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Journal Abstract Search

354 related items for PubMed ID: 11743967

  • 1. A role for spinal, but not supraspinal, alpha(2) adrenergic receptors in the actions of improgan, a powerful, non-opioid analgesic.
    Svokos K, Nalwalk JW, Leurs R, Menge WM, Timmerman H, Hough LB.
    Brain Res; 2001 Dec 27; 923(1-2):12-9. PubMed ID: 11743967
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  • 3. Significance of GABAergic systems in the action of improgan, a non-opioid analgesic.
    Hough LB, Nalwalk JW, Leurs R, Menge WM, Timmerman H.
    Life Sci; 2001 May 04; 68(24):2751-7. PubMed ID: 11400917
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  • 7. Supraspinal and spinal delta(2) opioid receptor-mediated antinociceptive synergy is mediated by spinal alpha(2) adrenoceptors.
    Grabow TS, Hurley RW, Banfor PN, Hammond DL.
    Pain; 1999 Oct 04; 83(1):47-55. PubMed ID: 10506671
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  • 9. Antinociceptive activity of chemical congeners of improgan: optimization of side chain length leads to the discovery of a new, potent, non-opioid analgesic.
    Hough LB, de Esch IJ, Janssen E, Phillips J, Svokos K, Kern B, Trachler J, Abood ME, Leurs R, Nalwalk JW.
    Neuropharmacology; 2006 Sep 04; 51(3):447-56. PubMed ID: 16806300
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  • 10. Absence of 5-HT3 and cholinergic mechanisms in improgan antinociception.
    Nalwalk JW, Svokos K, Leurs R, Hough LB.
    Pharmacol Biochem Behav; 2005 Mar 04; 80(3):505-10. PubMed ID: 15740793
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  • 12. Brain P450 epoxygenase activity is required for the antinociceptive effects of improgan, a nonopioid analgesic.
    Hough LB, Nalwalk JW, Yang J, Conroy JL, VanAlstine MA, Yang W, Gargano J, Shan Z, Zhang SZ, Wentland MP, Phillips JG, Knapp BI, Bidlack JM, Zuiderveld OP, Leurs R, Ding X.
    Pain; 2011 Apr 04; 152(4):878-887. PubMed ID: 21316152
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  • 16. The antinociceptive effect of FR140423 in mice: involvement of spinal alpha(2)-adrenoceptors.
    Ochi T, Goto T.
    Eur J Pharmacol; 2000 Jul 21; 400(2-3):199-203. PubMed ID: 10988334
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  • 17. CC12, a high-affinity ligand for [3H]cimetidine binding, is an improgan antagonist.
    Hough LB, Nalwalk JW, Phillips JG, Kern B, Shan Z, Wentland MP, de Esch IJ, Janssen E, Barr T, Stadel R.
    Neuropharmacology; 2007 Apr 21; 52(5):1244-55. PubMed ID: 17336343
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  • 18. Spinal pharmacology of antinociception produced by microinjection of mu or delta opioid receptor agonists in the ventromedial medulla of the rat.
    Hurley RW, Banfor P, Hammond DL.
    Neuroscience; 2003 Apr 21; 118(3):789-96. PubMed ID: 12710986
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  • 19. Activation of brain stem nuclei by improgan, a non-opioid analgesic.
    Nalwalk JW, Svokos K, Taraschenko O, Leurs R, Timmerman H, Hough LB.
    Brain Res; 2004 Sep 24; 1021(2):248-55. PubMed ID: 15342273
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  • 20. Isoflurane and nociception: spinal alpha2A adrenoceptors mediate antinociception while supraspinal alpha1 adrenoceptors mediate pronociception.
    Kingery WS, Agashe GS, Guo TZ, Sawamura S, Davies MF, Clark JD, Kobilka BK, Maze M.
    Anesthesiology; 2002 Feb 24; 96(2):367-74. PubMed ID: 11818770
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