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170 related items for PubMed ID: 11724351

  • 1. Doxorubicin-formaldehyde conjugate, doxoform: induction of apoptosis relative to doxorubicin.
    Burke PJ, Koch TH.
    Anticancer Res; 2001; 21(4A):2753-60. PubMed ID: 11724351
    [Abstract] [Full Text] [Related]

  • 2. Nuclear targeting and nuclear retention of anthracycline-formaldehyde conjugates implicates DNA covalent bonding in the cytotoxic mechanism of anthracyclines.
    Taatjes DJ, Fenick DJ, Koch TH.
    Chem Res Toxicol; 1999 Jul; 12(7):588-96. PubMed ID: 10409398
    [Abstract] [Full Text] [Related]

  • 3. Growth inhibition, nuclear uptake, and retention of anthracycline-formaldehyde conjugates in prostate cancer cells relative to clinical anthracyclines.
    Taatjes DJ, Koch TH.
    Anticancer Res; 1999 Jul; 19(2A):1201-8. PubMed ID: 10368676
    [Abstract] [Full Text] [Related]

  • 4. A P-glycoprotein- and MRP1-independent doxorubicin-resistant variant of the MCF-7 breast cancer cell line with defects in caspase-6, -7, -8, -9 and -10 activation pathways.
    Park SJ, Wu CH, Safa AR.
    Anticancer Res; 2004 Jul; 24(1):123-31. PubMed ID: 15015586
    [Abstract] [Full Text] [Related]

  • 5. CPI-0004Na, a new extracellularly tumor-activated prodrug of doxorubicin: in vivo toxicity, activity, and tissue distribution confirm tumor cell selectivity.
    Dubois V, Dasnois L, Lebtahi K, Collot F, Heylen N, Havaux N, Fernandez AM, Lobl TJ, Oliyai C, Nieder M, Shochat D, Yarranton GT, Trouet A.
    Cancer Res; 2002 Apr 15; 62(8):2327-31. PubMed ID: 11956091
    [Abstract] [Full Text] [Related]

  • 6. Apoptosis induced by anthracycline antibiotics in P388 parent and multidrug-resistant cells.
    Ling YH, Priebe W, Perez-Soler R.
    Cancer Res; 1993 Apr 15; 53(8):1845-52. PubMed ID: 8467504
    [Abstract] [Full Text] [Related]

  • 7. Antiestrogen binding site and estrogen receptor mediate uptake and distribution of 4-hydroxytamoxifen-targeted doxorubicin-formaldehyde conjugate in breast cancer cells.
    Burke PJ, Kalet BT, Koch TH.
    J Med Chem; 2004 Dec 16; 47(26):6509-18. PubMed ID: 15588086
    [Abstract] [Full Text] [Related]

  • 8. Ultrasmall gold-doxorubicin conjugates rapidly kill apoptosis-resistant cancer cells.
    Zhang X, Chibli H, Mielke R, Nadeau J.
    Bioconjug Chem; 2011 Feb 16; 22(2):235-43. PubMed ID: 21189001
    [Abstract] [Full Text] [Related]

  • 9. Sigma-2 receptor agonists activate a novel apoptotic pathway and potentiate antineoplastic drugs in breast tumor cell lines.
    Crawford KW, Bowen WD.
    Cancer Res; 2002 Jan 01; 62(1):313-22. PubMed ID: 11782394
    [Abstract] [Full Text] [Related]

  • 10. Evaluation of apoptosis induced in vitro by cladribine (2-CdA) combined with anthracyclines in lymphocytes from patients with B-cell chronic lymphocytic leukemia.
    Szmigielska-Kaplon A, Smolewski P, Najder M, Robak T.
    Ann Hematol; 2002 Sep 01; 81(9):508-13. PubMed ID: 12373351
    [Abstract] [Full Text] [Related]

  • 11. Bcl-2 and mdr-1 gene expression during doxorubicin-induced apoptosis in murine leukemic P388 and P388/R84 cells.
    Ramachandran C, You W, Krishan A.
    Anticancer Res; 1997 Sep 01; 17(5A):3369-76. PubMed ID: 9413174
    [Abstract] [Full Text] [Related]

  • 12. Antitumor activity of a phenoxazine compound, 2-amino-4,4alpha-dihydro-4alpha,7-dimethyl-3H-phenoxazine-3-one against human B cell and T cell lymphoblastoid cell lines: induction of mixed types of cell death, apoptosis, and necrosis.
    Koshibu-Koizumi J, Akazawa M, Iwamoto T, Takasaki M, Mizuno F, Kobayashi R, Abe A, Tomoda A, Hamatake M, Ishida R.
    J Cancer Res Clin Oncol; 2002 Jul 01; 128(7):363-8. PubMed ID: 12136250
    [Abstract] [Full Text] [Related]

  • 13. Design, synthesis, and biological evaluation of doxorubicin-formaldehyde conjugates targeted to breast cancer cells.
    Burke PJ, Koch TH.
    J Med Chem; 2004 Feb 26; 47(5):1193-206. PubMed ID: 14971899
    [Abstract] [Full Text] [Related]

  • 14. Induction of apoptosis in human T-cells by organomercuric compounds: a flow cytometric analysis.
    Shenker BJ, Datar S, Mansfield K, Shapiro IM.
    Toxicol Appl Pharmacol; 1997 Apr 26; 143(2):397-406. PubMed ID: 9144456
    [Abstract] [Full Text] [Related]

  • 15. The effect of doxorubicin on MEK-ERK signaling predicts its efficacy in HCC.
    Choi J, Yip-Schneider M, Albertin F, Wiesenauer C, Wang Y, Schmidt CM.
    J Surg Res; 2008 Dec 26; 150(2):219-26. PubMed ID: 18468633
    [Abstract] [Full Text] [Related]

  • 16. Epidoxoform: a hydrolytically more stable anthracycline-formaldehyde conjugate toxic to resistant tumor cells.
    Taatjes DJ, Fenick DJ, Koch TH.
    J Med Chem; 1998 Apr 09; 41(8):1306-14. PubMed ID: 9548820
    [Abstract] [Full Text] [Related]

  • 17. Doxorubicin-induced death in neuroblastoma does not involve death receptors in S-type cells and is caspase-independent in N-type cells.
    Hopkins-Donaldson S, Yan P, Bourloud KB, Muhlethaler A, Bodmer JL, Gross N.
    Oncogene; 2002 Sep 05; 21(39):6132-7. PubMed ID: 12203125
    [Abstract] [Full Text] [Related]

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  • 20. Proteinase-3, a serine protease which mediates doxorubicin-induced apoptosis in the HL-60 leukemia cell line, is downregulated in its doxorubicin-resistant variant.
    Wu CH, Gordon J, Rastegar M, Ogretmen B, Safa AR.
    Oncogene; 2002 Aug 01; 21(33):5160-74. PubMed ID: 12140766
    [Abstract] [Full Text] [Related]

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