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Journal Abstract Search

228 related items for PubMed ID: 11774295

  • 1. Selection of high affinity human neutralizing antibodies to VEGFR2 from a large antibody phage display library for antiangiogenesis therapy.
    Lu D, Jimenez X, Zhang H, Bohlen P, Witte L, Zhu Z.
    Int J Cancer; 2002 Jan 20; 97(3):393-9. PubMed ID: 11774295
    [Abstract] [Full Text] [Related]

  • 2. Tailoring in vitro selection for a picomolar affinity human antibody directed against vascular endothelial growth factor receptor 2 for enhanced neutralizing activity.
    Lu D, Shen J, Vil MD, Zhang H, Jimenez X, Bohlen P, Witte L, Zhu Z.
    J Biol Chem; 2003 Oct 31; 278(44):43496-507. PubMed ID: 12917408
    [Abstract] [Full Text] [Related]

  • 3. Complete inhibition of vascular endothelial growth factor (VEGF) activities with a bifunctional diabody directed against both VEGF kinase receptors, fms-like tyrosine kinase receptor and kinase insert domain-containing receptor.
    Lu D, Jimenez X, Zhang H, Wu Y, Bohlen P, Witte L, Zhu Z.
    Cancer Res; 2001 Oct 01; 61(19):7002-8. PubMed ID: 11585724
    [Abstract] [Full Text] [Related]

  • 4. Inhibition of vascular endothelial growth factor-induced receptor activation with anti-kinase insert domain-containing receptor single-chain antibodies from a phage display library.
    Zhu Z, Rockwell P, Lu D, Kotanides H, Pytowski B, Hicklin DJ, Bohlen P, Witte L.
    Cancer Res; 1998 Aug 01; 58(15):3209-14. PubMed ID: 9699643
    [Abstract] [Full Text] [Related]

  • 5. Inhibition of vascular endothelial growth factor induced mitogenesis of human endothelial cells by a chimeric anti-kinase insert domain-containing receptor antibody.
    Zhu Z, Lu D, Kotanides H, Santiago A, Jimenez X, Simcox T, Hicklin DJ, Bohlen P, Witte L.
    Cancer Lett; 1999 Mar 01; 136(2):203-13. PubMed ID: 10355750
    [Abstract] [Full Text] [Related]

  • 6. Inhibition of human leukemia in an animal model with human antibodies directed against vascular endothelial growth factor receptor 2. Correlation between antibody affinity and biological activity.
    Zhu Z, Hattori K, Zhang H, Jimenez X, Ludwig DL, Dias S, Kussie P, Koo H, Kim HJ, Lu D, Liu M, Tejada R, Friedrich M, Bohlen P, Witte L, Rafii S.
    Leukemia; 2003 Mar 01; 17(3):604-11. PubMed ID: 12646950
    [Abstract] [Full Text] [Related]

  • 7. Identification of the residues in the extracellular region of KDR important for interaction with vascular endothelial growth factor and neutralizing anti-KDR antibodies.
    Lu D, Kussie P, Pytowski B, Persaud K, Bohlen P, Witte L, Zhu Z.
    J Biol Chem; 2000 May 12; 275(19):14321-30. PubMed ID: 10799512
    [Abstract] [Full Text] [Related]

  • 8. Anti-VEGFR-2 scFvs for cell isolation. Single-chain antibodies recognizing the human vascular endothelial growth factor receptor-2 (VEGFR-2/flk-1) on the surface of primary endothelial cells and preselected CD34+ cells from cord blood.
    Böldicke T, Tesar M, Griesel C, Rohde M, Gröne HJ, Waltenberger J, Kollet O, Lapidot T, Yayon A, Weich H.
    Stem Cells; 2001 May 12; 19(1):24-36. PubMed ID: 11209088
    [Abstract] [Full Text] [Related]

  • 9. Identification of a peptide blocking vascular endothelial growth factor (VEGF)-mediated angiogenesis.
    Binétruy-Tournaire R, Demangel C, Malavaud B, Vassy R, Rouyre S, Kraemer M, Plouët J, Derbin C, Perret G, Mazié JC.
    EMBO J; 2000 Apr 03; 19(7):1525-33. PubMed ID: 10747021
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  • 12. A vascular endothelial growth factor high affinity receptor 1-specific peptide with antiangiogenic activity identified using a phage display peptide library.
    El-Mousawi M, Tchistiakova L, Yurchenko L, Pietrzynski G, Moreno M, Stanimirovic D, Ahmad D, Alakhov V.
    J Biol Chem; 2003 Nov 21; 278(47):46681-91. PubMed ID: 12954624
    [Abstract] [Full Text] [Related]

  • 13. KDR activation is crucial for VEGF165-mediated Ca2+ mobilization in human umbilical vein endothelial cells.
    Cunningham SA, Tran TM, Arrate MP, Bjercke R, Brock TA.
    Am J Physiol; 1999 Jan 21; 276(1):C176-81. PubMed ID: 9886933
    [Abstract] [Full Text] [Related]

  • 14. Monoclonal antibodies targeting the VEGF receptor-2 (Flk1/KDR) as an anti-angiogenic therapeutic strategy.
    Witte L, Hicklin DJ, Zhu Z, Pytowski B, Kotanides H, Rockwell P, Böhlen P.
    Cancer Metastasis Rev; 1998 Jun 21; 17(2):155-61. PubMed ID: 9770111
    [Abstract] [Full Text] [Related]

  • 15. Roles of two VEGF receptors, Flt-1 and KDR, in the signal transduction of VEGF effects in human vascular endothelial cells.
    Kanno S, Oda N, Abe M, Terai Y, Ito M, Shitara K, Tabayashi K, Shibuya M, Sato Y.
    Oncogene; 2000 Apr 20; 19(17):2138-46. PubMed ID: 10815805
    [Abstract] [Full Text] [Related]

  • 16. Acquired antagonistic activity of a bispecific diabody directed against two different epitopes on vascular endothelial growth factor receptor 2.
    Lu D, Kotanides H, Jimenez X, Zhou Q, Persaud K, Bohlen P, Witte L, Zhu Z.
    J Immunol Methods; 1999 Nov 19; 230(1-2):159-71. PubMed ID: 10594363
    [Abstract] [Full Text] [Related]

  • 17. Human/mouse cross-reactive anti-VEGF receptor 2 recombinant antibodies selected from an immune b9 allotype rabbit antibody library.
    Popkov M, Jendreyko N, Gonzalez-Sapienza G, Mage RG, Rader C, Barbas CF.
    J Immunol Methods; 2004 May 19; 288(1-2):149-64. PubMed ID: 15183093
    [Abstract] [Full Text] [Related]

  • 18. Targeting of endothelial KDR receptors with 3G2 immunoliposomes in vitro.
    Benzinger P, Martiny-Baron G, Reusch P, Siemeister G, Kley JT, Marmé D, Unger C, Massing U.
    Biochim Biophys Acta; 2000 Jun 01; 1466(1-2):71-8. PubMed ID: 10825432
    [Abstract] [Full Text] [Related]

  • 19. Production of neutralizing monoclonal antibody against human vascular endothelial growth factor receptor II.
    Li R, Xiong DS, Shao XF, Liu J, Xu YF, Xu YS, Liu HZ, Zhu ZP, Yang CZ.
    Acta Pharmacol Sin; 2004 Oct 01; 25(10):1292-8. PubMed ID: 15456530
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