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238 related items for PubMed ID: 11765016

  • 1. Dose-dependent differences in the profile of mutations induced by carcinogenic (R,S,S,R) bay- and fjord-region diol epoxides of polycyclic aromatic hydrocarbons.
    Conney AH, Chang RL, Cui XX, Schiltz M, Yagi H, Jerina DM, Wei SJ.
    Adv Exp Med Biol; 2001; 500():697-707. PubMed ID: 11765016
    [Abstract] [Full Text] [Related]

  • 2. Glutathione conjugation of bay- and fjord-region diol epoxides of polycyclic aromatic hydrocarbons by glutathione transferases M1-1 and P1-1.
    Sundberg K, Widersten M, Seidel A, Mannervik B, Jernström B.
    Chem Res Toxicol; 1997 Nov; 10(11):1221-7. PubMed ID: 9403173
    [Abstract] [Full Text] [Related]

  • 3. Mutagenic selectivity at the HPRT locus in V-79 cells: comparison of mutations caused by bay-region benzo[a]pyrene 7,8-diol-9,-10-epoxide enantiomers with high and low carcinogenic activity.
    Wei SJ, Chang RL, Hennig E, Cui XX, Merkler KA, Wong CQ, Yagi H, Jerina DM, Conney AH.
    Carcinogenesis; 1994 Aug; 15(8):1729-35. PubMed ID: 8055656
    [Abstract] [Full Text] [Related]

  • 4. Fjord- and bay-region diol-epoxides investigated for stability, SOS induction in Escherichia coli, and mutagenicity in Salmonella typhimurium and mammalian cells.
    Glatt H, Piée A, Pauly K, Steinbrecher T, Schrode R, Oesch F, Seidel A.
    Cancer Res; 1991 Mar 15; 51(6):1659-67. PubMed ID: 1900215
    [Abstract] [Full Text] [Related]

  • 5. Tumorigenicity of four optically active bay-region 3,4-diol 1, 2-epoxides and other derivatives of the nitrogen heterocycle dibenz[c,h]acridine on mouse skin and in newborn mice.
    Chang RL, Wood AW, Kumar S, Lehr RE, Shirai N, Jerina DM, Conney AH.
    Carcinogenesis; 2000 Nov 15; 21(11):1997-2003. PubMed ID: 11062160
    [Abstract] [Full Text] [Related]

  • 6. Detoxification of optically active bay- and fjord-region polycyclic aromatic hydrocarbon dihydrodiol epoxides by human glutathione transferase P1-1 expressed in Chinese hamster V79 cells.
    Seidel A, Friedberg T, Löllmann B, Schwierzok A, Funk M, Frank H, Holler R, Oesch F, Glatt H.
    Carcinogenesis; 1998 Nov 15; 19(11):1975-81. PubMed ID: 9855012
    [Abstract] [Full Text] [Related]

  • 7. Glutathione S-transferase A1-1-catalysed conjugation of bay and fjord region diol epoxides or polycyclic aromatic hydrocarbons with glutathione.
    Jernstrom B, Funk M, Frank H, Mannervik B, Seidel A.
    Carcinogenesis; 1996 Jul 15; 17(7):1491-8. PubMed ID: 8706254
    [Abstract] [Full Text] [Related]

  • 8. Unrepaired fjord region polycyclic aromatic hydrocarbon-DNA adducts in ras codon 61 mutational hot spots.
    Buterin T, Hess MT, Luneva N, Geacintov NE, Amin S, Kroth H, Seidel A, Naegeli H.
    Cancer Res; 2000 Apr 01; 60(7):1849-56. PubMed ID: 10766171
    [Abstract] [Full Text] [Related]

  • 9. Bacterial and mammalian cell mutagenicity of four optically active bay-region 3,4-diol-1,2-epoxides and other derivatives of the nitrogen heterocycle dibenz[c,h]acridine.
    Wood AW, Chang RL, Levin W, Kumar S, Shirai N, Jerina DM, Lehr RE, Conney AH.
    Cancer Res; 1986 Jun 01; 46(6):2760-6. PubMed ID: 3516386
    [Abstract] [Full Text] [Related]

  • 10. Inhibition of the mutagenicity of bay-region diol epoxides of polycyclic aromatic hydrocarbons by naturally occurring plant phenols: exceptional activity of ellagic acid.
    Wood AW, Huang MT, Chang RL, Newmark HL, Lehr RE, Yagi H, Sayer JM, Jerina DM, Conney AH.
    Proc Natl Acad Sci U S A; 1982 Sep 01; 79(18):5513-7. PubMed ID: 6752950
    [Abstract] [Full Text] [Related]

