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Journal Abstract Search


229 related items for PubMed ID: 11729359

  • 1. Molecular and pharmacokinetic evaluation of rat hepatic and gastrointestinal cytochrome p450 induction by tamoxifen.
    Cotreau MM, von Moltke LL, Harmatz JS, Greenblatt DJ.
    Pharmacology; 2001; 63(4):210-9. PubMed ID: 11729359
    [Abstract] [Full Text] [Related]

  • 2. Methodologies to study the induction of rat hepatic and intestinal cytochrome P450 3A at the mRNA, protein, and catalytic activity level.
    Cotreau MM, von Moltke LL, Beinfeld MC, Greenblatt DJ.
    J Pharmacol Toxicol Methods; 2000; 43(1):41-54. PubMed ID: 11091129
    [Abstract] [Full Text] [Related]

  • 3. The aromatase inactivator 4-hydroxyandrostenedione (4-OH-A) inhibits tamoxifen metabolism by rat hepatic cytochrome P-450 3A: potential for drug-drug interaction of tamoxifen and 4-OH-A in combined anti-breast cancer therapy.
    Dehal SS, Brodie AM, Kupfer D.
    Drug Metab Dispos; 1999 Mar; 27(3):389-94. PubMed ID: 10064571
    [Abstract] [Full Text] [Related]

  • 4. Midazolam is a phenobarbital-like cytochrome p450 inducer in rats.
    Hoen PA, Bijsterbosch MK, van Berkel TJ, Vermeulen NP, Commandeur JN.
    J Pharmacol Exp Ther; 2001 Dec; 299(3):921-7. PubMed ID: 11714877
    [Abstract] [Full Text] [Related]

  • 5. In-vivo and in-vitro metabolic clearance of midazolam, a cytochrome P450 3A substrate, by the liver under normal and increased enzyme activity in rats.
    Higashikawa F, Murakami T, Kaneda T, Takano M.
    J Pharm Pharmacol; 1999 Apr; 51(4):405-10. PubMed ID: 10385212
    [Abstract] [Full Text] [Related]

  • 6. Rapid determination of rat hepatocyte mRNA induction potential using oligonucleotide probes for CYP1A1, 1A2, 3A and 4A1.
    Surry DD, Meneses-Lorente G, Heavens R, Jack A, Evans DC.
    Xenobiotica; 2000 May; 30(5):441-56. PubMed ID: 10875679
    [Abstract] [Full Text] [Related]

  • 7. Effect of dexamethasone on the intestinal first-pass metabolism of indinavir in rats: evidence of cytochrome P-450 3A [correction of P-450 A] and p-glycoprotein induction .
    Lin JH, Chiba M, Chen IW, Nishime JA, deLuna FA, Yamazaki M, Lin YJ.
    Drug Metab Dispos; 1999 Oct; 27(10):1187-93. PubMed ID: 10497146
    [Abstract] [Full Text] [Related]

  • 8. Induction of liver cytochrome P-450 (CYP) 3A in male and female rats by a steroidal androgen receptor antagonist, zanoterone.
    Roberts AE, Ritz MA, Hoekstra S, Descotes G, Hincks JR.
    J Biochem Toxicol; 1996 Oct; 11(3):101-10. PubMed ID: 9029268
    [Abstract] [Full Text] [Related]

  • 9. Cytochrome P-450 3A and 2D6 catalyze ortho hydroxylation of 4-hydroxytamoxifen and 3-hydroxytamoxifen (droloxifene) yielding tamoxifen catechol: involvement of catechols in covalent binding to hepatic proteins.
    Dehal SS, Kupfer D.
    Drug Metab Dispos; 1999 Jun; 27(6):681-8. PubMed ID: 10348797
    [Abstract] [Full Text] [Related]

  • 10. CAR and PXR expression and inducibility of CYP2B and CYP3A activities in rat and rabbit lungs.
    Chirulli V, Longo V, Marini S, Mazzaccaro A, Fiorio R, Gervasi PG.
    Life Sci; 2005 Apr 15; 76(22):2535-46. PubMed ID: 15769478
    [Abstract] [Full Text] [Related]

