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140 related items for PubMed ID: 11731004

  • 1. Subcellular localization of presenilin 2 endoproteolytic C-terminal fragments.
    Tekirian TL, Merriam DE, Marshansky V, Miller J, Crowley AC, Chan H, Ausiello D, Brown D, Buxbaum JD, Xia W, Wasco W.
    Brain Res Mol Brain Res; 2001 Nov 30; 96(1-2):14-20. PubMed ID: 11731004
    [Abstract] [Full Text] [Related]

  • 2. Calsenilin is a substrate for caspase-3 that preferentially interacts with the familial Alzheimer's disease-associated C-terminal fragment of presenilin 2.
    Choi EK, Zaidi NF, Miller JS, Crowley AC, Merriam DE, Lilliehook C, Buxbaum JD, Wasco W.
    J Biol Chem; 2001 Jun 01; 276(22):19197-204. PubMed ID: 11278424
    [Abstract] [Full Text] [Related]

  • 3. Presenilin 1 regulates the processing of beta-amyloid precursor protein C-terminal fragments and the generation of amyloid beta-protein in endoplasmic reticulum and Golgi.
    Xia W, Zhang J, Ostaszewski BL, Kimberly WT, Seubert P, Koo EH, Shen J, Selkoe DJ.
    Biochemistry; 1998 Nov 24; 37(47):16465-71. PubMed ID: 9843412
    [Abstract] [Full Text] [Related]

  • 4. C-terminal maturation fragments of presenilin 1 and 2 control secretion of APP alpha and A beta by human cells and are degraded by proteasome.
    da Costa CA, Ancolio K, Checler F.
    Mol Med; 1999 Mar 24; 5(3):160-8. PubMed ID: 10404513
    [Abstract] [Full Text] [Related]

  • 5. Subcellular distribution and turnover of presenilins in transfected cells.
    Zhang J, Kang DE, Xia W, Okochi M, Mori H, Selkoe DJ, Koo EH.
    J Biol Chem; 1998 May 15; 273(20):12436-42. PubMed ID: 9575200
    [Abstract] [Full Text] [Related]

  • 6. Subcellular compartment and molecular subdomain of beta-amyloid precursor protein relevant to the Abeta 42-promoting effects of Alzheimer mutant presenilin 2.
    Iwata H, Tomita T, Maruyama K, Iwatsubo T.
    J Biol Chem; 2001 Jun 15; 276(24):21678-85. PubMed ID: 11283011
    [Abstract] [Full Text] [Related]

  • 7. The C-terminal fragment of presenilin 2 triggers p53-mediated staurosporine-induced apoptosis, a function independent of the presenilinase-derived N-terminal counterpart.
    Alves da Costa C, Mattson MP, Ancolio K, Checler F.
    J Biol Chem; 2003 Apr 04; 278(14):12064-9. PubMed ID: 12556443
    [Abstract] [Full Text] [Related]

  • 8. Alzheimer's disease-associated presenilin 1 in neuronal cells: evidence for localization to the endoplasmic reticulum-Golgi intermediate compartment.
    Culvenor JG, Maher F, Evin G, Malchiodi-Albedi F, Cappai R, Underwood JR, Davis JB, Karran EH, Roberts GW, Beyreuther K, Masters CL.
    J Neurosci Res; 1997 Sep 15; 49(6):719-31. PubMed ID: 9335259
    [Abstract] [Full Text] [Related]

  • 9. Abrogation of the presenilin 1/beta-catenin interaction and preservation of the heterodimeric presenilin 1 complex following caspase activation.
    Tesco G, Kim TW, Diehlmann A, Beyreuther K, Tanzi RE.
    J Biol Chem; 1998 Dec 18; 273(51):33909-14. PubMed ID: 9852041
    [Abstract] [Full Text] [Related]

  • 10. Evidence that intramolecular associations between presenilin domains are obligatory for endoproteolytic processing.
    Saura CA, Tomita T, Davenport F, Harris CL, Iwatsubo T, Thinakaran G.
    J Biol Chem; 1999 May 14; 274(20):13818-23. PubMed ID: 10318786
    [Abstract] [Full Text] [Related]

