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Journal Abstract Search

241 related items for PubMed ID: 11779231

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  • 5. Chiral mutagenesis of insulin's hidden receptor-binding surface: structure of an allo-isoleucine(A2) analogue.
    Xu B, Hua QX, Nakagawa SH, Jia W, Chu YC, Katsoyannis PG, Weiss MA.
    J Mol Biol; 2002 Feb 22; 316(3):435-41. PubMed ID: 11866509
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  • 6. Importance of the solvent-exposed residues of the insulin B chain alpha-helix for receptor binding.
    Glendorf T, Sørensen AR, Nishimura E, Pettersson I, Kjeldsen T.
    Biochemistry; 2008 Apr 22; 47(16):4743-51. PubMed ID: 18376848
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  • 7. Design of an insulin analog with enhanced receptor binding selectivity: rationale, structure, and therapeutic implications.
    Zhao M, Wan ZL, Whittaker L, Xu B, Phillips NB, Katsoyannis PG, Ismail-Beigi F, Whittaker J, Weiss MA.
    J Biol Chem; 2009 Nov 13; 284(46):32178-87. PubMed ID: 19773552
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  • 8. Crystal structure of allo-Ile(A2)-insulin, an inactive chiral analogue: implications for the mechanism of receptor binding.
    Wan ZL, Xu B, Chu YC, Katsoyannis PG, Weiss MA.
    Biochemistry; 2003 Nov 11; 42(44):12770-83. PubMed ID: 14596591
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  • 9. Mini-proinsulin and mini-IGF-I: homologous protein sequences encoding non-homologous structures.
    Hua QX, Hu SQ, Jia W, Chu YC, Burke GT, Wang SH, Wang RY, Katsoyannis PG, Weiss MA.
    J Mol Biol; 1998 Mar 20; 277(1):103-18. PubMed ID: 9514738
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  • 10. The relationship between insulin bioactivity and structure in the NH2-terminal A-chain helix.
    Olsen HB, Ludvigsen S, Kaarsholm NC.
    J Mol Biol; 1998 Nov 27; 284(2):477-88. PubMed ID: 9813131
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  • 11. Mapping the functional surface of insulin by design: structure and function of a novel A-chain analogue.
    Hua QX, Hu SQ, Frank BH, Jia W, Chu YC, Wang SH, Burke GT, Katsoyannis PG, Weiss MA.
    J Mol Biol; 1996 Nov 29; 264(2):390-403. PubMed ID: 8951384
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  • 12. Ligand-induced activation of the insulin receptor: a multi-step process involving structural changes in both the ligand and the receptor.
    Ward CW, Lawrence MC.
    Bioessays; 2009 Apr 29; 31(4):422-34. PubMed ID: 19274663
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  • 13. Diabetes mellitus due to misfolding of a beta-cell transcription factor: stereospecific frustration of a Schellman motif in HNF-1alpha.
    Narayana N, Phillips NB, Hua QX, Jia W, Weiss MA.
    J Mol Biol; 2006 Sep 22; 362(3):414-29. PubMed ID: 16930618
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  • 14. Chiral mutagenesis of insulin. Foldability and function are inversely regulated by a stereospecific switch in the B chain.
    Nakagawa SH, Zhao M, Hua QX, Hu SQ, Wan ZL, Jia W, Weiss MA.
    Biochemistry; 2005 Apr 05; 44(13):4984-99. PubMed ID: 15794637
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  • 15. Hierarchical protein "un-design": insulin's intrachain disulfide bridge tethers a recognition alpha-helix.
    Weiss MA, Hua QX, Jia W, Chu YC, Wang RY, Katsoyannis PG.
    Biochemistry; 2000 Dec 19; 39(50):15429-40. PubMed ID: 11112528
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  • 16. Receptor binding redefined by a structural switch in a mutant human insulin.
    Hua QX, Shoelson SE, Kochoyan M, Weiss MA.
    Nature; 1991 Nov 21; 354(6350):238-41. PubMed ID: 1961250
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  • 17. pI-shifted insulin analogs with extended in vivo time action and favorable receptor selectivity.
    Kohn WD, Micanovic R, Myers SL, Vick AM, Kahl SD, Zhang L, Strifler BA, Li S, Shang J, Beals JM, Mayer JP, DiMarchi RD.
    Peptides; 2007 Apr 21; 28(4):935-48. PubMed ID: 17328992
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  • 18. Incorporating receptor flexibility in the molecular design of protein interfaces.
    Li L, Liang S, Pilcher MM, Meroueh SO.
    Protein Eng Des Sel; 2009 Sep 21; 22(9):575-86. PubMed ID: 19643976
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  • 19. Insulin and its receptor: structure, function and evolution.
    De Meyts P.
    Bioessays; 2004 Dec 21; 26(12):1351-62. PubMed ID: 15551269
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  • 20. Stability of cyclic beta-hairpins: asymmetric contributions from side chains of a hydrogen-bonded cross-strand residue pair.
    Russell SJ, Blandl T, Skelton NJ, Cochran AG.
    J Am Chem Soc; 2003 Jan 15; 125(2):388-95. PubMed ID: 12517150
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