  • 11. Reversible and irreversible inhibition of CYP3A enzymes by tamoxifen and metabolites.
    Zhao XJ, Jones DR, Wang YH, Grimm SW, Hall SD.
    Xenobiotica; 2002 Oct 15; 32(10):863-78. PubMed ID: 12419016
    [Abstract] [Full Text] [Related]

  • 12. Modulation of hepatic CYP2A1, CYP2C11, and CYP3A9 expression in adult rats by neonatal administration of tamoxifen.
    Kawai M, Bandiera SM, Chang TK, Poulet FM, Vancutsem PM, Bellward GD.
    Drug Metab Dispos; 1999 Dec 15; 27(12):1392-8. PubMed ID: 10570019
    [Abstract] [Full Text] [Related]

  • 13. The effect of age, sex, and rifampin administration on intestinal and hepatic cytochrome P450 3A activity.
    Gorski JC, Vannaprasaht S, Hamman MA, Ambrosius WT, Bruce MA, Haehner-Daniels B, Hall SD.
    Clin Pharmacol Ther; 2003 Sep 15; 74(3):275-87. PubMed ID: 12966371
    [Abstract] [Full Text] [Related]

  • 14. Pharmacokinetic interaction of cytochrome P450 3A-related compounds with rhodamine 123, a P-glycoprotein substrate, in rats pretreated with dexamethasone.
    Yumoto R, Murakami T, Sanemasa M, Nasu R, Nagai J, Takano M.
    Drug Metab Dispos; 2001 Feb 15; 29(2):145-51. PubMed ID: 11159804
    [Abstract] [Full Text] [Related]

  • 15. Association of cytochrome P450 induction with oxidative stress in vivo as evidenced by 3-hydroxylation of salicylate.
    Strolin-Benedetti M, Brogin G, Bani M, Oesch F, Hengstler JG.
    Xenobiotica; 1999 Nov 15; 29(11):1171-80. PubMed ID: 10598750
    [Abstract] [Full Text] [Related]

  • 16. Application of semisimultaneous midazolam administration for hepatic and intestinal cytochrome P450 3A phenotyping.
    Lee JI, Chaves-Gnecco D, Amico JA, Kroboth PD, Wilson JW, Frye RF.
    Clin Pharmacol Ther; 2002 Dec 15; 72(6):718-28. PubMed ID: 12496753
    [Abstract] [Full Text] [Related]

  • 17. Reduction in tamoxifen-induced CYP3A2 expression and DNA adducts using antisense technology.
    Mahadevan B, Arora V, Schild LJ, Keshava C, Cate ML, Iversen PL, Poirier MC, Weston A, Pereira C, Baird WM.
    Mol Carcinog; 2006 Feb 15; 45(2):118-25. PubMed ID: 16329150
    [Abstract] [Full Text] [Related]

  • 18. Intravenous and oral alfentanil as in vivo probes for hepatic and first-pass cytochrome P450 3A activity: noninvasive assessment by use of pupillary miosis.
    Kharasch ED, Walker A, Hoffer C, Sheffels P.
    Clin Pharmacol Ther; 2004 Nov 15; 76(5):452-66. PubMed ID: 15536460
    [Abstract] [Full Text] [Related]

  • 19. Unchanged cytochrome P450 3A (CYP3A) expression and metabolism of midazolam, triazolam, and dexamethasone in mdr(-/-) mouse liver microsomes.
    Perloff MD, von Moltke LL, Cotreau MM, Greenblatt DJ.
    Biochem Pharmacol; 1999 Jun 01; 57(11):1227-32. PubMed ID: 10230766
    [Abstract] [Full Text] [Related]

  • 20. Effects of age on in vitro midazolam biotransformation in male CD-1 mouse liver microsomes.
    Warrington JS, Poku JW, von Moltke LL, Shader RI, Harmatz JS, Greenblatt DJ.
    J Pharmacol Exp Ther; 2000 Mar 01; 292(3):1024-31. PubMed ID: 10688619
    [Abstract] [Full Text] [Related]


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