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226 related items for PubMed ID: 1170938

  • 1. Effect of methotrexate on thymidylate synthetase in cultured parenchymal cells isolated from regenerating rat liver.
    Bonney RJ, Maley F.
    Cancer Res; 1975 Aug; 35(8):1950-6. PubMed ID: 1170938
    [Abstract] [Full Text] [Related]

  • 2. Elevation of dihydrofolate reductase, thymidylate synthetase, and thymidine kinase in cultured mammalian cells after exposure to folate antagonists.
    Chello PL, McQueen CA, DeAngelis LM, Bertino JR.
    Cancer Res; 1976 Jul; 36(7 PT 1):2442-9. PubMed ID: 1277151
    [Abstract] [Full Text] [Related]

  • 3. Thymidylate synthetase activity in the Novikoff hepatoma.
    Roth JJ, Roth JS.
    Cancer Res; 1976 Dec; 36(12):4500-3. PubMed ID: 187325
    [Abstract] [Full Text] [Related]

  • 4. Thymidylate synthetase and dihydrofolic acid reductase in the stimulated human lymphocyte.
    Haurani FI, Kardinal CG, Biermann WA.
    J Cell Physiol; 1978 Apr; 95(1):49-55. PubMed ID: 147880
    [Abstract] [Full Text] [Related]

  • 5. Biochemical studies on PT523, a potent nonpolyglutamatable antifolate, in cultured cells.
    Rhee MS, Galivan J, Wright JE, Rosowsky A.
    Mol Pharmacol; 1994 Apr; 45(4):783-91. PubMed ID: 7514264
    [Abstract] [Full Text] [Related]

  • 6. Interaction of thymidylate synthetase and dihydrofolate reductase enzymes in vitro and in vivo.
    Kawai M, Hillcoat BL.
    Cancer Res; 1974 Jul; 34(7):1619-26. PubMed ID: 4833915
    [No Abstract] [Full Text] [Related]

  • 7. Thymidylate synthetase levels as a factor in 5-fluorodeoxyuridine and methotrexate cytotoxicity in gastrointestinal tumor cells.
    Washtien WL.
    Mol Pharmacol; 1982 May; 21(3):723-8. PubMed ID: 6213845
    [Abstract] [Full Text] [Related]

  • 8. Biochemical and pharmacologic rationale for high-dose methotrexate.
    Jolivet J.
    NCI Monogr; 1987 May; (5):61-5. PubMed ID: 2448656
    [Abstract] [Full Text] [Related]

  • 9. The role of methotrexate and dihydrofolate polyglutamates in the enhancement of fluorouracil action by methotrexate.
    Fernandes DJ, Moroson BA, Bertino JR.
    Cancer Treat Rep; 1981 May; 65 Suppl 1():29-35. PubMed ID: 6173121
    [Abstract] [Full Text] [Related]

  • 10. Biochemical and biological studies on 2-desamino-2-methylaminopterin, an antifolate the polyglutamates of which are more potent than the monoglutamate against three key enzymes of folate metabolism.
    Rosowsky A, Galivan J, Beardsley GP, Bader H, O'Connor BM, Russello O, Moroson BA, DeYarman MT, Kerwar SS, Freisheim JH.
    Cancer Res; 1992 Apr 15; 52(8):2148-55. PubMed ID: 1313737
    [Abstract] [Full Text] [Related]

  • 11. A comparison of dihydrofolate reductase activity in intact leukemia cells and squamous cell carcinoma.
    FitzGerald GB, Wick MM.
    Anticancer Drug Des; 1989 Jun 15; 4(1):79-87. PubMed ID: 2757754
    [Abstract] [Full Text] [Related]

  • 12. Impact of polyglutamation on sensitivity to raltitrexed and methotrexate in relation to drug-induced inhibition of de novo thymidylate and purine biosynthesis in CCRF-CEM cell lines.
    Barnes MJ, Estlin EJ, Taylor GA, Aherne GW, Hardcastle A, McGuire JJ, Calvete JA, Lunec J, Pearson AD, Newell DR.
    Clin Cancer Res; 1999 Sep 15; 5(9):2548-58. PubMed ID: 10499632
    [Abstract] [Full Text] [Related]

  • 13. Immunosuppressive properties of methotrexate: apoptosis and clonal deletion of activated peripheral T cells.
    Genestier L, Paillot R, Fournel S, Ferraro C, Miossec P, Revillard JP.
    J Clin Invest; 1998 Jul 15; 102(2):322-8. PubMed ID: 9664073
    [Abstract] [Full Text] [Related]

  • 14. Resistance to methotrexate in thymidylate synthetase-deficient mutants of cultured mouse mammary tumor FM3A cells.
    Ayusawa D, Koyama H, Seno T.
    Cancer Res; 1981 Apr 15; 41(4):1497-501. PubMed ID: 6452198
    [Abstract] [Full Text] [Related]

  • 15. In vitro and in vivo antitumor activity of methotrexate conjugated to human serum albumin in human cancer cells.
    Wosikowski K, Biedermann E, Rattel B, Breiter N, Jank P, Löser R, Jansen G, Peters GJ.
    Clin Cancer Res; 2003 May 15; 9(5):1917-26. PubMed ID: 12738750
    [Abstract] [Full Text] [Related]

  • 16. Inhibition of thymidylate synthetase of the human lymphocytes.
    Haurani FI.
    Cancer Biochem Biophys; 1979 May 15; 4(2):75-7. PubMed ID: 317899
    [Abstract] [Full Text] [Related]

  • 17. Relative activities of thymidylate synthetase and thymidine kinase in rat tissues.
    Herzfeld A, Raper SM.
    Cancer Res; 1980 Mar 15; 40(3):744-50. PubMed ID: 7471094
    [Abstract] [Full Text] [Related]

  • 18. Role of thymidine kinase and thymidylate synthetase in the cytostatic, antimetabolic, and antitumor effects of the carbocyclic analogue of 5-nitro-2'-deoxyuridine. A comparison with 5-nitro-2'-deoxyuridine.
    Balzarini J, De Clercq E, Herdewijn P, Robins MJ.
    Mol Pharmacol; 1985 May 15; 27(5):578-83. PubMed ID: 3990680
    [Abstract] [Full Text] [Related]

  • 19. Methotrexate cytotoxicity in cultured human leukemic cells studied by flow cytometry.
    Taylor IW, Tattersall MH.
    Cancer Res; 1981 Apr 15; 41(4):1549-58. PubMed ID: 6163527
    [Abstract] [Full Text] [Related]

  • 20. Thymidylate synthase as a target for growth inhibition in methotrexate-sensitive and -resistant human head and neck cancer and leukemia cell lines.
    McGuire JJ, Magee KJ, Russell CA, Canestrari JM.
    Oncol Res; 1997 Apr 15; 9(3):139-47. PubMed ID: 9220499
    [Abstract] [Full Text] [Related]

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