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Journal Abstract Search

277 related items for PubMed ID: 11767949

  • 1. Osmolytes as modulators of conformational changes in serpins.
    Chow MK, Devlin GL, Bottomley SP.
    Biol Chem; 2001 Nov; 382(11):1593-9. PubMed ID: 11767949
    [Abstract] [Full Text] [Related]

  • 2. Prevention of polymerization of M and Z alpha1-Antitrypsin (alpha1-AT) with trimethylamine N-oxide. Implications for the treatment of alpha1-at deficiency.
    Devlin GL, Parfrey H, Tew DJ, Lomas DA, Bottomley SP.
    Am J Respir Cell Mol Biol; 2001 Jun; 24(6):727-32. PubMed ID: 11415938
    [Abstract] [Full Text] [Related]

  • 3. Singular efficacy of trimethylamine N-oxide to counter protein destabilization in ice.
    Strambini GB, Gonnelli M.
    Biochemistry; 2008 Mar 18; 47(11):3322-31. PubMed ID: 18293933
    [Abstract] [Full Text] [Related]

  • 4. Different conformational changes within the F-helix occur during serpin folding, polymerization, and proteinase inhibition.
    Cabrita LD, Dai W, Bottomley SP.
    Biochemistry; 2004 Aug 03; 43(30):9834-9. PubMed ID: 15274637
    [Abstract] [Full Text] [Related]

  • 5. Kinetic instability of the serpin Z alpha1-antitrypsin promotes aggregation.
    Knaupp AS, Levina V, Robertson AL, Pearce MC, Bottomley SP.
    J Mol Biol; 2010 Feb 19; 396(2):375-83. PubMed ID: 19944704
    [Abstract] [Full Text] [Related]

  • 6. Role of Lys335 in the metastability and function of inhibitory serpins.
    Im H, Yu MH.
    Protein Sci; 2000 May 19; 9(5):934-41. PubMed ID: 10850803
    [Abstract] [Full Text] [Related]

  • 7. Alpha 1-antitrypsin polymerisation can occur by both loop A and C sheet mechanisms.
    Bottomley SP, Hopkins PC, Whisstock JC.
    Biochem Biophys Res Commun; 1998 Oct 09; 251(1):1-5. PubMed ID: 9790897
    [Abstract] [Full Text] [Related]

  • 8. Bypassing the kinetic trap of serpin protein folding by loop extension.
    Im H, Ahn HY, Yu MH.
    Protein Sci; 2000 Aug 09; 9(8):1497-502. PubMed ID: 10975571
    [Abstract] [Full Text] [Related]

  • 9. Probing the equilibrium denaturation of the serpin alpha(1)-antitrypsin with single tryptophan mutants; evidence for structure in the urea unfolded state.
    Tew DJ, Bottomley SP.
    J Mol Biol; 2001 Nov 09; 313(5):1161-9. PubMed ID: 11700071
    [Abstract] [Full Text] [Related]

  • 10. Osmolyte mixtures have different effects than individual osmolytes on protein folding and functional activity.
    Warepam M, Singh LR.
    Arch Biochem Biophys; 2015 May 01; 573():77-83. PubMed ID: 25817170
    [Abstract] [Full Text] [Related]

  • 11. Conformational changes in serpins: I. The native and cleaved conformations of alpha(1)-antitrypsin.
    Whisstock JC, Skinner R, Carrell RW, Lesk AM.
    J Mol Biol; 2000 Feb 18; 296(2):685-99. PubMed ID: 10669617
    [Abstract] [Full Text] [Related]

  • 12. Engineering thermostability in serine protease inhibitors.
    Im H, Ryu MJ, Yu MH.
    Protein Eng Des Sel; 2004 Apr 18; 17(4):325-31. PubMed ID: 15126675
    [Abstract] [Full Text] [Related]

  • 13. Viscous drag as the source of active site perturbation during protease translocation: insights into how inhibitory processes are controlled by serpin metastability.
    Shin JS, Yu MH.
    J Mol Biol; 2006 Jun 02; 359(2):378-89. PubMed ID: 16626735
    [Abstract] [Full Text] [Related]

  • 14. Probing the local conformational change of alpha1-antitrypsin.
    Baek JH, Im H, Kang UB, Seong KM, Lee C, Kim J, Yu MH.
    Protein Sci; 2007 Sep 02; 16(9):1842-50. PubMed ID: 17660256
    [Abstract] [Full Text] [Related]

  • 15. Conformational changes in serpins: I. The native and cleaved conformations of alpha(1)-antitrypsin.
    Whisstock JC, Skinner R, Carrell RW, Lesk AM.
    J Mol Biol; 2000 Jan 21; 295(3):651-65. PubMed ID: 10623554
    [Abstract] [Full Text] [Related]

  • 16. Role of the connectivity of secondary structure segments in the folding of alpha(1)-antitrypsin.
    Lee C, Seo EJ, Yu MH.
    Biochem Biophys Res Commun; 2001 Sep 28; 287(3):636-41. PubMed ID: 11563842
    [Abstract] [Full Text] [Related]

  • 17. DNA induces folding in alpha-synuclein: understanding the mechanism using chaperone property of osmolytes.
    Hegde ML, Rao KS.
    Arch Biochem Biophys; 2007 Aug 01; 464(1):57-69. PubMed ID: 17537399
    [Abstract] [Full Text] [Related]

  • 18. Serpin polymerization and its role in disease--the molecular basis of alpha1-antitrypsin deficiency.
    Knaupp AS, Bottomley SP.
    IUBMB Life; 2009 Jan 01; 61(1):1-5. PubMed ID: 18785256
    [Abstract] [Full Text] [Related]

  • 19. Practical genetics: alpha-1-antitrypsin deficiency and the serpinopathies.
    Crowther DC, Belorgey D, Miranda E, Kinghorn KJ, Sharp LK, Lomas DA.
    Eur J Hum Genet; 2004 Mar 01; 12(3):167-72. PubMed ID: 14694355
    [Abstract] [Full Text] [Related]

  • 20. Characterization and suppression of dysfunctional human alpha1-antitrypsin variants.
    Kim MJ, Jung CH, Im H.
    Biochem Biophys Res Commun; 2006 Apr 28; 343(1):295-302. PubMed ID: 16540089
    [Abstract] [Full Text] [Related]

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