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Journal Abstract Search

536 related items for PubMed ID: 11788061

  • 1. High-density miniaturized thermal shift assays as a general strategy for drug discovery.
    Pantoliano MW, Petrella EC, Kwasnoski JD, Lobanov VS, Myslik J, Graf E, Carver T, Asel E, Springer BA, Lane P, Salemme FR.
    J Biomol Screen; 2001 Dec; 6(6):429-40. PubMed ID: 11788061
    [Abstract] [Full Text] [Related]

  • 2. Evaluation of fluorescence-based thermal shift assays for hit identification in drug discovery.
    Lo MC, Aulabaugh A, Jin G, Cowling R, Bard J, Malamas M, Ellestad G.
    Anal Biochem; 2004 Sep 01; 332(1):153-9. PubMed ID: 15301960
    [Abstract] [Full Text] [Related]

  • 3. Single-molecule detection technologies in miniaturized high throughput screening: binding assays for g protein-coupled receptors using fluorescence intensity distribution analysis and fluorescence anisotropy.
    Rüdiger M, Haupts U, Moore KJ, Pope AJ.
    J Biomol Screen; 2001 Feb 01; 6(1):29-37. PubMed ID: 11679163
    [Abstract] [Full Text] [Related]

  • 4. Novel trends in high-throughput screening.
    Mayr LM, Bojanic D.
    Curr Opin Pharmacol; 2009 Oct 01; 9(5):580-8. PubMed ID: 19775937
    [Abstract] [Full Text] [Related]

  • 5. Screening for ligands using a generic and high-throughput light-scattering-based assay.
    Senisterra GA, Markin E, Yamazaki K, Hui R, Vedadi M, Awrey DE.
    J Biomol Screen; 2006 Dec 01; 11(8):940-8. PubMed ID: 17092916
    [Abstract] [Full Text] [Related]

  • 6. Quantitative determination of protein stability and ligand binding using a green fluorescent protein reporter system.
    Moreau MJ, Morin I, Schaeffer PM.
    Mol Biosyst; 2010 Jul 01; 6(7):1285-92. PubMed ID: 20454718
    [Abstract] [Full Text] [Related]

  • 7. Miniaturization of intracellular calcium functional assays to 1536-well plate format using a fluorometric imaging plate reader.
    Hodder P, Mull R, Cassaday J, Berry K, Strulovici B.
    J Biomol Screen; 2004 Aug 01; 9(5):417-26. PubMed ID: 15296641
    [Abstract] [Full Text] [Related]

  • 8. Ligand screening using fluorescence thermal shift analysis (FTS).
    Luan CH, Light SH, Dunne SF, Anderson WF.
    Methods Mol Biol; 2014 Aug 01; 1140():263-89. PubMed ID: 24590724
    [Abstract] [Full Text] [Related]

  • 9. Validation of an optical microplate label-free platform in the screening of chemical libraries for direct binding to a nuclear receptor.
    Vela L, Lowe PN, Gerstenmaier J, Laing LG, Stimmel JB, Orband-Miller LA, Martin JJ.
    Assay Drug Dev Technol; 2011 Oct 01; 9(5):532-48. PubMed ID: 21438675
    [Abstract] [Full Text] [Related]

  • 10. Cell-based protein stabilization assays for the detection of interactions between small-molecule inhibitors and BRD4.
    Schulze J, Moosmayer D, Weiske J, Fernández-Montalván A, Herbst C, Jung M, Haendler B, Bader B.
    J Biomol Screen; 2015 Feb 01; 20(2):180-9. PubMed ID: 25266565
    [Abstract] [Full Text] [Related]

  • 11. Screening Chemoreceptor-Ligand Interactions by High-Throughput Thermal-Shift Assays.
    Ehrhardt MKG, Warring SL, Gerth ML.
    Methods Mol Biol; 2018 Feb 01; 1729():281-290. PubMed ID: 29429098
    [Abstract] [Full Text] [Related]

  • 12. Ligand-receptor interaction platforms and their applications for drug discovery.
    Fang Y.
    Expert Opin Drug Discov; 2012 Oct 01; 7(10):969-88. PubMed ID: 22860803
    [Abstract] [Full Text] [Related]

  • 13. An Alternative Thiol-Reactive Dye to Analyze Ligand Interactions with the Chemokine Receptor CXCR2 Using a New Thermal Shift Assay Format.
    Bergsdorf C, Fiez-Vandal C, Sykes DA, Bernet P, Aussenac S, Charlton SJ, Schopfer U, Ottl J, Duckely M.
    J Biomol Screen; 2016 Mar 01; 21(3):243-51. PubMed ID: 26644402
    [Abstract] [Full Text] [Related]

  • 14. Monitoring drug target engagement in cells and tissues using the cellular thermal shift assay.
    Martinez Molina D, Jafari R, Ignatushchenko M, Seki T, Larsson EA, Dan C, Sreekumar L, Cao Y, Nordlund P.
    Science; 2013 Jul 05; 341(6141):84-7. PubMed ID: 23828940
    [Abstract] [Full Text] [Related]

  • 15. Fluorescence polarization is a useful technology for reagent reduction in assay miniaturization.
    Kowski TJ, Wu JJ.
    Comb Chem High Throughput Screen; 2000 Oct 05; 3(5):437-44. PubMed ID: 11032959
    [Abstract] [Full Text] [Related]

  • 16. Receptor-ligand interactions studied with homogeneous fluorescence-based assays suitable for miniaturized screening.
    Scheel AA, Funsch B, Busch M, Gradl G, Pschorr J, Lohse MJ.
    J Biomol Screen; 2001 Feb 05; 6(1):11-8. PubMed ID: 11679161
    [Abstract] [Full Text] [Related]

  • 17. Thermodynamic analysis of ligand-induced changes in protein thermal unfolding applied to high-throughput determination of ligand affinities with extrinsic fluorescent dyes.
    Layton CJ, Hellinga HW.
    Biochemistry; 2010 Dec 28; 49(51):10831-41. PubMed ID: 21050007
    [Abstract] [Full Text] [Related]

  • 18. Miniaturization of fluorescence polarization receptor-binding assays using CyDye-labeled ligands.
    Harris A, Cox S, Burns D, Norey C.
    J Biomol Screen; 2003 Aug 28; 8(4):410-20. PubMed ID: 14567793
    [Abstract] [Full Text] [Related]

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  • 20. Miniaturization of whole live cell-based GPCR assays using microdispensing and detection systems.
    Kornienko O, Lacson R, Kunapuli P, Schneeweis J, Hoffman I, Smith T, Alberts M, Inglese J, Strulovici B.
    J Biomol Screen; 2004 Apr 28; 9(3):186-95. PubMed ID: 15140380
    [Abstract] [Full Text] [Related]

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