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546 related items for PubMed ID: 11786485

  • 1. Effect of NXY-059 on infarct volume after transient or permanent middle cerebral artery occlusion in the rat; studies on dose, plasma concentration and therapeutic time window.
    Sydserff SG, Borelli AR, Green AR, Cross AJ.
    Br J Pharmacol; 2002 Jan; 135(1):103-12. PubMed ID: 11786485
    [Abstract] [Full Text] [Related]

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  • 3. Neuroprotective effects of a novel nitrone, NXY-059, after transient focal cerebral ischemia in the rat.
    Kuroda S, Tsuchidate R, Smith ML, Maples KR, Siesjö BK.
    J Cereb Blood Flow Metab; 1999 Jul; 19(7):778-87. PubMed ID: 10413033
    [Abstract] [Full Text] [Related]

  • 4. Brain penetration of the novel free radical trapping neuroprotectant NXY-059 in rats subjected to permanent focal ischemia.
    Green AR, Lanbeck-Vallén K, Ashwood T, Lundquist S, Lindström Böö E, Jonasson H, Campbell M.
    Brain Res; 2006 Feb 09; 1072(1):224-6. PubMed ID: 16448628
    [Abstract] [Full Text] [Related]

  • 5. Functional and histological evidence for the protective effect of NXY-059 in a primate model of stroke when given 4 hours after occlusion.
    Marshall JW, Cummings RM, Bowes LJ, Ridley RM, Green AR.
    Stroke; 2003 Sep 09; 34(9):2228-33. PubMed ID: 12920263
    [Abstract] [Full Text] [Related]

  • 6. Neuroprotection by 2-h postischemia administration of two free radical scavengers, alpha-phenyl-n-tert-butyl-nitrone (PBN) and N-tert-butyl-(2-sulfophenyl)-nitrone (S-PBN), in rats subjected to focal embolic cerebral ischemia.
    Yang Y, Li Q, Shuaib A.
    Exp Neurol; 2000 May 09; 163(1):39-45. PubMed ID: 10785442
    [Abstract] [Full Text] [Related]

  • 7. High-dose methylprednisolone treatment in experimental focal cerebral ischemia.
    Slivka AP, Murphy EJ.
    Exp Neurol; 2001 Jan 09; 167(1):166-72. PubMed ID: 11161604
    [Abstract] [Full Text] [Related]

  • 8. Lidocaine attenuates apoptosis in the ischemic penumbra and reduces infarct size after transient focal cerebral ischemia in rats.
    Lei B, Popp S, Capuano-Waters C, Cottrell JE, Kass IS.
    Neuroscience; 2004 Jan 09; 125(3):691-701. PubMed ID: 15099683
    [Abstract] [Full Text] [Related]

  • 9. NXY-059, a nitrone with free radical trapping properties inhibits release of cytochrome c after focal cerebral ischemia.
    Han M, He QP, Yong G, Siesjö BK, Li PA.
    Cell Mol Biol (Noisy-le-grand); 2003 Dec 09; 49(8):1249-52. PubMed ID: 14983994
    [Abstract] [Full Text] [Related]

  • 10. Effects of isradipine, an L-type calcium channel blocker on permanent and transient focal cerebral ischemia in spontaneously hypertensive rats.
    Campbell CA, Mackay KB, Patel S, King PD, Stretton JL, Hadingham SJ, Hamilton TC.
    Exp Neurol; 1997 Nov 09; 148(1):45-50. PubMed ID: 9398449
    [Abstract] [Full Text] [Related]

  • 11. Dose finding study of intravenous magnesium sulphate in transient focal cerebral ischemia in rats.
    Westermaier T, Zausinger S, Baethmann A, Schmid-Elsaesser R.
    Acta Neurochir (Wien); 2005 May 09; 147(5):525-32; discussion 532. PubMed ID: 15838594
    [Abstract] [Full Text] [Related]

  • 12. DY-9760e, a novel calmodulin antagonist, reduces infarction after permanent focal cerebral ischemia in rats.
    Sato T, Takamori H, Shirasaki Y.
    Pharmacology; 2004 May 09; 71(1):38-45. PubMed ID: 15051921
    [Abstract] [Full Text] [Related]

  • 13. SB 234551 selective ET(A) receptor antagonism: perfusion/diffusion MRI used to define treatable stroke model, time to treatment and mechanism of protection.
    Legos JJ, Lenhard SC, Haimbach RE, Schaeffer TR, Bentley RG, McVey MJ, Chandra S, Irving EA, Andrew A Parsons, Barone FC.
    Exp Neurol; 2008 Jul 09; 212(1):53-62. PubMed ID: 18462720
    [Abstract] [Full Text] [Related]

  • 14. NXY-059, a free radical--trapping agent, substantially lessens the functional disability resulting from cerebral ischemia in a primate species.
    Marshall JW, Duffin KJ, Green AR, Ridley RM.
    Stroke; 2001 Jan 09; 32(1):190-8. PubMed ID: 11136936
    [Abstract] [Full Text] [Related]

  • 15. Effective plasma concentration of a novel Na+/Ca2+ channel blocker NS-7 for its cerebroprotective actions in rats with a transient middle cerebral artery occlusion.
    Aoki Y, Tamura M, Itoh Y, Seto T, Nonaka K, Mukai H, Ukai Y.
    J Pharmacol Exp Ther; 2001 Feb 09; 296(2):306-11. PubMed ID: 11160611
    [Abstract] [Full Text] [Related]

  • 16. A selective endothelin ET(A) receptor antagonist, SB 234551, improves cerebral perfusion following permanent focal cerebral ischemia in rats.
    Zhang Y, Belayev L, Zhao W, Irving EA, Busto R, Ginsberg MD.
    Brain Res; 2005 May 31; 1045(1-2):150-6. PubMed ID: 15910773
    [Abstract] [Full Text] [Related]

  • 17. The significance of brain temperature in focal cerebral ischemia: histopathological consequences of middle cerebral artery occlusion in the rat.
    Morikawa E, Ginsberg MD, Dietrich WD, Duncan RC, Kraydieh S, Globus MY, Busto R.
    J Cereb Blood Flow Metab; 1992 May 31; 12(3):380-9. PubMed ID: 1569134
    [Abstract] [Full Text] [Related]

  • 18. Oxyresveratrol (trans-2,3',4,5'-tetrahydroxystilbene) is neuroprotective and inhibits the apoptotic cell death in transient cerebral ischemia.
    Andrabi SA, Spina MG, Lorenz P, Ebmeyer U, Wolf G, Horn TF.
    Brain Res; 2004 Aug 13; 1017(1-2):98-107. PubMed ID: 15261105
    [Abstract] [Full Text] [Related]

  • 19. Intracarotid injection of granulocyte-macrophage colony-stimulating factor induces neuroprotection in a rat transient middle cerebral artery occlusion model.
    Nakagawa T, Suga S, Kawase T, Toda M.
    Brain Res; 2006 May 17; 1089(1):179-85. PubMed ID: 16678804
    [Abstract] [Full Text] [Related]

  • 20. Neuroprotective effects of a postischemic treatment with a bradykinin B2 receptor antagonist in a rat model of temporary focal cerebral ischemia.
    Lumenta DB, Plesnila N, Kläsner B, Baethmann A, Pruneau D, Schmid-Elsaesser R, Zausinger S.
    Brain Res; 2006 Jan 19; 1069(1):227-34. PubMed ID: 16378603
    [Abstract] [Full Text] [Related]

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