These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

111 related items for PubMed ID: 11744603

  • 1. Desacetyl-diltiazem displays severalfold higher affinity to CYP2D6 compared with CYP3A4.
    Molden E, Asberg A, Christensen H.
    Drug Metab Dispos; 2002 Jan; 30(1):1-3. PubMed ID: 11744603
    [Abstract] [Full Text] [Related]

  • 2. CYP2D6 is involved in O-demethylation of diltiazem. An in vitro study with transfected human liver cells.
    Molden E, Asberg A, Christensen H.
    Eur J Clin Pharmacol; 2000 Nov; 56(8):575-9. PubMed ID: 11151747
    [Abstract] [Full Text] [Related]

  • 3. Role of CYP3A4 in human hepatic diltiazem N-demethylation: inhibition of CYP3A4 activity by oxidized diltiazem metabolites.
    Sutton D, Butler AM, Nadin L, Murray M.
    J Pharmacol Exp Ther; 1997 Jul; 282(1):294-300. PubMed ID: 9223567
    [Abstract] [Full Text] [Related]

  • 4. Diltiazem inhibition of cytochrome P-450 3A activity is due to metabolite intermediate complex formation.
    Jones DR, Gorski JC, Hamman MA, Mayhew BS, Rider S, Hall SD.
    J Pharmacol Exp Ther; 1999 Sep; 290(3):1116-25. PubMed ID: 10454485
    [Abstract] [Full Text] [Related]

  • 5. Pharmacokinetics of diltiazem and its metabolites in relation to CYP2D6 genotype.
    Molden E, Johansen PW, Bøe GH, Bergan S, Christensen H, Rugstad HE, Rootwelt H, Reubsaet L, Lehne G.
    Clin Pharmacol Ther; 2002 Sep; 72(3):333-42. PubMed ID: 12235455
    [Abstract] [Full Text] [Related]

  • 6. Azelastine N-demethylation by cytochrome P-450 (CYP)3A4, CYP2D6, and CYP1A2 in human liver microsomes: evaluation of approach to predict the contribution of multiple CYPs.
    Nakajima M, Nakamura S, Tokudome S, Shimada N, Yamazaki H, Yokoi T.
    Drug Metab Dispos; 1999 Dec; 27(12):1381-91. PubMed ID: 10570018
    [Abstract] [Full Text] [Related]

  • 7. Identification of the rabbit and human cytochromes P-450IIIA as the major enzymes involved in the N-demethylation of diltiazem.
    Pichard L, Gillet G, Fabre I, Dalet-Beluche I, Bonfils C, Thenot JP, Maurel P.
    Drug Metab Dispos; 1990 Dec; 18(5):711-9. PubMed ID: 1981725
    [Abstract] [Full Text] [Related]

  • 8. Microsomal codeine N-demethylation: cosegregation with cytochrome P4503A4 activity.
    Caraco Y, Tateishi T, Guengerich FP, Wood AJ.
    Drug Metab Dispos; 1996 Jul; 24(7):761-4. PubMed ID: 8818573
    [Abstract] [Full Text] [Related]

  • 9. Extensive metabolism of diltiazem and P-glycoprotein-mediated efflux of desacetyl-diltiazem (M1) by rat jejunum in vitro.
    Molden E, Christensen H, Sund RB.
    Drug Metab Dispos; 2000 Feb; 28(2):107-9. PubMed ID: 10640504
    [Abstract] [Full Text] [Related]

  • 10. Different enantioselective 9-hydroxylation of risperidone by the two human CYP2D6 and CYP3A4 enzymes.
    Yasui-Furukori N, Hidestrand M, Spina E, Facciolá G, Scordo MG, Tybring G.
    Drug Metab Dispos; 2001 Oct; 29(10):1263-8. PubMed ID: 11560868
    [Abstract] [Full Text] [Related]

  • 11. An in vitro model for predicting in vivo inhibition of cytochrome P450 3A4 by metabolic intermediate complex formation.
    Mayhew BS, Jones DR, Hall SD.
    Drug Metab Dispos; 2000 Sep; 28(9):1031-7. PubMed ID: 10950845
    [Abstract] [Full Text] [Related]

  • 12. Involvement of CYP3A4 and CYP2D6 in the metabolism of haloperidol.
    Fang J, Baker GB, Silverstone PH, Coutts RT.
    Cell Mol Neurobiol; 1997 Apr; 17(2):227-33. PubMed ID: 9140699
    [Abstract] [Full Text] [Related]

  • 13. Effects of CYP3A5 and CYP2D6 genetic polymorphism on the pharmacokinetics of diltiazem and its metabolites in Chinese subjects.
    Zheng T, Su CH, Zhao J, Zhang XJ, Zhang TY, Zhang LR, Kan QC, Zhang SJ.
    Pharmazie; 2013 Apr; 68(4):257-60. PubMed ID: 23700791
    [Abstract] [Full Text] [Related]

  • 14. Expression, purification, and characterization of mouse CYP2d22.
    Yu AM, Haining RL.
    Drug Metab Dispos; 2006 Jul; 34(7):1167-74. PubMed ID: 16595712
    [Abstract] [Full Text] [Related]

  • 15. Comparative contribution to dextromethorphan metabolism by cytochrome P450 isoforms in vitro: can dextromethorphan be used as a dual probe for both CTP2D6 and CYP3A activities?
    Yu A, Haining RL.
    Drug Metab Dispos; 2001 Nov; 29(11):1514-20. PubMed ID: 11602530
    [Abstract] [Full Text] [Related]

  • 16. Characterization of human cytochrome P450 isoenzymes involved in the metabolism of vinorelbine.
    Beulz-Riché D, Grudé P, Puozzo C, Sautel F, Filaquier C, Riché C, Ratanasavanh D.
    Fundam Clin Pharmacol; 2005 Oct; 19(5):545-53. PubMed ID: 16176333
    [Abstract] [Full Text] [Related]

  • 17. Involvement of CYP3A4, CYP2C8, and CYP2D6 in the metabolism of (R)- and (S)-methadone in vitro.
    Wang JS, DeVane CL.
    Drug Metab Dispos; 2003 Jun; 31(6):742-7. PubMed ID: 12756206
    [Abstract] [Full Text] [Related]

  • 18. Quantitative contribution of CYP2D6 and CYP3A to oxycodone metabolism in human liver and intestinal microsomes.
    Lalovic B, Phillips B, Risler LL, Howald W, Shen DD.
    Drug Metab Dispos; 2004 Apr; 32(4):447-54. PubMed ID: 15039299
    [Abstract] [Full Text] [Related]

  • 19. Metabolism of the active metabolite of quetiapine, N-desalkylquetiapine in vitro.
    Bakken GV, Molden E, Knutsen K, Lunder N, Hermann M.
    Drug Metab Dispos; 2012 Sep; 40(9):1778-84. PubMed ID: 22688609
    [Abstract] [Full Text] [Related]

  • 20. Drug interactions with calcium channel blockers: possible involvement of metabolite-intermediate complexation with CYP3A.
    Ma B, Prueksaritanont T, Lin JH.
    Drug Metab Dispos; 2000 Feb; 28(2):125-30. PubMed ID: 10640508
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 6.