  • 11. Subcellular localization of presenilins: association with a unique membrane pool in cultured cells.
    Kim SH, Lah JJ, Thinakaran G, Levey A, Sisodia SS.
    Neurobiol Dis; 2000 Apr 14; 7(2):99-117. PubMed ID: 10783294
    [Abstract] [Full Text] [Related]

  • 12. Processing of wild-type and mutant familial Alzheimer's disease-associated presenilin-1 in cultured neurons.
    Weihl CC, Ghadge GD, Miller RJ, Roos RP.
    J Neurochem; 1999 Jul 14; 73(1):31-40. PubMed ID: 10386952
    [Abstract] [Full Text] [Related]

  • 13. Brain expression of presenilins in sporadic and early-onset, familial Alzheimer's disease.
    Mathews PM, Cataldo AM, Kao BH, Rudnicki AG, Qin X, Yang JL, Jiang Y, Picciano M, Hulette C, Lippa CF, Bird TD, Nochlin D, Walter J, Haass C, Lévesque L, Fraser PE, Andreadis A, Nixon RA.
    Mol Med; 2000 Oct 14; 6(10):878-91. PubMed ID: 11126202
    [Abstract] [Full Text] [Related]

  • 14. Presenilin 2 familial Alzheimer's disease mutations result in partial loss of function and dramatic changes in Abeta 42/40 ratios.
    Walker ES, Martinez M, Brunkan AL, Goate A.
    J Neurochem; 2005 Jan 14; 92(2):294-301. PubMed ID: 15663477
    [Abstract] [Full Text] [Related]

  • 15. Effects of presenilin N-terminal fragments on production of amyloid beta peptide and accumulation of endogenous presenilins.
    Shirotani K, Takahashi K, Tabira T.
    Neurosci Lett; 1999 Feb 26; 262(1):37-40. PubMed ID: 10076867
    [Abstract] [Full Text] [Related]

  • 16. Determination of a cleavage site of presenilin 2 protein in stably transfected SH-SY5Y human neuroblastoma cell lines.
    Shirotani K, Takahashi K, Ozawa K, Kunishita T, Tabira T.
    Biochem Biophys Res Commun; 1997 Nov 26; 240(3):728-31. PubMed ID: 9398634
    [Abstract] [Full Text] [Related]

  • 17. Presenilin-1 mutations associated with familial Alzheimer's disease do not disrupt protein transport from the endoplasmic reticulum to the Golgi apparatus.
    Tan Y, Hong J, Doan T, McConlogue L, Maltese WA.
    Biochim Biophys Acta; 1998 Jul 01; 1407(1):69-78. PubMed ID: 9639678
    [Abstract] [Full Text] [Related]

  • 18. Presenilin 2 expression in neuronal cells: induction during differentiation of embryonic carcinoma cells.
    Culvenor JG, Evin G, Cooney MA, Wardan H, Sharples RA, Maher F, Reed G, Diehlmann A, Weidemann A, Beyreuther K, Masters CL.
    Exp Cell Res; 2000 Mar 15; 255(2):192-206. PubMed ID: 10694435
    [Abstract] [Full Text] [Related]

  • 19. Alternative cleavage of Alzheimer-associated presenilins during apoptosis by a caspase-3 family protease.
    Kim TW, Pettingell WH, Jung YK, Kovacs DM, Tanzi RE.
    Science; 1997 Jul 18; 277(5324):373-6. PubMed ID: 9219695
    [Abstract] [Full Text] [Related]

  • 20. The influence of endoproteolytic processing of familial Alzheimer's disease presenilin 2 on abeta42 amyloid peptide formation.
    Jacobsen H, Reinhardt D, Brockhaus M, Bur D, Kocyba C, Kurt H, Grim MG, Baumeister R, Loetscher H.
    J Biol Chem; 1999 Dec 03; 274(49):35233-9. PubMed ID: 10575009
    [Abstract] [Full Text] [Related]

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