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351 related items for PubMed ID: 11751994
1. Multilevel dysregulation of STAT3 activation in anaplastic lymphoma kinase-positive T/null-cell lymphoma. Zhang Q, Raghunath PN, Xue L, Majewski M, Carpentieri DF, Odum N, Morris S, Skorski T, Wasik MA. J Immunol; 2002 Jan 01; 168(1):466-74. PubMed ID: 11751994 [Abstract] [Full Text] [Related]
2. Anaplastic lymphoma kinase (ALK) activates Stat3 and protects hematopoietic cells from cell death. Zamo A, Chiarle R, Piva R, Howes J, Fan Y, Chilosi M, Levy DE, Inghirami G. Oncogene; 2002 Feb 07; 21(7):1038-47. PubMed ID: 11850821 [Abstract] [Full Text] [Related]
3. Nucleophosmin/anaplastic lymphoma kinase (NPM/ALK) oncoprotein induces the T regulatory cell phenotype by activating STAT3. Kasprzycka M, Marzec M, Liu X, Zhang Q, Wasik MA. Proc Natl Acad Sci U S A; 2006 Jun 27; 103(26):9964-9. PubMed ID: 16766651 [Abstract] [Full Text] [Related]
4. Oncogenic kinase NPM/ALK induces through STAT3 expression of immunosuppressive protein CD274 (PD-L1, B7-H1). Marzec M, Zhang Q, Goradia A, Raghunath PN, Liu X, Paessler M, Wang HY, Wysocka M, Cheng M, Ruggeri BA, Wasik MA. Proc Natl Acad Sci U S A; 2008 Dec 30; 105(52):20852-7. PubMed ID: 19088198 [Abstract] [Full Text] [Related]
5. Oncogenic tyrosine kinase NPM/ALK induces activation of the rapamycin-sensitive mTOR signaling pathway. Marzec M, Kasprzycka M, Liu X, El-Salem M, Halasa K, Raghunath PN, Bucki R, Wlodarski P, Wasik MA. Oncogene; 2007 Aug 16; 26(38):5606-14. PubMed ID: 17353907 [Abstract] [Full Text] [Related]
6. Oncogenic kinase NPM/ALK induces expression of HIF1α mRNA. Marzec M, Liu X, Wong W, Yang Y, Pasha T, Kantekure K, Zhang P, Woetmann A, Cheng M, Odum N, Wasik MA. Oncogene; 2011 Mar 17; 30(11):1372-8. PubMed ID: 21102525 [Abstract] [Full Text] [Related]
7. Inhibition of ALK enzymatic activity in T-cell lymphoma cells induces apoptosis and suppresses proliferation and STAT3 phosphorylation independently of Jak3. Marzec M, Kasprzycka M, Ptasznik A, Wlodarski P, Zhang Q, Odum N, Wasik MA. Lab Invest; 2005 Dec 17; 85(12):1544-54. PubMed ID: 16170336 [Abstract] [Full Text] [Related]
8. Role of signal transducer and activator of transcription 5 in nucleophosmin/ anaplastic lymphoma kinase-mediated malignant transformation of lymphoid cells. Nieborowska-Skorska M, Slupianek A, Xue L, Zhang Q, Raghunath PN, Hoser G, Wasik MA, Morris SW, Skorski T. Cancer Res; 2001 Sep 01; 61(17):6517-23. PubMed ID: 11522649 [Abstract] [Full Text] [Related]
9. Malignant transformation of CD4+ T lymphocytes mediated by oncogenic kinase NPM/ALK recapitulates IL-2-induced cell signaling and gene expression reprogramming. Marzec M, Halasa K, Liu X, Wang HY, Cheng M, Baldwin D, Tobias JW, Schuster SJ, Woetmann A, Zhang Q, Turner SD, Ødum N, Wasik MA. J Immunol; 2013 Dec 15; 191(12):6200-7. PubMed ID: 24218456 [Abstract] [Full Text] [Related]
10. Induction of Transcriptional Inhibitor HES1 and the Related Repression of Tumor-Suppressor TXNIP Are Important Components of Cell-Transformation Program Imposed by Oncogenic Kinase NPM-ALK. Zhang Q, Wang HY, Nayak A, Nunez-Cruz S, Slupianek A, Liu X, Basappa J, Fan JS, Chekol S, Nejati R, Bogusz AM, Turner SD, Swaminathan K, Wasik MA. Am J Pathol; 2022 Aug 15; 192(8):1186-1198. PubMed ID: 35640677 [Abstract] [Full Text] [Related]
