation and the origin of phosphatidylserine specificity.
    Bittova L, Stahelin RV, Cho W.
    J Biol Chem; 2001 Feb 09; 276(6):4218-26. PubMed ID: 11029472
    [Abstract] [Full Text] [Related]

  • 9. A putative phosphatidylserine binding motif is not involved in the lipid regulation of protein kinase C.
    Johnson JE, Edwards AS, Newton AC.
    J Biol Chem; 1997 Dec 05; 272(49):30787-92. PubMed ID: 9388219
    [Abstract] [Full Text] [Related]

  • 10. The C2 domain of protein kinase calpha is directly involved in the diacylglycerol-dependent binding of the C1 domain to the membrane.
    Conesa-Zamora P, Gómez-Fernández JC, Corbalán-García S.
    Biochim Biophys Acta; 2000 Sep 27; 1487(2-3):246-54. PubMed ID: 11018476
    [Abstract] [Full Text] [Related]

  • 11. Membrane binding kinetics of protein kinase C betaII mediated by the C2 domain.
    Nalefski EA, Newton AC.
    Biochemistry; 2001 Nov 06; 40(44):13216-29. PubMed ID: 11683630
    [Abstract] [Full Text] [Related]

  • 12. Interplay of C1 and C2 domains of protein kinase C-alpha in its membrane binding and activation.
    Medkova M, Cho W.
    J Biol Chem; 1999 Jul 09; 274(28):19852-61. PubMed ID: 10391930
    [Abstract] [Full Text] [Related]

  • 13. The C1 and C2 domains of protein kinase C are independent membrane targeting modules, with specificity for phosphatidylserine conferred by the C1 domain.
    Johnson JE, Giorgione J, Newton AC.
    Biochemistry; 2000 Sep 19; 39(37):11360-9. PubMed ID: 10985781
    [Abstract] [Full Text] [Related]

  • 14. Role of the Ca2+/phosphatidylserine binding region of the C2 domain in the translocation of protein kinase Calpha to the plasma membrane.
    Bolsover SR, Gomez-Fernandez JC, Corbalan-Garcia S.
    J Biol Chem; 2003 Mar 21; 278(12):10282-90. PubMed ID: 12525479
    [Abstract] [Full Text] [Related]

  • 15. C2 domains of protein kinase C isoforms alpha, beta, and gamma: activation parameters and calcium stoichiometries of the membrane-bound state.
    Kohout SC, Corbalán-García S, Torrecillas A, Goméz-Fernandéz JC, Falke JJ.
    Biochemistry; 2002 Sep 24; 41(38):11411-24. PubMed ID: 12234184
    [Abstract] [Full Text] [Related]

  • 16. Characterization of the membrane binding mode of the C2 domain of PKC epsilon.
    Corbalán-Garcia S, Sánchez-Carrillo S, García-García J, Gómez-Fernández JC.
    Biochemistry; 2003 Oct 14; 42(40):11661-8. PubMed ID: 14529276
    [Abstract] [Full Text] [Related]

  • 17. Mechanism of diacylglycerol-induced membrane targeting and activation of protein kinase Cdelta.
    Stahelin RV, Digman MA, Medkova M, Ananthanarayanan B, Rafter JD, Melowic HR, Cho W.
    J Biol Chem; 2004 Jul 09; 279(28):29501-12. PubMed ID: 15105418
    [Abstract] [Full Text] [Related]

  • 18. Electrostatic and hydrophobic interactions differentially tune membrane binding kinetics of the C2 domain of protein kinase Cα.
    Scott AM, Antal CE, Newton AC.
    J Biol Chem; 2013 Jun 07; 288(23):16905-16915. PubMed ID: 23589289
    [Abstract] [Full Text] [Related]

  • 19. Identification of acidic amino acid residues in the protein kinase C alpha V5 domain that contribute to its insensitivity to diacylglycerol.
    Stensman H, Larsson C.
    J Biol Chem; 2007 Sep 28; 282(39):28627-28638. PubMed ID: 17673466
    [Abstract] [Full Text] [Related]

  • 20. C2 domain of protein kinase C alpha: elucidation of the membrane docking surface by site-directed fluorescence and spin labeling.
    Kohout SC, Corbalán-García S, Gómez-Fernández JC, Falke JJ.
    Biochemistry; 2003 Feb 11; 42(5):1254-65. PubMed ID: 12564928
    [Abstract] [Full Text] [Related]

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