  • 11. Relationship between mutagenicity and DNA adduct formation in mammalian cells for fjord- and bay-region diol-epoxides of polycyclic aromatic hydrocarbons.
    Phillips DH, Hewer A, Seidel A, Steinbrecher T, Schrode R, Oesch F, Glatt H.
    Chem Biol Interact; 1991 Sep 01; 80(2):177-86. PubMed ID: 1934148
    [Abstract] [Full Text] [Related]

  • 12. Characterization of the mutational profile of (+)-7R,8S-dihydroxy-9S, 10R-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene at the hypoxanthine (guanine) phosphoribosyltransferase gene in repair-deficient Chinese hamster V-H1 cells.
    Schiltz M, Cui XX, Lu YP, Yagi H, Jerina DM, Zdzienicka MZ, Chang RL, Conney AH, Wei SJ.
    Carcinogenesis; 1999 Dec 01; 20(12):2279-86. PubMed ID: 10590220
    [Abstract] [Full Text] [Related]

  • 13. Reactivity and tumorigenicity of bay-region diol epoxides derived from polycyclic aromatic hydrocarbons.
    Jerina DM, Sayer JM, Agarwal SK, Yagi H, Levin W, Wood AW, Conney AH, Pruess-Schwartz D, Baird WM, Pigott MA.
    Adv Exp Med Biol; 1986 Dec 01; 197():11-30. PubMed ID: 3490131
    [Abstract] [Full Text] [Related]

  • 14. Dose-dependent differences in the profile of mutations induced by (+)-7R,8S-dihydroxy-9S,10R-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene in the coding region of the hypoxanthine (guanine) phosphoribosyltransferase gene in Chinese hamster V-79 cells.
    Wei SJ, Chang RL, Bhachech N, Cui XX, Merkler KA, Wong CQ, Hennig E, Yagi H, Jerina DM, Conney AH.
    Cancer Res; 1993 Jul 15; 53(14):3294-301. PubMed ID: 8324741
    [Abstract] [Full Text] [Related]

  • 15. Metabolism of benzo[c]chrysene and comparative mammary gland tumorigenesis of benzo[c]chrysene bay and fjord region diol epoxides in female CD rats.
    Amin S, Lin JM, Krzeminski J, Boyiri T, Desai D, El-Bayoumy K.
    Chem Res Toxicol; 2003 Feb 15; 16(2):227-31. PubMed ID: 12588194
    [Abstract] [Full Text] [Related]

  • 16. Mutagenicity of the enantiomers of the diastereomeric bay-region benzo(c)phenanthrene 3,4-diol-1,2-epoxides in bacterial and mammalian cells.
    Wood AW, Chang RL, Levin W, Thakker DR, Yagi H, Sayer JM, Jerina DM, Conney AH.
    Cancer Res; 1984 Jun 15; 44(6):2320-4. PubMed ID: 6372992
    [Abstract] [Full Text] [Related]

  • 17. Dose-dependent mutation profile in the c-Ha-ras proto-oncogene of skin tumors in mice initiated with benzo[a]pyrene.
    Wei SJ, Chang RL, Merkler KA, Gwynne M, Cui XX, Murthy B, Huang MT, Xie JG, Lu YP, Lou YR, Jerina DM, Conney AH.
    Carcinogenesis; 1999 Sep 15; 20(9):1689-96. PubMed ID: 10469612
    [Abstract] [Full Text] [Related]

  • 18. Mutagenicity of the bay-region diol-epoxides and other benzo-ring derivatives of dibenzo(a,h)pyrene and dibenzo(a,i)pyrene.
    Wood AW, Chang RL, Levin W, Ryan DE, Thomas PE, Lehr RE, Kumar S, Sardella DJ, Boger E, Yagi H, Sayer JM, Jerina DM, Conney AH.
    Cancer Res; 1981 Jul 15; 41(7):2589-97. PubMed ID: 7018665
    [Abstract] [Full Text] [Related]

  • 19. Dose-dependent differences in the mutational profiles of (-)-(1R,2S,3S,4R)-3,4-dihydroxy-1, 2-epoxy-1,2,3,4-tetrahydrobenzo[c]phenanthrene and its less carcinogenic enantiomer.
    Wei SJ, Chang RL, Cui XX, Merkler KA, Wong CQ, Yagi H, Jerina DM, Conney AH.
    Cancer Res; 1996 Aug 15; 56(16):3695-703. PubMed ID: 8706010
    [Abstract] [Full Text] [Related]

  • 20. Potent mammary carcinogenicity in female CD rats of a fjord region diol-epoxide of benzo[c]phenanthrene compared to a bay region diol-epoxide of benzo[a]pyrene.
    Hecht SS, el-Bayoumy K, Rivenson A, Amin S.
    Cancer Res; 1994 Jan 01; 54(1):21-4. PubMed ID: 8261440
    [Abstract] [Full Text] [Related]

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