11. Selective inhibition of STAT3 induces apoptosis and G(1) cell cycle arrest in ALK-positive anaplastic large cell lymphoma. Amin HM, McDonnell TJ, Ma Y, Lin Q, Fujio Y, Kunisada K, Leventaki V, Das P, Rassidakis GZ, Cutler C, Medeiros LJ, Lai R. Oncogene; 2004 Jul 15; 23(32):5426-34. PubMed ID: 15184887 [Abstract] [Full Text] [Related]
12. Signal transducer and activator of transcription-3 activation contributes to high tissue inhibitor of metalloproteinase-1 expression in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma. Lai R, Rassidakis GZ, Medeiros LJ, Ramdas L, Goy AH, Cutler C, Fujio Y, Kunisada K, Amin HM, Gilles F. Am J Pathol; 2004 Jun 15; 164(6):2251-8. PubMed ID: 15161657 [Abstract] [Full Text] [Related]
13. STAT1 is phosphorylated and downregulated by the oncogenic tyrosine kinase NPM-ALK in ALK-positive anaplastic large-cell lymphoma. Wu C, Molavi O, Zhang H, Gupta N, Alshareef A, Bone KM, Gopal K, Wu F, Lewis JT, Douglas DN, Kneteman NM, Lai R. Blood; 2015 Jul 16; 126(3):336-45. PubMed ID: 25921060 [Abstract] [Full Text] [Related]
14. NPM-ALK up-regulates iNOS expression through a STAT3/microRNA-26a-dependent mechanism. Zhu H, Vishwamitra D, Curry CV, Manshouri R, Diao L, Khan A, Amin HM. J Pathol; 2013 May 16; 230(1):82-94. PubMed ID: 23338972 [Abstract] [Full Text] [Related]
15. Anaplastic lymphoma kinase (ALK)-induced malignancies: novel mechanisms of cell transformation and potential therapeutic approaches. Wasik MA, Zhang Q, Marzec M, Kasprzycka M, Wang HY, Liu X. Semin Oncol; 2009 Apr 16; 36(2 Suppl 1):S27-35. PubMed ID: 19393833 [Abstract] [Full Text] [Related]
16. Role of phosphatidylinositol 3-kinase-Akt pathway in nucleophosmin/anaplastic lymphoma kinase-mediated lymphomagenesis. Slupianek A, Nieborowska-Skorska M, Hoser G, Morrione A, Majewski M, Xue L, Morris SW, Wasik MA, Skorski T. Cancer Res; 2001 Mar 01; 61(5):2194-9. PubMed ID: 11280786 [Abstract] [Full Text] [Related]
17. Nucleophosmin-anaplastic lymphoma kinase: the ultimate oncogene and therapeutic target. Werner MT, Zhao C, Zhang Q, Wasik MA. Blood; 2017 Feb 16; 129(7):823-831. PubMed ID: 27879258 [Abstract] [Full Text] [Related]
18. Nucleophosmin-anaplastic lymphoma kinase of anaplastic large-cell lymphoma recruits, activates, and uses pp60c-src to mediate its mitogenicity. Cussac D, Greenland C, Roche S, Bai RY, Duyster J, Morris SW, Delsol G, Allouche M, Payrastre B. Blood; 2004 Feb 15; 103(4):1464-71. PubMed ID: 14563642 [Abstract] [Full Text] [Related]
19. Nucleophosmin-anaplastic lymphoma kinase of large-cell anaplastic lymphoma is a constitutively active tyrosine kinase that utilizes phospholipase C-gamma to mediate its mitogenicity. Bai RY, Dieter P, Peschel C, Morris SW, Duyster J. Mol Cell Biol; 1998 Dec 15; 18(12):6951-61. PubMed ID: 9819383 [Abstract] [Full Text] [Related]
20. Constitutive activation of Jak2 contributes to proliferation and resistance to apoptosis in NPM/ALK-transformed cells. Ruchatz H, Coluccia AM, Stano P, Marchesi E, Gambacorti-Passerini C. Exp Hematol; 2003 Apr 15; 31(4):309-15. PubMed ID: 12691918 [Abstract] [Full Text] [Related] Page: [Next] [New Search]