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292 related items for PubMed ID: 11708215

  • 1. Measurements of hydrogen peroxide induced premature senescence: senescence-associated beta-galactosidase and DNA synthesis index in human diploid fibroblasts with down-regulated p53 or Rb.
    Chen QM, Tu VC, Liu J.
    Biogerontology; 2000; 1(4):335-9. PubMed ID: 11708215
    [Abstract] [Full Text] [Related]

  • 2. Down regulation of p53 with HPV E6 delays and modifies cell death in oxidant response of human diploid fibroblasts: an apoptosis-like cell death associated with mitosis.
    Chen QM, Merrett JB, Dilley T, Purdom S.
    Oncogene; 2002 Aug 08; 21(34):5313-24. PubMed ID: 12149652
    [Abstract] [Full Text] [Related]

  • 3. Molecular analysis of H2O2-induced senescent-like growth arrest in normal human fibroblasts: p53 and Rb control G1 arrest but not cell replication.
    Chen QM, Bartholomew JC, Campisi J, Acosta M, Reagan JD, Ames BN.
    Biochem J; 1998 May 15; 332 ( Pt 1)(Pt 1):43-50. PubMed ID: 9576849
    [Abstract] [Full Text] [Related]

  • 4. Cell cycle regulation in H(2)O(2)-induced premature senescence of human diploid fibroblasts and regulatory control exerted by the papilloma virus E6 and E7 proteins.
    Frippiat C, Chen QM, Remacle J, Toussaint O.
    Exp Gerontol; 2000 Sep 15; 35(6-7):733-45. PubMed ID: 11053664
    [Abstract] [Full Text] [Related]

  • 5. Involvement of Rb family proteins, focal adhesion proteins and protein synthesis in senescent morphogenesis induced by hydrogen peroxide.
    Chen QM, Tu VC, Catania J, Burton M, Toussaint O, Dilley T.
    J Cell Sci; 2000 Nov 15; 113 ( Pt 22)():4087-97. PubMed ID: 11058095
    [Abstract] [Full Text] [Related]

  • 6. Inhibition of phosphatidylinostol 3-kinase uncouples H2O2-induced senescent phenotype and cell cycle arrest in normal human diploid fibroblasts.
    Wang Y, Meng A, Zhou D.
    Exp Cell Res; 2004 Aug 01; 298(1):188-96. PubMed ID: 15242773
    [Abstract] [Full Text] [Related]

  • 7. Replicative senescence and oxidant-induced premature senescence. Beyond the control of cell cycle checkpoints.
    Chen QM.
    Ann N Y Acad Sci; 2000 Jun 01; 908():111-25. PubMed ID: 10911952
    [Abstract] [Full Text] [Related]

  • 8. Apoptosis or senescence-like growth arrest: influence of cell-cycle position, p53, p21 and bax in H2O2 response of normal human fibroblasts.
    Chen QM, Liu J, Merrett JB.
    Biochem J; 2000 Apr 15; 347(Pt 2):543-51. PubMed ID: 10749685
    [Abstract] [Full Text] [Related]

  • 9. Down-regulation and decreased activity of cyclin-dependent kinase 2 in H2O2-induced premature senescence.
    Frippiat C, Remacle J, Toussaint O.
    Int J Biochem Cell Biol; 2003 Feb 15; 35(2):246-54. PubMed ID: 12479875
    [Abstract] [Full Text] [Related]

  • 10. Subcytotoxic H2O2 stress triggers a release of transforming growth factor-beta 1, which induces biomarkers of cellular senescence of human diploid fibroblasts.
    Frippiat C, Chen QM, Zdanov S, Magalhaes JP, Remacle J, Toussaint O.
    J Biol Chem; 2001 Jan 26; 276(4):2531-7. PubMed ID: 11060295
    [Abstract] [Full Text] [Related]

  • 11. Expression of human telomerase (hTERT) does not prevent stress-induced senescence in normal human fibroblasts but protects the cells from stress-induced apoptosis and necrosis.
    Gorbunova V, Seluanov A, Pereira-Smith OM.
    J Biol Chem; 2002 Oct 11; 277(41):38540-9. PubMed ID: 12140282
    [Abstract] [Full Text] [Related]

  • 12. Transition to an irreversible state of senescence in HeLa cells arrested by repression of HPV E6 and E7 genes.
    Kang HT, Lee CJ, Seo EJ, Bahn YJ, Kim HJ, Hwang ES.
    Mech Ageing Dev; 2004 Jan 11; 125(1):31-40. PubMed ID: 14706235
    [Abstract] [Full Text] [Related]

  • 13. Senescence-associated beta-galactosidase is lysosomal beta-galactosidase.
    Lee BY, Han JA, Im JS, Morrone A, Johung K, Goodwin EC, Kleijer WJ, DiMaio D, Hwang ES.
    Aging Cell; 2006 Apr 11; 5(2):187-95. PubMed ID: 16626397
    [Abstract] [Full Text] [Related]

  • 14. Human papillomavirus oncoprotein E7 targets the promyelocytic leukemia protein and circumvents cellular senescence via the Rb and p53 tumor suppressor pathways.
    Bischof O, Nacerddine K, Dejean A.
    Mol Cell Biol; 2005 Feb 11; 25(3):1013-24. PubMed ID: 15657429
    [Abstract] [Full Text] [Related]

  • 15. Induction of senescence-like state and suppression of telomerase activity through inhibition of HPV E6/E7 gene expression in cells immortalized by HPV16 DNA.
    Lee CJ, Suh EJ, Kang HT, Im JS, Um SJ, Park JS, Hwang ES.
    Exp Cell Res; 2002 Jul 15; 277(2):173-82. PubMed ID: 12083799
    [Abstract] [Full Text] [Related]

  • 16. Methods to detect biomarkers of cellular senescence: the senescence-associated beta-galactosidase assay.
    Itahana K, Campisi J, Dimri GP.
    Methods Mol Biol; 2007 Jul 15; 371():21-31. PubMed ID: 17634571
    [Abstract] [Full Text] [Related]

  • 17. No increase in senescence-associated beta-galactosidase activity in Werner syndrome fibroblasts after exposure to H2O2.
    de Magalhães JP, Migeot V, Mainfroid V, de Longueville F, Remacle J, Toussaint O.
    Ann N Y Acad Sci; 2004 Jun 15; 1019():375-8. PubMed ID: 15247048
    [Abstract] [Full Text] [Related]

  • 18. Role of the retinoblastoma pathway in senescence triggered by repression of the human papillomavirus E7 protein in cervical carcinoma cells.
    Psyrri A, DeFilippis RA, Edwards AP, Yates KE, Manuelidis L, DiMaio D.
    Cancer Res; 2004 May 01; 64(9):3079-86. PubMed ID: 15126344
    [Abstract] [Full Text] [Related]

  • 19. Human fibroblasts require the Rb family of tumor suppressors, but not p53, for PML-induced senescence.
    Mallette FA, Goumard S, Gaumont-Leclerc MF, Moiseeva O, Ferbeyre G.
    Oncogene; 2004 Jan 08; 23(1):91-9. PubMed ID: 14712214
    [Abstract] [Full Text] [Related]

  • 20. Knocking down p53 with siRNA does not affect the overexpression of p21WAF-1 after exposure of IMR-90 hTERT fibroblasts to a sublethal concentration of H2O2 leading to premature senescence.
    Zdanov S, Debacq-Chainiaux F, Toussaint O.
    Ann N Y Acad Sci; 2007 Apr 08; 1100():316-22. PubMed ID: 17460194
    [Abstract] [Full Text] [Related]

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