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290 related items for PubMed ID: 11709086

  • 1. Antagonism of PI 3-kinase-dependent signalling pathways by the tumour suppressor protein, PTEN.
    Downes CP, Bennett D, McConnachie G, Leslie NR, Pass I, MacPhee C, Patel L, Gray A.
    Biochem Soc Trans; 2001 Nov; 29(Pt 6):846-51. PubMed ID: 11709086
    [Abstract] [Full Text] [Related]

  • 2. PTEN: The down side of PI 3-kinase signalling.
    Leslie NR, Downes CP.
    Cell Signal; 2002 Apr; 14(4):285-95. PubMed ID: 11858936
    [Abstract] [Full Text] [Related]

  • 3. Evidence that SHIP-1 contributes to phosphatidylinositol 3,4,5-trisphosphate metabolism in T lymphocytes and can regulate novel phosphoinositide 3-kinase effectors.
    Freeburn RW, Wright KL, Burgess SJ, Astoul E, Cantrell DA, Ward SG.
    J Immunol; 2002 Nov 15; 169(10):5441-50. PubMed ID: 12421919
    [Abstract] [Full Text] [Related]

  • 4. Targeting mutants of PTEN reveal distinct subsets of tumour suppressor functions.
    Leslie NR, Bennett D, Gray A, Pass I, Hoang-Xuan K, Downes CP.
    Biochem J; 2001 Jul 15; 357(Pt 2):427-35. PubMed ID: 11439092
    [Abstract] [Full Text] [Related]

  • 5. Interfacial kinetic analysis of the tumour suppressor phosphatase, PTEN: evidence for activation by anionic phospholipids.
    McConnachie G, Pass I, Walker SM, Downes CP.
    Biochem J; 2003 May 01; 371(Pt 3):947-55. PubMed ID: 12534371
    [Abstract] [Full Text] [Related]

  • 6. Acute regulation of the tumour suppressor phosphatase, PTEN, by anionic lipids and reactive oxygen species.
    Downes CP, Walker S, McConnachie G, Lindsay Y, Batty IH, Leslie NR.
    Biochem Soc Trans; 2004 Apr 01; 32(Pt 2):338-42. PubMed ID: 15046604
    [Abstract] [Full Text] [Related]

  • 7. PTEN, but not SHIP2, suppresses insulin signaling through the phosphatidylinositol 3-kinase/Akt pathway in 3T3-L1 adipocytes.
    Tang X, Powelka AM, Soriano NA, Czech MP, Guilherme A.
    J Biol Chem; 2005 Jun 10; 280(23):22523-9. PubMed ID: 15824124
    [Abstract] [Full Text] [Related]

  • 8. Allosteric activation of PTEN phosphatase by phosphatidylinositol 4,5-bisphosphate.
    Campbell RB, Liu F, Ross AH.
    J Biol Chem; 2003 Sep 05; 278(36):33617-20. PubMed ID: 12857747
    [Abstract] [Full Text] [Related]

  • 9. The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate.
    Maehama T, Dixon JE.
    J Biol Chem; 1998 May 29; 273(22):13375-8. PubMed ID: 9593664
    [Abstract] [Full Text] [Related]

  • 10. The tumour-suppressor function of PTEN requires an N-terminal lipid-binding motif.
    Walker SM, Leslie NR, Perera NM, Batty IH, Downes CP.
    Biochem J; 2004 Apr 15; 379(Pt 2):301-7. PubMed ID: 14711368
    [Abstract] [Full Text] [Related]

  • 11. Regulation of the PTEN phosphatase.
    Gericke A, Munson M, Ross AH.
    Gene; 2006 Jun 07; 374():1-9. PubMed ID: 16675164
    [Abstract] [Full Text] [Related]

  • 12. The complexity of PTEN: mutation, marker and potential target for therapeutic intervention.
    Steelman LS, Bertrand FE, McCubrey JA.
    Expert Opin Ther Targets; 2004 Dec 07; 8(6):537-50. PubMed ID: 15584861
    [Abstract] [Full Text] [Related]

  • 13. PTEN and myotubularin phosphatases: from 3-phosphoinositide dephosphorylation to disease.
    Wishart MJ, Dixon JE.
    Trends Cell Biol; 2002 Dec 07; 12(12):579-85. PubMed ID: 12495846
    [Abstract] [Full Text] [Related]

  • 14. Analysis of the cellular functions of PTEN using catalytic domain and C-terminal mutations: differential effects of C-terminal deletion on signalling pathways downstream of phosphoinositide 3-kinase.
    Leslie NR, Gray A, Pass I, Orchiston EA, Downes CP.
    Biochem J; 2000 Mar 15; 346 Pt 3(Pt 3):827-33. PubMed ID: 10698713
    [Abstract] [Full Text] [Related]

  • 15. Src family protein-tyrosine kinases alter the function of PTEN to regulate phosphatidylinositol 3-kinase/AKT cascades.
    Lu Y, Yu Q, Liu JH, Zhang J, Wang H, Koul D, McMurray JS, Fang X, Yung WK, Siminovitch KA, Mills GB.
    J Biol Chem; 2003 Oct 10; 278(41):40057-66. PubMed ID: 12869565
    [Abstract] [Full Text] [Related]

  • 16. Metabolic switching of PI3K-dependent lipid signals.
    Downes CP, Leslie NR, Batty IH, van der Kaay J.
    Biochem Soc Trans; 2007 Apr 10; 35(Pt 2):188-92. PubMed ID: 17371235
    [Abstract] [Full Text] [Related]

  • 17. Pten signaling in gliomas.
    Knobbe CB, Merlo A, Reifenberger G.
    Neuro Oncol; 2002 Jul 10; 4(3):196-211. PubMed ID: 12084351
    [Abstract] [Full Text] [Related]

  • 18. Regulation of phosphoinositide metabolism, Akt phosphorylation, and glucose transport by PTEN (phosphatase and tensin homolog deleted on chromosome 10) in 3T3-L1 adipocytes.
    Ono H, Katagiri H, Funaki M, Anai M, Inukai K, Fukushima Y, Sakoda H, Ogihara T, Onishi Y, Fujishiro M, Kikuchi M, Oka Y, Asano T.
    Mol Endocrinol; 2001 Aug 10; 15(8):1411-22. PubMed ID: 11463863
    [Abstract] [Full Text] [Related]

  • 19. PTEN: life as a tumor suppressor.
    Simpson L, Parsons R.
    Exp Cell Res; 2001 Mar 10; 264(1):29-41. PubMed ID: 11237521
    [Abstract] [Full Text] [Related]

  • 20. Regulation of cell migration by the C2 domain of the tumor suppressor PTEN.
    Raftopoulou M, Etienne-Manneville S, Self A, Nicholls S, Hall A.
    Science; 2004 Feb 20; 303(5661):1179-81. PubMed ID: 14976311
    [Abstract] [Full Text] [Related]

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